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In vitro Immune Function Testing
- Consultants in designing the model for immune response in in vitro and in vivo
- Laboratory experiments (in vivo and/or in vitro) to test the model
- Human in vitro systems and mammalian in vivo systems
Why is Immune Modelling Important?
You will need an immune model if developing an immunotherapeutic that is expected... Show more »
- Consultants in designing the model for immune response in in vitro and in vivo
- Laboratory experiments (in vivo and/or in vitro) to test the model
- Human in vitro systems and mammalian in vivo systems
Why is Immune Modelling Important?
You will need an immune model if developing an immunotherapeutic that is expected to function through generating an immune response (e.g. against tumours) or if the drug targets an immune condition (e.g. autoimmunity) or if the drug might generate an adverse immune response.
The adaptive immune system is a very complex system that is structured through a cascade of cells, receptors and cytokines that process, respond, initiate, memorise and deliver an immune response.
In a sterile inflammatory state, as in a drug-induced effect, the immune effectors interact with the tissue of the body to produce a cell mediated and/or antibody mediated immunity.
This is studied through appropriate immune model that is designed by immunologists with the relevant experience and insight.
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Cell culture systems are at the heart of our expertise and services. We grow human and mammalian cells in various culture media, both adherent and non-adherent (e.g. lymphocytes) type. We grow various established and primary human cells in our lab that represent human tissue systems such as:
Cell culture systems are at the heart of our expertise and services. We grow human and mammalian cells in various culture media, both adherent and non-adherent (e.g. lymphocytes) type. We grow various established and primary human cells in our lab that represent human tissue systems such as:
- Aortic smooth muscle cells (SMCs)
- Lung epithelial cells (A549)
- Embryonic renal cells (HEK293)
- Hepatic cells (HepG2)
- Cervical cancer cells (HeLa)
- Placental cells (BeWo)
- Retinal epithelial cells (ARPE19)
- Neuronal cells (SY5Y)
- Prostate cancer cells (PC3)
- Lymphocytic cells (THP1, TALL1, BALL1)
- Monocyte derived dendritic cells
- Consultants in designing the model for immune response in in vitro and in vivo
- Laboratory experiments (in vivo and/or in vitro) to test the model
- Human in vitro systems and mammalian in vivo systems
Why is Immune Modelling Important?
You will need an immune model if developing an immunotherapeutic that is expected... Show more »
- Consultants in designing the model for immune response in in vitro and in vivo
- Laboratory experiments (in vivo and/or in vitro) to test the model
- Human in vitro systems and mammalian in vivo systems
Why is Immune Modelling Important?
You will need an immune model if developing an immunotherapeutic that is expected to function through generating an immune response (e.g. against tumours) or if the drug targets an immune condition (e.g. autoimmunity) or if the drug might generate an adverse immune response.
The adaptive immune system is a very complex system that is structured through a cascade of cells, receptors and cytokines that process, respond, initiate, memorise and deliver an immune response.
In a sterile inflammatory state, as in a drug-induced effect, the immune effectors interact with the tissue of the body to produce a cell mediated and/or antibody mediated immunity.
This is studied through appropriate immune model that is designed by immunologists with the relevant experience and insight.
Tissue Damage Assessment
The endogenous molecules or proteins that are released by cells through drug-induced necrosis or compromised membrane are activators of an immune response. By characterising these molecules in cells and cell fluids in combination with pathway analysis, we are able to assess drug-induced tissue... Show more »
Tissue Damage Assessment
The endogenous molecules or proteins that are released by cells through drug-induced necrosis or compromised membrane are activators of an immune response. By characterising these molecules in cells and cell fluids in combination with pathway analysis, we are able to assess drug-induced tissue damage. This is a very important step in drug risk assessment at preclinical stage.
Bioanalytical Assays Services
Pharmacology & Toxicology
Pharmacology & Toxicology Services
Bioanalytical Assay Validation
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Bioanalytical Assay Development and Optimization
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Large Molecule Bioanalysis
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Small Molecule Bioanalysis
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Surface Plasmon Resonance (SPR)
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Size Exclusion Chromatography (SEC)
HPLC assay for SEC, titer
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Therapeutic Drug Monitoring
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Cell Invasion & Migration Assays
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In vitro Immunogenicity Assays
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Protein Expression Visualization
Protein Expression Visualization Services
Biochemistry & Molecular Biology
Biochemistry & Molecular Biology Services
Immunohistochemistry (IHC)
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Project and Process Management
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Analytical Chemistry Services
Analytical Chemistry Services
Chemistry and Materials Services
Functional & Cell Type Specific Assays
Functional & Cell Type Specific Assays Services
Functional & Cell Type Specific Assays Services
Cell-Based Assays Services
Cell and Tissue Culture Services
Cells and Tissues Services
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