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IBT Bioservices

Gaithersburg, Maryland, US

IBT Bioservices is a research organization offering R&D services to identify and develop vaccines and therapeutics for infectious diseases. As a division of Integrated BioTherapeutics, Inc., IBT is a small business as defined by the SBA and meets the US Government’s requirements for small business subcontracting. IBT’s principals Dr. M. Javad Aman and Dr. Kelly Warfield have a long track record of accomplishments in the filovirus field including highly productive tenures at USAMRIID. Our business is focused on a collaborative “scientist-to-scientist” model where creativity, client interaction, and expertise are emphasized. This focus allows us to keep our costs down with non-GLP preclinical studies that play an integral role in making go, no-go decisions in drug development. We offer the core functions of early R&D including initial screens in vitro and in vivo, animal model development, assay development,... Show more »

IBT Bioservices is a research organization offering R&D services to identify and develop vaccines and therapeutics for infectious diseases. As a division of Integrated BioTherapeutics, Inc., IBT is a small business as defined by the SBA and meets the US Government’s requirements for small business subcontracting. IBT’s principals Dr. M. Javad Aman and Dr. Kelly Warfield have a long track record of accomplishments in the filovirus field including highly productive tenures at USAMRIID. Our business is focused on a collaborative “scientist-to-scientist” model where creativity, client interaction, and expertise are emphasized. This focus allows us to keep our costs down with non-GLP preclinical studies that play an integral role in making go, no-go decisions in drug development. We offer the core functions of early R&D including initial screens in vitro and in vivo, animal model development, assay development, immunogenicity testing, and serology testing.

Certifications: AAALAC accredited for all animal services

Instrumentation: MSD, multiplex platform, spectrophotometers, centrifuges

Custom Animal Model Development:
IBT Bioservices can develop and establish custom animal disease models for your in vivo research efforts. We can perform up to BSL-2 work in our animal facilities. Through a network of partners, we can design and manage your BSL-3 studies as well.

Standard deliverables:
Animal studies: serum / tissues are mailed back
In vitro: results compiled in electronic format - raw data in excel, powerpoint for overall presentation, and formal reports in pdf

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Flow Cytometry
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Influenza Animal Models
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Zika Antiviral Testing
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New! In Vitro testing and animal model

New! In Vitro testing and animal model

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Antiviral Testing
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Test for inhibition of cytopathic effect (cell death) or reduction of virus yield in our cell based antiviral assays. The viruses currently available for testing are Chikungunya, Venezuelan Equine Encephalitis, Dengue 1-4, Japanese Encephalitis, Yellow Fever, Junin, Influenza H1N1, Influenza H3N2, Influenza B, Rift Valley Fever,... Show more »

Test for inhibition of cytopathic effect (cell death) or reduction of virus yield in our cell based antiviral assays. The viruses currently available for testing are Chikungunya, Venezuelan Equine Encephalitis, Dengue 1-4, Japanese Encephalitis, Yellow Fever, Junin, Influenza H1N1, Influenza H3N2, Influenza B, Rift Valley Fever, La Crosse, Vaccinia, Zika Virus, and Respiratory Syncytial Virus. Tests are performed at BSL-2 where attenuated strains of high containment viruses are used at much lower cost than wild type.

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Assay Development
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IBT Bioservices has a core competency in the development of assays that support the early research and development of vaccines, biotherapeutics, and drugs. Our capabilities include assay feasibility, reagent sourcing and qualification, optimization, and sample analysis. Our team has extensive experience in both ELISA and... Show more »

IBT Bioservices has a core competency in the development of assays that support the early research and development of vaccines, biotherapeutics, and drugs. Our capabilities include assay feasibility, reagent sourcing and qualification, optimization, and sample analysis. Our team has extensive experience in both ELISA and enzymatic assays. Immunogenicity assays for vaccines and biologics are our specialty. By leveraging our vivarium we can perform your in vivo studies and then analyze samples using the serology assays that we have developed for your project, ensuring a consistent and cost effective process. Assays are developed using best practices that will allow them to be adapted for GLP use in the future. IBT Bioservices can source or develop the critical reagents necessary for your assays.

