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GenScript USA Inc

254 Orders Completed
Piscataway Township, New Jersey, US

About GenScript USA Inc

Founded: 2002 Type: Public Company Size: 1001-5000 employees

GenScript is the leading gene, peptide, protein and antibody research partner for fundamental life science research, translational biomedical research, and early stage pharmaceutical development. Since our establishment in 2002, GenScript has exponentially grown to become a global leading biotech company that... Show more »

GenScript is the leading gene, peptide, protein and antibody research partner for fundamental life science research, translational biomedical research, and early stage pharmaceutical development. Since our establishment in 2002, GenScript has exponentially grown to become a global leading biotech company that provides life sciences services and products to scientists over 100 countries worldwide. During our tenure we have built the best-in-class capacity and capability for biological research services encompassing gene synthesis and molecular biology, peptide synthesis, custom antibodies, protein expression, antibody and protein engineering, and in vitro and in vivo pharmacology – all with the goal to Make Research Easy.

Key Facts about GenScript

  • Peer-Reviewed Citations – GenScript is the frequently cited biotech company in the world. More than 12,000 papers cite the service and products from GenScript.
  • Gene synthesis – one of the largest gene synthesis capacity in the world with > 100 million bp/month; record length 50 kb; turnaround time as short as 4 business days.
  • Peptide synthesis – 6,000/month; record length over 100 aa.
  • Antibody services – 6,000 rabbits and 12,000 rodents; pAb/mAb in 45 days; guaranteed immune response & amount.
  • Protein expression – 4 major expression systems (bacterial, mammalian, yeast, insect); guaranteed purified protein.
  • Animal model services – 4 key in vivo pharmacological services: in vivo drug efficacy evaluation, pharmacokinetic studies, toxicity assessment, and biomarker & bioanalysis services.

We strive with competence and confidence to meet your demand for developing pre-clinical drug candidates time-efficiently and cost-effectively. With track performance record, GenScript is your ideal and reliable innovation partner in drug discovery.

Recent Citations

  • Xin Fang, Chi Zhang. Detection of adulterated murine components in meat products by TaqMan© real-time PCR. Food Chem. 2016 Feb;192(1);485-490.
  • Sooman L, Wennman A, Hamberg M, Hoffmann I, Oliw EH. Replacement of two amino acids of 9R-dioxygenase-allene oxide synthase of Aspergillus niger inverts the chirality of the hydroperoxide and the allene oxide. Biochim Biophys Acta. 2016 Feb;1861(2);108-18.
  • Parinyaporn Nuurai, Scott F. Cummins , Natasha A. Botwright, Prasert Sobhon. Characterization of an abalone gonadotropin-releasing hormone and its effect on ovarian cell proliferation. Aquaculture. 2016 Jan;116C122.
  • Chen Huana, Li Jianga, Xiujuan Ana, Ruoyi Kanga, Mingliang Yub, Ruijuan Mab, Zhifang Yua. Potential role of glutathione peroxidase gene family in peach fruit ripening under combined postharvest treatment with heat and 1-MCP. Postharvest Biol Technol. 2016 Jan;175C184.
  • Shawn Pugh, Rebekah McKenna, Ibrahim Halloum, David R. Nielsen. Engineering Escherichia coli for renewable benzyl alcohol production. Metab Eng Commun. 2015 Dec;39-45.
  • Chamila Nimalaratne, Nandika Bandara, Jianping Wu. Purification and Characterization of Antioxidant Peptides from Enzymatically Hydrolyzed Chicken Egg White. Food Chem. 2015 Dec;188(1);467C472.
  • Sarah Usher, Richard P. Haslam, Noemi Ruiz-Lopez, Olga Sayanova, Johnathan A. Napier. Field trial evaluation of the accumulation of omega-3 long chain polyunsaturated fatty acids in transgenic Camelina sativa: Making fish oil substitutes in plants. Metab Eng Commun. 2015 Dec;93-98.
  • Humphries J, Harter B. Identification of nuclear factor kappaB (NF-κB) binding motifs in Biomphalaria glabrata. Dev Comp Immunol. 2015 Dec;53(2);366-70.
  • GÓmez-Rojo EM, Romero-Santacreu L, Jaime I, Rovira J. A novel real-time PCR assay for the specific identification and quantification of Weissella viridescens in blood sausages. Int J Food Microbiol. 2015 Dec;16-24.
  • Kwon Y, Yang YJ, Jung D, Hwang BH, Cha HJ. Biomimetic repeat protein derived from Xenopus tropicalis for fibrous scaffold fabrication. Biopolymers. 2015 Dec;103(12);659-64.
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Certifications & Qualifications

