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Immundnz Ltd.

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Alderley Edge, GB

About Immundnz Ltd.

Immundnz is a CRO specialised in immunology, immune modelling, immune response and tissue damage analysis, in vivo and in vitro cell culture systems and complex bioanalytical chemistry for preclinical drug research and development. We are located in the Netherlands and at the prestigious Alderley Park campus in Cheshire, UK, where we have an established immunology laboratory.

Our Services (49)


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In vitro Immune Function Testing

Price on request
  • Consultants in designing the model for immune response in in vitro and in vivo
  • Laboratory experiments (in vivo and/or in vitro) to test the model
  • Human in vitro systems and mammalian in vivo systems

Why is Immune Modelling Important?

You will need an immune model if developing an immunotherapeutic that is expected... Show more »

  • Consultants in designing the model for immune response in in vitro and in vivo
  • Laboratory experiments (in vivo and/or in vitro) to test the model
  • Human in vitro systems and mammalian in vivo systems

Why is Immune Modelling Important?

You will need an immune model if developing an immunotherapeutic that is expected to function through generating an immune response (e.g. against tumours) or if the drug targets an immune condition (e.g. autoimmunity) or if the drug might generate an adverse immune response.

The adaptive immune system is a very complex system that is structured through a cascade of cells, receptors and cytokines that process, respond, initiate, memorise and deliver an immune response.

In a sterile inflammatory state, as in a drug-induced effect, the immune effectors interact with the tissue of the body to produce a cell mediated and/or antibody mediated immunity.

This is studied through appropriate immune model that is designed by immunologists with the relevant experience and insight.

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Immune Cell Assays

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Cell Death Assays

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Mammalian Cell Culture

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Cell culture systems are at the heart of our expertise and services. We grow human and mammalian cells in various culture media, both adherent and non-adherent (e.g. lymphocytes) type. We grow various established and primary human cells in our lab that represent human tissue systems such as:

Cell culture systems are at the heart of our expertise and services. We grow human and mammalian cells in various culture media, both adherent and non-adherent (e.g. lymphocytes) type. We grow various established and primary human cells in our lab that represent human tissue systems such as:

  • Aortic smooth muscle cells (SMCs)
  • Lung epithelial cells (A549)
  • Embryonic renal cells (HEK293)
  • Hepatic cells (HepG2)
  • Cervical cancer cells (HeLa)
  • Placental cells (BeWo)
  • Retinal epithelial cells (ARPE19)
  • Neuronal cells (SY5Y)
  • Prostate cancer cells (PC3)
  • Lymphocytic cells (THP1, TALL1, BALL1)
  • Monocyte derived dendritic cells
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Immunology Animal Models

Price on request
  • Consultants in designing the model for immune response in in vitro and in vivo
  • Laboratory experiments (in vivo and/or in vitro) to test the model
  • Human in vitro systems and mammalian in vivo systems

Why is Immune Modelling Important?

You will need an immune model if developing an immunotherapeutic that is expected... Show more »

  • Consultants in designing the model for immune response in in vitro and in vivo
  • Laboratory experiments (in vivo and/or in vitro) to test the model
  • Human in vitro systems and mammalian in vivo systems

Why is Immune Modelling Important?

You will need an immune model if developing an immunotherapeutic that is expected to function through generating an immune response (e.g. against tumours) or if the drug targets an immune condition (e.g. autoimmunity) or if the drug might generate an adverse immune response.

The adaptive immune system is a very complex system that is structured through a cascade of cells, receptors and cytokines that process, respond, initiate, memorise and deliver an immune response.

In a sterile inflammatory state, as in a drug-induced effect, the immune effectors interact with the tissue of the body to produce a cell mediated and/or antibody mediated immunity.

This is studied through appropriate immune model that is designed by immunologists with the relevant experience and insight.

Show less

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Necrosis Assays

Price on request

Tissue Damage Assessment

The endogenous molecules or proteins that are released by cells through drug-induced necrosis or compromised membrane are activators of an immune response. By characterising these molecules in cells and cell fluids in combination with pathway analysis, we are able to assess drug-induced tissue... Show more »

Tissue Damage Assessment

The endogenous molecules or proteins that are released by cells through drug-induced necrosis or compromised membrane are activators of an immune response. By characterising these molecules in cells and cell fluids in combination with pathway analysis, we are able to assess drug-induced tissue damage. This is a very important step in drug risk assessment at preclinical stage.

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Immunoassays

Price on request

Immunoassays Services

Immunoassays Services

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Bioanalytical Assays

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Bioanalytical Assays Services

Bioanalytical Assays Services

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Bioanalysis

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Bioanalysis Services

Bioanalysis Services

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Pharmacology & Toxicology

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Pharmacology & Toxicology Services

Pharmacology & Toxicology Services

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Bioanalytical Assay Validation

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Bioanalytical Assay Development and Optimization

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Liposome Immunoassay

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Large Molecule Bioanalysis

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Small Molecule Bioanalysis

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Cell Permeability Assay

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Apoptosis Assays

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Cell Culture Consulting

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Surface Plasmon Resonance (SPR)

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Size Exclusion Chromatography (SEC)

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HPLC assay for SEC, titer

HPLC assay for SEC, titer

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Stem Cell Assays

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Cell Disruption

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Therapeutic Drug Monitoring

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Experimental Services

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Cell Invasion & Migration Assays

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Primary Cell Culture

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Subcellular Fractionation

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Imaging & Spectroscopy

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Cytokine Storm Testing

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Cytokine Analysis

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In vitro Immunogenicity Assays

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Immunostaining

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Immunostaining Services

Immunostaining Services

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Protein Expression Visualization

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Protein Expression Visualization Services

Protein Expression Visualization Services

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Protein Services

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Protein Services

Protein Services

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Biochemistry & Molecular Biology

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Biochemistry & Molecular Biology Services

Biochemistry & Molecular Biology Services

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Immunohistochemistry (IHC)

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Cell Lines

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Project Management

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Omics

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Chromatography

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Chromatography Services

Chromatography Services

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Separation/Purification Services

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Purification Services

Purification Services

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Analytical Chemistry Services

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Analytical Chemistry Services

Analytical Chemistry Services

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Chemistry and Materials

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Chemistry and Materials Services

Chemistry and Materials Services

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Functional & Cell Type Specific Assays

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Functional & Cell Type Specific Assays Services

Functional & Cell Type Specific Assays Services

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Cell-Based Assays

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Cell-Based Assays Services

Cell-Based Assays Services

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Cell and Tissue Culture

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Cell and Tissue Culture Services

Cell and Tissue Culture Services

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Cells and Tissues

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Cells and Tissues Services

Cells and Tissues Services

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Biology

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Biology Services

Biology Services

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Custom Cell-Based Assay Development

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