Immundnz Ltd.
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Alderley Edge, GB
Immundnz is a CRO specialised in immunology, immune modelling, immune response and tissue damage analysis, in vivo and in vitro cell culture systems and complex bioanalytical chemistry for preclinical drug research and development. We are located in the Netherlands and at the prestigious Alderley Park campus in Cheshire, UK, where we have an established immunology laboratory.
Why is Immune Modelling Important?
You will need an immune model if developing an immunotherapeutic that is expected... Show more »
Why is Immune Modelling Important?
You will need an immune model if developing an immunotherapeutic that is expected to function through generating an immune response (e.g. against tumours) or if the drug targets an immune condition (e.g. autoimmunity) or if the drug might generate an adverse immune response.
The adaptive immune system is a very complex system that is structured through a cascade of cells, receptors and cytokines that process, respond, initiate, memorise and deliver an immune response.
In a sterile inflammatory state, as in a drug-induced effect, the immune effectors interact with the tissue of the body to produce a cell mediated and/or antibody mediated immunity.
This is studied through appropriate immune model that is designed by immunologists with the relevant experience and insight.
Cell culture systems are at the heart of our expertise and services. We grow human and mammalian cells in various culture media, both adherent and non-adherent (e.g. lymphocytes) type. We grow various established and primary human cells in our lab that represent human tissue systems such as:
Cell culture systems are at the heart of our expertise and services. We grow human and mammalian cells in various culture media, both adherent and non-adherent (e.g. lymphocytes) type. We grow various established and primary human cells in our lab that represent human tissue systems such as:
Why is Immune Modelling Important?
You will need an immune model if developing an immunotherapeutic that is expected... Show more »
Why is Immune Modelling Important?
You will need an immune model if developing an immunotherapeutic that is expected to function through generating an immune response (e.g. against tumours) or if the drug targets an immune condition (e.g. autoimmunity) or if the drug might generate an adverse immune response.
The adaptive immune system is a very complex system that is structured through a cascade of cells, receptors and cytokines that process, respond, initiate, memorise and deliver an immune response.
In a sterile inflammatory state, as in a drug-induced effect, the immune effectors interact with the tissue of the body to produce a cell mediated and/or antibody mediated immunity.
This is studied through appropriate immune model that is designed by immunologists with the relevant experience and insight.
Tissue Damage Assessment
The endogenous molecules or proteins that are released by cells through drug-induced necrosis or compromised membrane are activators of an immune response. By characterising these molecules in cells and cell fluids in combination with pathway analysis, we are able to assess drug-induced tissue... Show more »
Tissue Damage Assessment
The endogenous molecules or proteins that are released by cells through drug-induced necrosis or compromised membrane are activators of an immune response. By characterising these molecules in cells and cell fluids in combination with pathway analysis, we are able to assess drug-induced tissue damage. This is a very important step in drug risk assessment at preclinical stage.
Immunoassays Services
Immunoassays Services
Bioanalytical Assays Services
Bioanalytical Assays Services
Bioanalysis Services
Bioanalysis Services
Pharmacology & Toxicology Services
Pharmacology & Toxicology Services
HPLC assay for SEC, titer
HPLC assay for SEC, titer
Immunostaining Services
Immunostaining Services
Protein Expression Visualization Services
Protein Expression Visualization Services
Protein Services
Protein Services
Biochemistry & Molecular Biology Services
Biochemistry & Molecular Biology Services
Chromatography Services
Chromatography Services
Purification Services
Purification Services
Analytical Chemistry Services
Analytical Chemistry Services
Chemistry and Materials Services
Chemistry and Materials Services
Functional & Cell Type Specific Assays Services
Functional & Cell Type Specific Assays Services
Cell-Based Assays Services
Cell-Based Assays Services
Cell and Tissue Culture Services
Cell and Tissue Culture Services
Cells and Tissues Services
Cells and Tissues Services
Biology Services
Biology Services
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