AAALAC OLAW

Our Services (92)


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In vivo Electrophysiology

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Ex vivo Electrophysiology

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Animal Immunization for Antibody Production

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Rabbit Goat Chicken Mouse Rat

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Antibody Characterization

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Homology Modeling

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Antibody Screening

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Phage Display Library Construction and Screening

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Bioanalysis

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Antibody Humanization

Price on request

Antibody humanization is the process to replace non-human frameworks of a non-human (usually) mAb with human ones. The key for a successful humanization is to maintain the affinity of the antibody while replacing the residues. GenScript’s unique antibody humanization service combines CDR-grafting, library-based proprietary... Show more »

Antibody humanization is the process to replace non-human frameworks of a non-human (usually) mAb with human ones. The key for a successful humanization is to maintain the affinity of the antibody while replacing the residues. GenScript’s unique antibody humanization service combines CDR-grafting, library-based proprietary ‘framework assembly’ method (US20120316085 (A1)) and FASEBA screening (FAst Screening for Expression level, Biophysical properties, and Affinities). The antibody can be humanized and at the same time engineered for better properties like expression level and thermostability.

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Lentivirus Production

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ADCC and CDC Assays

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Antibody therapy has been proven to be highly powerful for cancer treatment. Two important mechanisms used by antibody drugs to kill targeted tumor cells are Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC), and Complement Dependent Cytotoxicity (CDC). GenScript is pleased to present to you a recombinant effector cell-based... Show more »

Antibody therapy has been proven to be highly powerful for cancer treatment. Two important mechanisms used by antibody drugs to kill targeted tumor cells are Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC), and Complement Dependent Cytotoxicity (CDC). GenScript is pleased to present to you a recombinant effector cell-based assay. The readout is endpoint-driven (target cell lysis). The consistency of results is dramatically enhanced compared to PBMC-based ADCC assay. The turnaround time and the cost are both significantly reduced by replacing primary cells with recombinant cells as the source of effector cells. The key to GenScript's breakthough in ADCC is the development of a NK92 cell line expressing FcRγ3a (CD16a)*. If desired, a PBMC-based ADCC assay is also available.

The CDC assay uses normal human serum as the source of complement. By implementing strict QC standards, GenScript can provide the assurance of the efficacy and potency profiles of your therapeutic antibodies.

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Cell Line Generation

Price on request

Stable cell lines are used in a variety of research applications such as recombinant protein and antibody production, assay development, gene editing, functional studies and more. At GenScript, we offer comprehensive stable cell line development capabilities that either begin with DNA provided by our clients or that are powered by... Show more »

Stable cell lines are used in a variety of research applications such as recombinant protein and antibody production, assay development, gene editing, functional studies and more. At GenScript, we offer comprehensive stable cell line development capabilities that either begin with DNA provided by our clients or that are powered by our fast, high efficiency gene synthesis service that seamlessly integrates all steps of stable cell line generation, delivering high quality stable clones of your choice. Boost your productivity and improve your results by leveraging GenScript's top quality stable cell line services.

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Custom Polyclonal Antibody Production

Price on request

GenScript offers a full suite of high quality custom polyclonal antibody production services designed with your needs in mind. Since 2004, our team has produced over 12,000 high quality custom polyclonal antibodies from rabbit,mouse, rat, goat and chicken hosts. The PolyExpress™ Premium protein immunization packages carry an... Show more »

GenScript offers a full suite of high quality custom polyclonal antibody production services designed with your needs in mind. Since 2004, our team has produced over 12,000 high quality custom polyclonal antibodies from rabbit,mouse, rat, goat and chicken hosts. The PolyExpress™ Premium protein immunization packages carry an industry leading guarantee of positive Western blot and 1:64,000 ELISA titer. PolyExpress™ Basic, Silver, and Gold peptide immunization packages also carry the ELISA titer guarantee and can deliver your custom pAb in 45 days.

