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Immundnz Ltd.

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Alderley Edge, GB

About Immundnz Ltd.

Immundnz is a CRO specialised in immunology, immune modelling, immune response and tissue damage analysis, in vitro cell culture systems and complex bioanalytical chemistry for preclinical drug research and development. We are located in the Netherlands and in the UK, where we have an established immunology laboratory.

Our Services (50)


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Cell Co-Cultivation

Price on request

Cell co-culutures for in vitro immunology research

Cell co-culutures for in vitro immunology research

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Dendritic Cell Generation

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Dendritic cell generation and maturation assays

Dendritic cell generation and maturation assays

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T Cell Activation and Proliferation Assays

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T-cell activation and proliferation assays for in vitro immunology research

T-cell activation and proliferation assays for in vitro immunology research

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T-Helper Cell Polarization Assays

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T-Helper Cell Polarization Assays for in vitro immunology research

T-Helper Cell Polarization Assays for in vitro immunology research

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Mixed Lymphocyte Reactions

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Mixed Lymphocyte eaction assays for immunology research

Mixed Lymphocyte eaction assays for immunology research

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In vitro Immune Function Testing

Price on request

-Laboratory experiments (in vivo and/or in vitro) to test the model 

-Human in vitro systems and mammalian in vivo systems

-Laboratory experiments (in vivo and/or in vitro) to test the model 

-Human in vitro systems and mammalian in vivo systems

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Immune Cell Assays

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Cell Death Assays

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Mammalian Cell Culture

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Cell culture systems are at the heart of our expertise and services. We grow human and mammalian cells in various culture media, both adherent and non-adherent (e.g. lymphocytes) type. We grow various established and primary human cells in our lab that represent human tissue systems such as:

Cell culture systems are at the heart of our expertise and services. We grow human and mammalian cells in various culture media, both adherent and non-adherent (e.g. lymphocytes) type. We grow various established and primary human cells in our lab that represent human tissue systems such as:

  • Aortic smooth muscle cells (SMCs)
  • Lung epithelial cells (A549)
  • Embryonic renal cells (HEK293)
  • Hepatic cells (HepG2)
  • Cervical cancer cells (HeLa)
  • Placental cells (BeWo)
  • Retinal epithelial cells (ARPE19)
  • Neuronal cells (SY5Y)
  • Prostate cancer cells (PC3)
  • Lymphocytic cells (THP1, TALL1, BALL1)
  • Monocyte derived dendritic cells
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Necrosis Assays

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Tissue Damage Assessment

The endogenous molecules or proteins that are released by cells through drug-induced necrosis or compromised membrane are activators of an immune response. By characterising these molecules in cells and cell fluids in combination with pathway analysis, we are able to assess drug-induced tissue... Show more »

Tissue Damage Assessment

The endogenous molecules or proteins that are released by cells through drug-induced necrosis or compromised membrane are activators of an immune response. By characterising these molecules in cells and cell fluids in combination with pathway analysis, we are able to assess drug-induced tissue damage. This is a very important step in drug risk assessment at preclinical stage.

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Immunoassays

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Immunoassays Services

Immunoassays Services

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Bioanalytical Assays

Price on request

•Antibody characterisation
•Intact mAb molecular mass analysis
•Sequencing
•Fab, Fc, HC, LC
•Epitope mapping
•Post-translational modifications
•Aggregate analysis
•Impurity profiling


•BioanalysisShow more »

•Antibody characterisation
•Intact mAb molecular mass analysis
•Sequencing
•Fab, Fc, HC, LC
•Epitope mapping
•Post-translational modifications
•Aggregate analysis
•Impurity profiling


•Bioanalysis
•Quantification of biopharmaceuticals in biological matrices

•Proteomics
•Analysis of proteins involved in immune response
•Top-down (intact proteins)
•Bottom-up (digested proteins)
•Targeted (knowledge based)
•Untargeted (discovery)
•Multivariate data analysis

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Bioanalytical Assay Development and Optimization

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Liposome Immunoassay

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Large Molecule Bioanalysis

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Cell Permeability Assay

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Apoptosis Assays

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Surface Plasmon Resonance (SPR)

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Size Exclusion Chromatography (SEC)

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HPLC assay for SEC, titer

HPLC assay for SEC, titer

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Stem Cell Assays

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Cell Disruption

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Cell Invasion & Migration Assays

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Primary Cell Culture

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Subcellular Fractionation

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Imaging & Spectroscopy

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Cytokine Storm Testing

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Cytokine Analysis

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In vitro Immunogenicity Assays

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Immunostaining

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Immunostaining Services

Immunostaining Services

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Protein Expression Visualization

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Protein Expression Visualization Services

Protein Expression Visualization Services

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Immunohistochemistry (IHC)

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Cell Lines

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Project Management

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Omics

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Chromatography

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Chromatography Services

Chromatography Services

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Separation/Purification Services

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Purification Services

Purification Services

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Functional & Cell Type Specific Assays

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Functional & Cell Type Specific Assays Services

Functional & Cell Type Specific Assays Services

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Cell-Based Assays

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Cell-Based Assays Services

Cell-Based Assays Services

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Cell and Tissue Culture

Price on request

Cell and Tissue Culture Services

Cell and Tissue Culture Services

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Cells and Tissues

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Cells and Tissues Services

Cells and Tissues Services

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Biology

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Biology Services

Biology Services

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Custom Cell-Based Assay Development

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Signaling Pathway Analysis

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Cell-Based Compound Screening

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Bioinformatics

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Protein-Protein Interaction Analysis

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Immunoprecipitation

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Western Blot

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Immunocytochemistry

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Cell Line Authentication

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Robert-Jan Lamers

Co-founder and director

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