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Bacterial Infection Animal Models
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The following infection models have been developed in-house by our scientists: Staphylococcus aureus pneumonia, Staph. aureus sepsis, Staph. and Strep. toxic shock, Enterotoxigenic E. coli intestinal colonization, Streptococcus pneumonia pneumonia.

The following infection models have been developed in-house by our scientists: Staphylococcus aureus pneumonia, Staph. aureus sepsis, Staph. and Strep. toxic shock, Enterotoxigenic E. coli intestinal colonization, Streptococcus pneumonia pneumonia.

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Biomarker Analysis
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Cytokine and Biomarker Analysis. Using a highly sensitive electrochemiluminescence technology developed by Meso Scale Discovery ™ IBT Bioservices offers custom services for testing cytokines, chemokines and other biomarkers in culture supernatants and sera. MSD is a revolutionary technology that utilizes electrochemiluminescence... Show more »

Cytokine and Biomarker Analysis. Using a highly sensitive electrochemiluminescence technology developed by Meso Scale Discovery ™ IBT Bioservices offers custom services for testing cytokines, chemokines and other biomarkers in culture supernatants and sera. MSD is a revolutionary technology that utilizes electrochemiluminescence to detect binding events on patterned arrays. The combination forms a unique solution offering sensitivity (sub-picogram), dynamic range (10^3 to 10^4), and convenience (3 hours). MSD assays can be multiplexed up to 10 antigens per well.

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Cytokine Analysis
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IBT Bioservices offers custom services for testing cytokines, chemokines and other biomarkers in culture supernatants and sera. Assays can be multiplexed up to 10 antigens per well.

Cytokine and Biomarker Analysis. Using a highly sensitive electrochemiluminescence technology developed by Meso Scale Discovery ™ IBT Bioservices... Show more »

IBT Bioservices offers custom services for testing cytokines, chemokines and other biomarkers in culture supernatants and sera. Assays can be multiplexed up to 10 antigens per well.

Cytokine and Biomarker Analysis. Using a highly sensitive electrochemiluminescence technology developed by Meso Scale Discovery ™ IBT Bioservices offers custom services for testing cytokines, chemokines and other biomarkers in culture supernatants and sera. MSD is a revolutionary technology that utilizes electrochemiluminescence to detect binding events on patterned arrays. The combination forms a unique solution offering sensitivity (sub-picogram), dynamic range (10^3 to 10^4), and convenience (3 hours). MSD assays can be multiplexed up to 10 antigens per well.

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ELISA
Enzyme-linked immunosorbent assay
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In vitro Immunogenicity Assays
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Immunogenicity assays for vaccines and biologics are our specialty.

Immunogenicity assays for vaccines and biologics are our specialty.

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In vivo Immunogenicity Assays
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Immunogenicity assays for vaccines and biologics are our specialty.

Immunogenicity assays for vaccines and biologics are our specialty.

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Minimal Bactericidal Concentration (MBC) Assay
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A PhD scientist will oversee antibiotic testing for disc diffusion, minimum inhibitory concentration (MIC), minimal bactericidal concentration (MBC), and minimal doubling time/growth curve (MDT). Bacteria currently available for testing include Methicillin-Sensitive Staph. aureus (MSSA), Methicillin-Resistant Staph. aureus (MRSA),... Show more »

A PhD scientist will oversee antibiotic testing for disc diffusion, minimum inhibitory concentration (MIC), minimal bactericidal concentration (MBC), and minimal doubling time/growth curve (MDT). Bacteria currently available for testing include Methicillin-Sensitive Staph. aureus (MSSA), Methicillin-Resistant Staph. aureus (MRSA), Pseudomonas aeruginosa, Acinetobacter baumannii, Enterobacter aerogenes, Enterobacter cloacae, Streptococcus pneumonia, and Moraxella catarrhalis.