Key Features of PolyExpress™ Custom Polyclonal Antibody Production Services

  • Optimize immunization: Our OptimumAntigen™ design tool and intelligent Antigen Strategy increase specificity and affinity of antibodies.
  • Certified facility: AAALAC International accreditation and OLAW certification, demonstrating our commitment to responsible animal care and use.
  • Guaranteed results: purified custom polyclonal antibodies 1-5 mg/antigen, and an ELISA titer of 1:64,000.
  • Fast turnaround time: delivery of purified custom polyclonal antibodies in 45 days.
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Protein Expression in Yeast

Price on request

Yeast fermentation is the most economical eukaryotic expression system for scale up production of both secreted and intracellular proteins that require post-translational modifications, including humanized antibodies. GenScript's YeastHIGH™ yeast fermentation and expression services utilize a proprietary yeast fermentation... Show more »

Yeast fermentation is the most economical eukaryotic expression system for scale up production of both secreted and intracellular proteins that require post-translational modifications, including humanized antibodies. GenScript's YeastHIGH™ yeast fermentation and expression services utilize a proprietary yeast fermentation technology for high-yield and high quality recombinant protein production in yeast, by selecting stable and durable production yeast strains that resemble mammalian system the most. We are also equipped with scale-up yeast fermentation capacity up to 500 liters. In addition, as the largest gene synthesis supplier in the U.S., GenScript deploys free OptimumGene™ codon optimization specific to yeast strains such as Pichia pastoris and Saccharomyces cerevisiae to further enhance your recombinant protein yields.

Advantages of YeastHIGH™ yeast fermentation and expression services

  • Using proprietary technology: GenScript's YeastHIGH™ technology takes consideration of all essential parameters for high-level recombinant protein production in yeast fermentation, including promoters, optimal vector copies per cell, inducibility, signal peptides and cellular location etc., ensuring high yield and high quality protein production in yeast cells
  • Large-scale protein production capacity: GenScript is not only equipped with yeast fermentation capacity up to 500L, but also has large-scale filtration system to enhance recombinant protein purity and yields
  • Streamlined services: GenScript can take your project directly from gene synthesis, to recombinant protein expression, as well as downstream application development, such as antibody production and assay development
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Pichia pastoris

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Custom Peptide Arrays

Price on request

GenScript offers an extremely quick and cost-efficient custom peptide array service to assist in your drug development research. Based on our advanced peptide array platform, we can also provide comprehensive downstream services such as eptiope mapping. If you need up to a milligram or more purified peptide (purity up to 95%) for... Show more »

GenScript offers an extremely quick and cost-efficient custom peptide array service to assist in your drug development research. Based on our advanced peptide array platform, we can also provide comprehensive downstream services such as eptiope mapping. If you need up to a milligram or more purified peptide (purity up to 95%) for epitope mapping, activity assays, or proteomic applications, view our rapid, high-throughput peptide library services.

For further efficiency and convenience, GenScript provides an instant online quotation system for peptide array services. In addition, GenScript provides six, free online peptide library/array design tools to help you generate different peptide arrays to assist your research design.

Key Features

  • No cross-contamination: Peptide synthesis is performed by automated instrumentation.
  • Comprehensive modifications: Including biotin, FITC, phosphorylation, and more.
  • Stringent quality control: MS QC on 5% of peptide, and Certificate of Analysis report.
  • Instant online quotation: Convenient online quotation for your peptide array requests.
  • One-stop downstream services: Epitope mapping service, binding assay, and functional assays for your drug discovery research.

