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National Crystallization Center

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Buffalo, New York, US

About National Crystallization Center

The National Crystallization Center at HWI performs crystal-growth screening experiments for both soluble and membrane biological macromolecules. www.getacrystal.org

Our Services (4)


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Protein Crystallization Screening and Optimization

Price on request

Experimental screening 1,536 different chemical cocktails to find initial crystallization conditions for both soluble and membrane biological macromolecules.  Each condition is monitored with a robust imaging schedule using brightfield, SHG, and UV-TPEF imaging methods to quickly identify potential crystallization hits.  A major bottleneck in macromolecular crystallography remains identifying conditions to generate diffraction-quality crystals. The National Crystallization Center at HWI has been at the forefront of developing high-throughput crystallization methodology. Using patented technologies uniquely available at the National Crystallization Center allows for rapid, efficient screening and identification of crystal growth conditions.

crystallization screening protein crystallization X-ray crystallography structural biology Formulatrix Rock Imager 1000 with SONICC

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Crystallization Services

Price on request
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Iterative Crystallization

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Co-Crystallization

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