Imavita
About Imavita
Imavita is an innovating technology company proposing preclinical services in the exploration of preclinical models of human pathologies by the use of innovating imaging techniques.
The vision of our company is to propose to pharmaceutical industries, biotechnology companies and other private & public... Show more »
Imavita is an innovating technology company proposing preclinical services in the exploration of preclinical models of human pathologies by the use of innovating imaging techniques.
The vision of our company is to propose to pharmaceutical industries, biotechnology companies and other private & public laboratories, innovating solutions in efficacy / toxicity evaluation of active ingredients in laboratory species by the use of non invasive imaging techniques and appropriate imaging analysis for quantitative evaluation of specific imaging biomarkers.
Imavita is actually developing the following tools:
- Pre-clinical testing in laboratory species (induction of pathologies / treatment & sampling phases)
- Imaging techniques like SPECT/CT, CT with Single/Dual Energy CT approach, MRI, ultrasonography, etc…
- Images exploitation and analysis for quantitative imaging
Imavita is planning to focus its activities in the following domains:
- Cardiovascular diseases
- Osteo-articular pathologies
- Dermatology
- Oncology
- Neurology
- Drug disposition / PK
- Medical Devices
Imavita is member of AFSSI (“Association Française des Sociétés de Services et d’Innovation pour les Sciences de la Vie” / French association of innovating services companies in life sciences)
Imavita is ISO9001 certified.
Our Services (7)
In vivo Drug Efficacy Testing
Imavita proposes preclinical models which can be used alone or associated with imaging modalities to permit the evaluation of efficacy of new compounds / new therapeutics treatments in development phase.
Species / strains
- Rodents (rat / mouse / hamster / Guinea pig)
- Non rodents (rabbits / pig / sheep / goat)
- Fish... Show more »
Imavita proposes preclinical models which can be used alone or associated with imaging modalities to permit the evaluation of efficacy of new compounds / new therapeutics treatments in development phase.
Species / strains
- Rodents (rat / mouse / hamster / Guinea pig)
- Non rodents (rabbits / pig / sheep / goat)
- Fish (zebra fish)
- Healthy / normal models
Type of studies
- Pharmacokinetics / early PK
- Pharmacodynamics / PK/PD relationships
- Biodistribution / Elimination evaluation
Example of projects
- PK / early PK / PK/PD with serial or terminal sampling animals (in-life phase)
- PK on catheterized animals (jugular / femoral / combined) for PK and/or PK/PD studies (in-life phase)
- Bile / lymph / cerebrospinal fluid catheterized rats for pharmacokinetics evaluation / transport evaluation of molecules / PK/PD relationships (in-life phase)
- Telemetry studies (core temperature / ECG / EMG /EEG) combined or not with catheterized animals for PK/PD evaluation or safety pharmacology
- Pathological models / induced pathologies
Type of studies
- Evaluation of pharmacokinetics on pathological animals / impact of pathology on PK parameters
- Efficacy studies with different approaches:
- Classical approach / parallel groups
- Longitudinal study (repeated measure experiment) by applying imaging modalities
Example of projects
- Efficacy studies in myocardial infarction induced rat
- Efficacy of new molecules on bone healing in normal & osteoporosis rat model
- Efficacy of new molecules on skin healing (wound / burn in mice or rat)
Resources
- Access to conventional facilities / SPF / SOPF for rodents
- Access to conventional facilities for large species
PBPK Modeling
In silico absorption, distribution, metabolism, and excretion
Imavita proposes preclinical models which can be used alone or associated with imaging modalities to permit the evaluation of efficacy of new compounds / new therapeutics treatments in development phase.
Species / strains
- Rodents (rat / mouse / hamster / Guinea pig)
- Non rodents (rabbits / pig / sheep / goat)
- Fish... Show more »
Imavita proposes preclinical models which can be used alone or associated with imaging modalities to permit the evaluation of efficacy of new compounds / new therapeutics treatments in development phase.
Species / strains
- Rodents (rat / mouse / hamster / Guinea pig)
- Non rodents (rabbits / pig / sheep / goat)
- Fish (zebra fish)
- Healthy / normal models
Type of studies
- Pharmacokinetics / early PK
- Pharmacodynamics / PK/PD relationships
- Biodistribution / Elimination evaluation
Example of projects
- PK / early PK / PK/PD with serial or terminal sampling animals (in-life phase)
- PK on catheterized animals (jugular / femoral / combined) for PK and/or PK/PD studies (in-life phase)
- Bile / lymph / cerebrospinal fluid catheterized rats for pharmacokinetics evaluation / transport evaluation of molecules / PK/PD relationships (in-life phase)
- Telemetry studies (core temperature / ECG / EMG /EEG) combined or not with catheterized animals for PK/PD evaluation or safety pharmacology
- Pathological models / induced pathologies
Type of studies
- Evaluation of pharmacokinetics on pathological animals / impact of pathology on PK parameters
- Efficacy studies with different approaches:
- Classical approach / parallel groups
- Longitudinal study (repeated measure experiment) by applying imaging modalities
Example of projects
- Efficacy studies in myocardial infarction induced rat
- Efficacy of new molecules on bone healing in normal & osteoporosis rat model
- Efficacy of new molecules on skin healing (wound / burn in mice or rat)
Resources
- Access to conventional facilities / SPF / SOPF for rodents
- Access to conventional facilities for large species
ADME/DMPK Studies
Drug Metabolism and Pharmacokinetics
Pharmacology & Toxicology
Microscopy
Imaging & Spectroscopy
Safety Pharmacology
Not finding what you're looking for?
Get info on this provider's capabilities without requesting a quote.Eric Lacoste
CEO/CSO
Imavita has not received any reviews.
Imavita has not received any endorsements.