Applications

  • Antibody epitope mapping
  • Protein-protein, enzyme-substrate, and receptor-ligand interactions studies
  • Phosphorylation studies
  • Binding and functional assay studies
  • B-cell epitope mapping
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Peptide Libraries

Price on request

A peptide library is a systematic combination of a large number of different peptides widely used for protein-related studies. Peptide libraries are in ever increasing demand due to the expanding interest in peptide drug and vaccine development, immunotherapy, and proteomics. To accelerate your research, GenScript offers two... Show more »

A peptide library is a systematic combination of a large number of different peptides widely used for protein-related studies. Peptide libraries are in ever increasing demand due to the expanding interest in peptide drug and vaccine development, immunotherapy, and proteomics. To accelerate your research, GenScript offers two peptide library services:

  • Standard peptide library: milligram level quantities and a wide range of purities for many research applications
  • Micro-scale peptide library: microgram quantities at reduced prices, ideal for preliminary screens or proteomics applications

To make your research easier, GenScript also offers extensive QC for any peptide library order. As a part of the AccuPep QC service, you can request TFA removal, solubility testing, endotoxin analysis, or other services to ensure that your peptide library will meet your intended research application. In addition, our proprietary FlexPeptide™ technology ensures that hundreds of peptides can be synthesized at the lowest cost possible.

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Custom Monoclonal Antibody (mAb) Production

Price on request

Our technical account managers, all with PhDs, will help you custom design the optimal protocol to meet your specific requirements. With GenScript's fully custom monoclonal antibody generation services, you are in control of every stage, deciding how to respond to results mid-project. You can evaluate and modify your approach,... Show more »

Our technical account managers, all with PhDs, will help you custom design the optimal protocol to meet your specific requirements. With GenScript's fully custom monoclonal antibody generation services, you are in control of every stage, deciding how to respond to results mid-project. You can evaluate and modify your approach, restart an entire phase, or terminate the project if you are not completely satisfied. Don't risk commitment of time and money to a rigid protocol when our fully custom monoclonal antibody generation service offers the ultimate flexibility. Partnering with GenScript's years of expertise can help you find success in your custom antibody development.

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Hybridoma Development

Price on request

Hybridoma development is a powerful approach and the critical path to antibody drug lead generation. With 12 years’ experience in custom antibody production, GenScript has established a comprehensive antibody drug discovery platform under the leadership of the pioneers in the antibody drug discovery field. GenScript’s Premium... Show more »

Hybridoma development is a powerful approach and the critical path to antibody drug lead generation. With 12 years’ experience in custom antibody production, GenScript has established a comprehensive antibody drug discovery platform under the leadership of the pioneers in the antibody drug discovery field. GenScript’s Premium Hybridoma Development Services utilize a portfolio of immunization approaches, including protein, whole cells and DNA immunization, high throughput binder screening and series of functional screening assays to generate up to 100 high quality hybridoma clones, assuring the success of your antibody drug development at the very beginning.

Key Features of Premium Hybridoma Development Services

  • Full spectrum of immunization approaches: protein, peptide, whole cells and DNA immunization
  • One stop solution: from antigen production to hybridoma development and characterization
  • High throughput screening: Proprietary NativeSelect™ ELISA or HT March™ for high efficiency screening
  • Comprehensive functional assay: Validated functional assay platforms provide reliable in vitro screening
  • Readily integrated downstream services: Ab sequencing, Ab humanization, rAb production and anti-idiotype antibodies for your Ab drug PD/PK studies.
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Hybridoma Stabilization

Price on request

Antibody production by hybridoma cell lines is inherently unstable. Failure to maintain cell lines properly will lead to loss in antibody productivity and eventually the cell line itself. Traditionally, hybridoma stabilization refers to the selection of stable clones for extended stable expression but the problem still remains. By... Show more »

Antibody production by hybridoma cell lines is inherently unstable. Failure to maintain cell lines properly will lead to loss in antibody productivity and eventually the cell line itself. Traditionally, hybridoma stabilization refers to the selection of stable clones for extended stable expression but the problem still remains. By integrating antibody engineering and bioprocess development technology, GenScript's Hybridoma Stabilization Service (Cat. No.: SC1511) can redesign the antibody for permanent preservation and improved productivity with advanced Hybridoma Revival System, and solve the inherent defect of antibody generation by hybridoma.

