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IMMUNE 3D

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ROCKVILLE, Maryland, US

About IMMUNE 3D

3D cultures are built to provide multi-layer, tissue like structures that mimic the architecture of cells in vivo. 3D cultures are conducive to capturing the extracellular matrix (ECM) that is critical to studying the biology of disease. 3D cultures provide a suitable micro-environment for optimal cell growth, differentiation and function, and the ability to create...

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3D cultures are built to provide multi-layer, tissue like structures that mimic the architecture of cells in vivo. 3D cultures are conducive to capturing the extracellular matrix (ECM) that is critical to studying the biology of disease. 3D cultures provide a suitable micro-environment for optimal cell growth, differentiation and function, and the ability to create tissue-like constructs in vitro.

 

The immune system plays a role in many major diseases by protecting us against infectious agents and malignant cells or by causing disease in the case of autoimmunity.

 

The cross talk between immune cells and the ECM provide a foundation to understanding factors that play a role in cell migration, motility and immune escape.

 

IMMUNE 3D aims to merge our in-depth know-how on 3D cultures and immunology to develop novel 3D platforms that capture the disease environment for cost-effective discovery, screening and acceleration of therapies and biomarkers.

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Our Services (79)


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Neoantigen Identification

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Tissue Cross Reactivity Studies

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T-cell Engineering

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T Cell Activation and Proliferation Assays

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Specialized Cell-Based Assays

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TCR Screening and Validation

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CAR-T Cell Therapy Development

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Receptor Binding Assays

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Receptor Assays

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Metabolite Profiling

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Macrophage Activation Assay

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Ligand Binding Assays

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Lead Identification and Validation

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In vitro Toxicity Testing

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In vitro Reporter Gene Assays

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In vitro Pharmacology Studies

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In vitro Oncology Models

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In vitro Immunotoxicity Testing

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In vitro Immunogenicity Assays

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In vitro Drug Efficacy Testing

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Immunotherapy Screening

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Immunophenotyping

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Immuno-oncology Assays

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Immunoassays

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Immune Function Testing

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Immune Checkpoint Assays

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Human Immune Cell Assays

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Immune Cell Assays

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Hit Validation

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Hit to Lead and Lead Optimization

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Hit Identification

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Histone Deacetylase (HDAC) Assays

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Functional Human Tissue Assays

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Functional & Cell Type Specific Assays

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Flow Cytometry

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Ex Vivo Models and Assays

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Epigenetic Studies

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Drug Target Validation

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Drug Target Identification

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Drug Discovery

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Cytokine Analysis

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Custom Cell-Based Assay Development

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Biomolecular Interaction Analysis

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Biomarker Discovery

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Biomarkers

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Cytotoxic T Cell Assays

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Cytotoxicity Assays

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CTL Assay

Cytotoxic T Lymphocyte Assays, CTL and Patient-Matched Tumor Assays, Patient-Specific CTL Assays
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Compound Profiling in Immune Cell Panels

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Compound Profiling in Cancer Cell Panels

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Compound Profiling

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Chemotaxis Assays

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PD-1 Assays

Programmed Cell Death Protein-1 Checkpoint Assays
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Checkpoint Kinase-1 (ChK-1) Assays

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Cellular Metabolism Assays

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Cell-Based Screening Methods

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Cell-Based Compound Screening

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Cell-Based Assays

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Cell Viability & Proliferation Assays

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Cell Signaling Analyses

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Cell Proliferation Assays

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Cell Line Generation

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Cell Death Assays

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Cell Co-Cultivation

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Cell Adhesion Assays

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Assay Development

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In vitro ADME/DMPK Studies

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ADCC and CDC Assays

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3D Cell Culture Model Analytics

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3-D Human Tumor Platform for Drug Discovery

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Tumor Heterogeneity Analysis

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Tumor Profiling

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Analysis of Tumor Infiltrating Lymphocytes (IL/TIL)

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Cell Invasion & Migration Assays

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Cell Migration Assays

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3D Tumor Models

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3D Cell-Based Assays

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3D Cell Culture Models

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3D Modeling

Three Dimensional Modeling
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IMMUNE 3D ® is a unique and proprietary platform that is designed to capture the core cell types to effectively capture the extracellular matrix. The platform was initially designed to naturally observe the migration patterns of immune cells and to interrogate the stromal environments that cells need to permeate... Show more »

IMMUNE 3D ® is a unique and proprietary platform that is designed to capture the core cell types to effectively capture the extracellular matrix. The platform was initially designed to naturally observe the migration patterns of immune cells and to interrogate the stromal environments that cells need to permeate to reach their destinations. Over the last few years, we have applied our understanding of the role that immune cells play in various diseases into developing 3D models that capture the disease biology in an immune context.

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Kaitlin Reed

Business Development Associate

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