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HistoBridge

ic 9.2/10 Overall Rating 100% Positive
ic 22 Orders Completed
Hillsborough, New Jersey, US

About HistoBridge

HistoBridge LLC provides consulting services and execution in tissue biomarker development, histopathology, immunohistochemistry, and image analysis for drug discovery and development covering multiple therapeutic areas, including cardiovascular disease, diabetes, NASH, chronic kidney disease, fibrosis,... Show more »

HistoBridge LLC provides consulting services and execution in tissue biomarker development, histopathology, immunohistochemistry, and image analysis for drug discovery and development covering multiple therapeutic areas, including cardiovascular disease, diabetes, NASH, chronic kidney disease, fibrosis, muscular dystrophy/atrophy, infectious disease, neuroscience, and oncology.

Our pledge is to be your complete partner to achieve your scientific, regulatory, and commercial goals.

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Our Services (20)


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Antibody Characterization

Price on request
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Pathology Reports

Price on request

Expert Pathologist Assessment

 Proving inputs for study design
 Scoring paradigms
 Result interpretation and reporting

Expert Pathologist Assessment

 Proving inputs for study design
 Scoring paradigms
 Result interpretation and reporting

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Histopathology Consulting

Price on request

Histopathology is the “gold standard” for the evaluation of cellular and tissue changes associated with a disease process or genetic defect. Routine sections are stained with hematoxylin and eosin, and a variety of other stains are commonly used to highlight various features or cell types.

Histobridge offers... Show more »

Histopathology is the “gold standard” for the evaluation of cellular and tissue changes associated with a disease process or genetic defect. Routine sections are stained with hematoxylin and eosin, and a variety of other stains are commonly used to highlight various features or cell types.

Histobridge offers scientific/technical consultation, including:

  • Protocols/Experimental Design
    • Preparation/review.
  • In-Life Phase
    • Monitoring and data analysis/interpretation.
  • Histopathology
    • Examination and interpretation of findings.
  • Pathology Reports
    • Preparation/review.
  • General Study Reports
    • Preparation/review.
  • Peer Review (Independent Party Opinion)
    • Of all phases of studies.
  • Quality Assurance/GLP Compliance
    • Of all phases of studies.
  • Toxicology Summaries/Executive Summaries/Drug Resumes/Manuscripts
    • Preparation/review.
  • Documents for Regulatory Submission (INDs, NDAs, PLAs, etc.)
    • Preparation/review.
  • Client Representation
    • At regulatory agencies, contract research organizations, etc.
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Immunohistochemistry (IHC)

Price on request

We currently provide high quality immunohistochemical staining:

  • High quality IHC staining: Using standard protocols developed in-house or provided by the client.
    • Paraffin-embedded human or rodent tissue blocks or unstained slide
    • OCT-embedded human or rodent frozen tissue blocks or unstained slides
  • Optimizing IHC... Show more »

We currently provide high quality immunohistochemical staining:

  • High quality IHC staining: Using standard protocols developed in-house or provided by the client.
    • Paraffin-embedded human or rodent tissue blocks or unstained slide
    • OCT-embedded human or rodent frozen tissue blocks or unstained slides
  • Optimizing IHC protocol: we optimize IHC protocols for primary antibodies that are commercially available or supplied by the client.
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Special Slide Staining

Price on request

We currently provide the following special stains:

  • Masson's Trichrome: To demonstrate the differentiation between collagen and smooth muscle in tumors and identify increases in collagenous tissue in diseases.
  • Oil Red O: To demonstrate neutral lipids in frozen tissue section; can only be performed on frozen tissue... Show more »

We currently provide the following special stains:

  • Masson's Trichrome: To demonstrate the differentiation between collagen and smooth muscle in tumors and identify increases in collagenous tissue in diseases.
  • Oil Red O: To demonstrate neutral lipids in frozen tissue section; can only be performed on frozen tissue sections.
  • PAS: A stain to detect polysaccharides, neutral mucosubstances & basement membranes.
  • Picrosirius Red: To visualize collagen I and III fibers in addition to muscle in tissue sections. The PSR stain may be viewed using standard light microscopy or polarized light resulting in birefringence of the collagen fibers to distinguish between type I and type III.
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Image Analysis

Price on request

We currently provide digital slide scanning and image analysis using ImageScope or Image J.

We currently provide digital slide scanning and image analysis using ImageScope or Image J.

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Histological Staining

Price on request
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Clinical and Anatomic Pathology

Price on request
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Computational Modeling

Price on request
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Protein Expression Visualization

Price on request
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Data Services

Price on request
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Immunostaining

Price on request
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Protein Services

Price on request
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Clinical Laboratory Services

Price on request
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Clinical Research

Price on request
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Antibody Services

Price on request

Antibody Services

Antibody Services

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Immunocytochemistry

Price on request
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Histopathological Examination

Price on request

Extensive experience in cardiometabolic diseases therapeutic area such as chronic kidney disease/diabetic nephropathy, NASH, heart failure/hypertension, fibrosis, etc.

Extensive experience in cardiometabolic diseases therapeutic area such as chronic kidney disease/diabetic nephropathy, NASH, heart failure/hypertension, fibrosis, etc.

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Biology

Price on request
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Biochemistry & Molecular Biology

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  • Positive review for Pathology Reports:

    October 2018

    "The work done by HistoBridge has met our criteria on data quality and data turnaround time."

  • Positive review for Histological Staining:

    August 2018

    "HistoBridge was very good at keeping me posted on the status of the experiments. We worked together to make the best decisions moving forward for the project. They finished the project in a very timely manner. I would definitely use them again."

HistoBridge has not received any endorsements.