Key Features

  • Stability test of generated clones
  • Free selection of original or novel Fc for your antibody
  • Stable and high productivity of desired antibody
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Epitope Mapping

Price on request

Epitope mapping has become more and more vital in both vaccine and antibody drug development. Knowledge on epitope of an antibody will largely facilitate your drug design and patent application. Based on our advanced peptide library platform, GenScript provides a comprehensive series of Epitope Mapping Services (Cat. No: SC1500)... Show more »

Epitope mapping has become more and more vital in both vaccine and antibody drug development. Knowledge on epitope of an antibody will largely facilitate your drug design and patent application. Based on our advanced peptide library platform, GenScript provides a comprehensive series of Epitope Mapping Services (Cat. No: SC1500) to fulfill customers' demand.

Key Features

  • Advanced technology: Proprietary FlexPeptide™ technology ensures quality
  • Unparalleled accuracy: Minimized unspecific interactions by optimized detection methods
  • Comprehensive services: One-stop services to map various epitopes
  • In house peptide library synthesis and assay development
  • Fast delivery: Delivery starting from 4 weeks
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Antibody Sequencing

Price on request

Knowing the sequence of your monoclonal antibody is not only the first step towards antibody engineering and function optimization, but also critical for patent application. GenScript's advanced technology offers fast and professional sequencing services for your hard-won monoclonal antibodies. We are capable of sequencing most... Show more »

Knowing the sequence of your monoclonal antibody is not only the first step towards antibody engineering and function optimization, but also critical for patent application. GenScript's advanced technology offers fast and professional sequencing services for your hard-won monoclonal antibodies. We are capable of sequencing most antibodies with customer-selected specifications (see below for a list of different specifications). You can rely on our ISO 9001 certified Antibody Sequencing Service (Cat. No.: SC1408) to speed and facilitate your patent application, database banking, and therapeutic antibody development.

Top 3 pitfalls to avoid when sequencing antibodies

  • Impurity of hybridoma cells: Hybridomas may contain pseudogenes and mRNAs encoding non-functional antibodies, which may be amplified by primer pairs intended to clone the target antibody.
  • GenScript will sequence 5 independent clones for each chain, to ensure accuracy.
  • Mutations introduced by PCR: During the amplification of the cDNA, the use of degenerate primer sets means there is the chance of mutagenesis.
  • GenScript always uses both 5'- and 3'- RACE (rapid amplification of cDNA ends) to ensure accuracy of amplified products.
  • GenScript always performs full length sequencing of the variable region, which ensures the accuracy of the sequence span, from leader sequence to the start of FR1 region.
  • Full sequence is inaccurate or misaligned: Once the individual sequences are obtained for each chain, they must be aligned properly to ensure the full sequence is accurate.
  • GenScript has sequenced over 1000 antibodies, our expertise ensures you will receive a 100% accurate sequence.

Key Features

  • Extreme accuracy by meticulous operation and strict quality control
  • Fast delivery, starting from 6 days
  • Competitive price, starting from $1200
  • Comprehensive services covering human, mouse, rat and rabbit mAbs
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CRISPR/Cas9 Genome Editing

Price on request

CRISPR/Cas9 genome editing has become widely used due to its simplicity and versatility, and CRISPR technology has been adapted for diverse applications aside from genome editing. As a leader in gene synthesis and genome editing, and through our partnership with Feng Zhang’s laboratory at the Broad Institute of MIT and Harvard*,... Show more »

CRISPR/Cas9 genome editing has become widely used due to its simplicity and versatility, and CRISPR technology has been adapted for diverse applications aside from genome editing. As a leader in gene synthesis and genome editing, and through our partnership with Feng Zhang’s laboratory at the Broad Institute of MIT and Harvard*, GenScript offers validated CRISPR products, services and resources to help you harness the power of CRISPR genome editing for your research. Learn more about our CRISPR services – including gRNA database, CRISPR plasmids for genome editing, SAM constructs for Cas9-based activation of endogenous gene transcription, GeCKO and SAM libraries, mammalian cell line genome editing and microbial genome editing.

