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HistoBridge

Hillsborough, New Jersey, US

HistoBridge LLC provides consulting services and execution in tissue biomarker development, histopathology, immunohistochemistry, and image analysis for drug discovery and development covering multiple therapeutic areas, including cardiovascular disease, diabetes, NASH, chronic kidney disease, fibrosis, muscular dystrophy/atrophy, infectious disease, neuroscience, and oncology.

Our pledge is to be your complete partner to achieve your scientific, regulatory, and commercial goals.

HistoBridge has not listed any services.

Pathology Reports
Price on request

Expert Pathologist Assessment

 Proving inputs for study design
 Scoring paradigms
 Result interpretation and reporting

Expert Pathologist Assessment

 Proving inputs for study design
 Scoring paradigms
 Result interpretation and reporting

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Histopathology Consulting
Price on request

Histopathology is the “gold standard” for the evaluation of cellular and tissue changes associated with a disease process or genetic defect. Routine sections are stained with hematoxylin and eosin, and a variety of other stains are commonly used to highlight various features or cell types.

Histobridge offers... Show more »

Histopathology is the “gold standard” for the evaluation of cellular and tissue changes associated with a disease process or genetic defect. Routine sections are stained with hematoxylin and eosin, and a variety of other stains are commonly used to highlight various features or cell types.

Histobridge offers scientific/technical consultation, including:

  • Protocols/Experimental Design
    • Preparation/review.
  • In-Life Phase
    • Monitoring and data analysis/interpretation.
  • Histopathology
    • Examination and interpretation of findings.
  • Pathology Reports
    • Preparation/review.
  • General Study Reports
    • Preparation/review.
  • Peer Review (Independent Party Opinion)
    • Of all phases of studies.
  • Quality Assurance/GLP Compliance
    • Of all phases of studies.
  • Toxicology Summaries/Executive Summaries/Drug Resumes/Manuscripts
    • Preparation/review.
  • Documents for Regulatory Submission (INDs, NDAs, PLAs, etc.)
    • Preparation/review.
  • Client Representation
    • At regulatory agencies, contract research organizations, etc.
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Immunohistochemistry (IHC)
Price on request

We currently provide high quality immunohistochemical staining:

  • High quality IHC staining: Using standard protocols developed in-house or provided by the client.
    • Paraffin-embedded human or rodent tissue blocks or unstained slide
    • OCT-embedded human or rodent frozen tissue blocks or unstained slides
  • Optimizing IHC... Show more »

We currently provide high quality immunohistochemical staining:

  • High quality IHC staining: Using standard protocols developed in-house or provided by the client.
    • Paraffin-embedded human or rodent tissue blocks or unstained slide
    • OCT-embedded human or rodent frozen tissue blocks or unstained slides
  • Optimizing IHC protocol: we optimize IHC protocols for primary antibodies that are commercially available or supplied by the client.
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Special Slide Staining
Price on request

We currently provide the following special stains:

  • Masson's Trichrome: To demonstrate the differentiation between collagen and smooth muscle in tumors and identify increases in collagenous tissue in diseases.
  • Oil Red O: To demonstrate neutral lipids in frozen tissue section; can only be performed on frozen tissue... Show more »

We currently provide the following special stains:

  • Masson's Trichrome: To demonstrate the differentiation between collagen and smooth muscle in tumors and identify increases in collagenous tissue in diseases.
  • Oil Red O: To demonstrate neutral lipids in frozen tissue section; can only be performed on frozen tissue sections.
  • PAS: A stain to detect polysaccharides, neutral mucosubstances & basement membranes.
  • Picrosirius Red: To visualize collagen I and III fibers in addition to muscle in tissue sections. The PSR stain may be viewed using standard light microscopy or polarized light resulting in birefringence of the collagen fibers to distinguish between type I and type III.
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Image Analysis
Price on request

We currently provide digital slide scanning and image analysis using ImageScope or Image J.

We currently provide digital slide scanning and image analysis using ImageScope or Image J.

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Histological Staining
Price on request
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Immunocytochemistry
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Histopathological Examination
Price on request

Extensive experience in cardiometabolic diseases therapeutic area such as chronic kidney disease/diabetic nephropathy, NASH, heart failure/hypertension, fibrosis, etc.

Extensive experience in cardiometabolic diseases therapeutic area such as chronic kidney disease/diabetic nephropathy, NASH, heart failure/hypertension, fibrosis, etc.

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Data Analysis and Management
Price on request
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Protein Expression Visualization
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Clinical Research
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Protein Services
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Biology
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Immunostaining
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Clinical Laboratory Services
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Clinical and Anatomic Pathology
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Computational & Statistical Analysis
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Biochemistry & Molecular Biology
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2018-02-02 15:34:47 -0500

Net Promoter Score of 8 received for Histological Staining.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 8.

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