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Minimal Doubling Time/Growth Curve
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A PhD scientist will oversee antibiotic testing for disc diffusion, minimum inhibitory concentration (MIC), minimal bactericidal concentration (MBC), and minimal doubling time/growth curve (MDT). Bacteria currently available for testing include Methicillin-Sensitive Staph. aureus (MSSA), Methicillin-Resistant Staph. aureus (MRSA),... Show more »

A PhD scientist will oversee antibiotic testing for disc diffusion, minimum inhibitory concentration (MIC), minimal bactericidal concentration (MBC), and minimal doubling time/growth curve (MDT). Bacteria currently available for testing include Methicillin-Sensitive Staph. aureus (MSSA), Methicillin-Resistant Staph. aureus (MRSA), Pseudomonas aeruginosa, Acinetobacter baumannii, Enterobacter aerogenes, Enterobacter cloacae, Streptococcus pneumonia, and Moraxella catarrhalis.

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Minimum Inhibitory Concentration (MIC) Assay
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A PhD scientist will oversee antibiotic testing for disc diffusion, minimum inhibitory concentration (MIC), minimal bactericidal concentration (MBC), and minimal doubling time/growth curve (MDT). Bacteria currently available for testing include Methicillin-Sensitive Staph. aureus (MSSA), Methicillin-Resistant Staph. aureus... Show more »

A PhD scientist will oversee antibiotic testing for disc diffusion, minimum inhibitory concentration (MIC), minimal bactericidal concentration (MBC), and minimal doubling time/growth curve (MDT). Bacteria currently available for testing include Methicillin-Sensitive Staph. aureus (MSSA), Methicillin-Resistant Staph. aureus (MRSA), Pseudomonas aeruginosa, Acinetobacter baumannii, Enterobacter aerogenes, Enterobacter cloacae, Streptococcus pneumonia, and Moraxella catarrhalis.

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Serological Assays
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Vaccine Testing Services
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The scientists at IBT Bioservices have over 50 years of cumulative experience with vaccine studies in rodents and have formed strong relationships with government agencies and industry partners validating our experience. Our clients benefit from comprehensive sample collection capabilities including blood, tissue, and mucosal... Show more »

The scientists at IBT Bioservices have over 50 years of cumulative experience with vaccine studies in rodents and have formed strong relationships with government agencies and industry partners validating our experience. Our clients benefit from comprehensive sample collection capabilities including blood, tissue, and mucosal samples as needed. Samples can either be sent to your laboratory for further analysis or analyzed in our laboratories for pathogen-specific cellular and humoral immune responses or induction of cytokines and other biomarkers. Dosing routes available include intranasal, intragastric, subcutaneous, intramuscular, intraperitoneal, and intravenous.

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Viral Infection Animal Models
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The following infection models have been developed in-house by our scientists: Chikungunya, Venezuelan Equine Encephalitis, Dengue 2, Influenza H1N1, Influenza H3N2, Influenza B, Vaccinia, Cowpox. The new Dengue 2 model of hemorrhagic fever displays unique and powerful similarity to the disease progression observed in humans,... Show more »

The following infection models have been developed in-house by our scientists: Chikungunya, Venezuelan Equine Encephalitis, Dengue 2, Influenza H1N1, Influenza H3N2, Influenza B, Vaccinia, Cowpox. The new Dengue 2 model of hemorrhagic fever displays unique and powerful similarity to the disease progression observed in humans, making it particularly useful for drug and vaccine development.

VIral Infection Models:
Flaviviridae
Orthomyxoviridae
Poxviridae
Paramyxoviridae

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Project and Process Management
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Experimental Design
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Animal Models and Studies
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Animal Models of Disease
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Infectious Disease Animal Models
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Clinical Research
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Clinical Laboratory Services
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Clinical Hematology
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Biology
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Cells and Tissues
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Cytometry
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Microbiology Services
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Antimicrobial Activity Testing
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Virology Services
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Viral Assays
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Biochemistry & Molecular Biology
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Protein Services
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Protein Quantification
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Pharmacology & Toxicology
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Immunoassays
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Toxicology
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In vivo Toxicity Testing
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Bioanalysis
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Biomarkers
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Drug Discovery & Development
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Drug Discovery
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Vaccines
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