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Gene Synthesis

Price on request

As a pioneer and leader in gene synthesis technology, and the largest gene synthesis supplier in the US, GenScript has completed over 600,000 genes synthesis projects for scientists around the world. Gene synthesis enables powerful solutions for molecular cloning, creating fusion proteins, or achieving sufficiently high protein... Show more »

As a pioneer and leader in gene synthesis technology, and the largest gene synthesis supplier in the US, GenScript has completed over 600,000 genes synthesis projects for scientists around the world. Gene synthesis enables powerful solutions for molecular cloning, creating fusion proteins, or achieving sufficiently high protein expression levels. GenScript offers gene synthesis services with complete customizability and considerable savings of time and money compared to traditional molecular cloning using recombinant DNA technology.
Our experienced Ph.D.-level project managers ensure that you receive professional service tailored to your needs and on-time delivery of ISO 9001:2008 certified products with 100% sequence accuracy guaranteed.

Gene Length Starting Price * Starting Turnaround Time (business days) Minimum Order Size Codon Optimization
Custom Gene Synthesis Cat No. SC1010 ≤ 8kb Starts at $0.35/bp or minimum charge $159/gene 8 No minimum Optional (complimentary)
GenBrick™ Synthesis Cat No. SC1584 > 8 kb Starts at $0.45/bp 23 No minimum Optional (complimentary)
Rush Gene Synthesis Cat No. SC1575 ≤ 2 kb Request a quote 4 No minimum Optional (complimentary)
Fast Gene Synthesis Cat No. SC1619 ≤ 5 kb Request a quote 7 No minimum Optional (complimentary)
GenPlus™ HT Gene Synthesis Cat No. SC 1645 ≤10 kb Starts at $0.23/bp or $99/gene for orders ≥ 25 genes. 10-12 25 genes Optional (complimentary)
GenPlus™ Economy Gene Synthesis Cat No. SC1681 ≤10 kb $0.23/bp 15 No minimum Required (complimentary)
  • The prices and turnaround times here are estimates for non-complex genes. Price and turnaround increase as gene length and complexity increase. Please contact us to learn about discounted pricing for high-volume orders, institutional contracts, long-term partnerships, or to discuss your specific requirements. Be sure to check our current promotions.
  1. Downstream services, including cloning, mutagenesis. plasmid prep and protein expression evaluation, are available at additional cost.
  • Customers retain all rights to the sequence data and related intellectual property.

Advantages of Custom Gene Synthesis

  • Free codon optimization - Proprietary OptimumGene™ codon optimization technology can comprehensively optimize DNA sequences to significantly increase protein expression in any host.
  • Any gene in any vector - CloneEZ® seamless cloning technology can accurately and efficiently fuse your gene into any site on any vector.
  • Guaranteed sequence - Proprietary Gene-on-Demand® gene synthesis platform enables mutation-free DNA synthesis for genes of any length and any complexity.
  • One-stop solutions - Comprehensive downstream services can save you time on material transfer.
  • Cost effective - Ease your budget crunch with competitive prices supported by economy-of-scale.
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Antibody Purification

Price on request
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Bacterial Protein Expression

Price on request

Our BacPower™ Guaranteed Bacterial protein expression packages offer a comprehensive panel of options for your target protein production in an E. coli system with guaranteed protein amounts, purities, endotoxin levels and the option of producing tag-free proteins as well, to meet a variety of your research needs. You simply... Show more »

Our BacPower™ Guaranteed Bacterial protein expression packages offer a comprehensive panel of options for your target protein production in an E. coli system with guaranteed protein amounts, purities, endotoxin levels and the option of producing tag-free proteins as well, to meet a variety of your research needs. You simply provide protein sequence and we will deliver the protein (tagged or tag-free) at the amount and purity that you specified. All BacPower™ guaranteed bacterial protein expression packages start with our proprietary codon optimization service, followed by gene synthesis and sub cloning, all the way through protein expression and purification using our bacterial protein expression system. If your target recombinant protein becomes insoluble in the inclusion body fraction, FoldArt™, our proprietary protein refolding technology will be applied to solubilize the protein at no extra cost to you. This service is also ideal for the production of high quality protein antigens for antibody production. In case we fail on either the amount or purity as specified, there is no charge to you whatsoever.

Place your order today to experience unprecedented, high quality services yet competitive pricing, offered with our all of our Bacterial protein expression packages.

BacPower™ Guaranteed Bacterial protein Expression packages with unprecedented assurances

  • Gene synthesis is included in the package – no additional cost to you.
  • Guarantees the amount of custom recombinant protein – no cost to you if project fails.
  • Guarantees the purity of custom recombinant protein – no cost to you if desired purity is not achieved.
  • Competitive price - starting from $2,200.
  • Fast turnaround time - as little as 6 weeks.
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B. subtilis E. coli

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Human Biobanking

Price on request
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Apoptosis Assays

Price on request
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Custom Cell-Based Assay Development

Price on request

custom assays

custom assays

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DNA Sequencing

Price on request

As the largest gene synthesis and comprehensive molecular biology service provider in the USA with proven capability and reliability, GenScript now expands DNA sequencing services in North America to offer our customers high speed and superior quality services. The Sanger DNA sequencing services is performed by our professionally... Show more »

As the largest gene synthesis and comprehensive molecular biology service provider in the USA with proven capability and reliability, GenScript now expands DNA sequencing services in North America to offer our customers high speed and superior quality services. The Sanger DNA sequencing services is performed by our professionally trained staff on our state-of-the-art instrument and analyzed with advanced bioinformatics tools.

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DNA Synthesis and Probe Development

Starting at $0.35 per base

Requirements:
4 µg of lyophilized plasmid containing your gene insert
Sequence chromatograms covering your gene (electronic)
Construct map for the plasmid (electronic)
Quality assurance certificate

Requirements:
4 µg of lyophilized plasmid containing your gene insert
Sequence chromatograms covering your gene (electronic)
Construct map for the plasmid (electronic)
Quality assurance certificate

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High Throughput Screening (HTS)

Price on request
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Baculovirus/Insect Cell Protein Expression

Price on request

GenScript's BacuVance™ baculovirus expression system was developed by our in-house team of scientists for virus production and expression of recombinant proteins from baculovirus-infected insect cells. As the largest gene synthesis supplier in the U.S., GenScript can provide you with free, advanced codon optimization specific to... Show more »

GenScript's BacuVance™ baculovirus expression system was developed by our in-house team of scientists for virus production and expression of recombinant proteins from baculovirus-infected insect cells. As the largest gene synthesis supplier in the U.S., GenScript can provide you with free, advanced codon optimization specific to Sf9, Sf21, Hi-5, and S2 insect cell lines, to further enhance the expression of your protein.

There are several advantages of using baculovirus expression system over E. coli system, such as improved solubility, ability to incorporate post-translational modifications, and higher yields for secreted proteins. For customers who prefer a eukaryotic expression system, are exploring lower-cost alternatives to mammalian expression system but do not want to compromise on the overall quality of their recombinant protein, we strongly recommend considering our BacuVance™ baculovirus expression system. Using our baculovirus expression system we can establish the best possible protocol for your custom project and then scale up to get the highest expression of your target protein. Alternatively, if you are looking for a fail-safe option for insect protein production at a competitive price, visit the InsectPower™ guaranteed protein page to learn more.

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Hit to Lead and Lead Optimization

Price on request
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Protein Expression in Mammalian Cells

Mammalian cell based recombinant protein production
Price on request

Transient Expression Of Recombinant Protein & Antibody

GenScript transient mammalian expression service offers fast production and delivery of high quality recombinant proteins and monoclonal antibodies at competitive prices, from pilot scale to guaranteed production, up to gram quantities.

*Stable Cell Line... Show more »

Transient Expression Of Recombinant Protein & Antibody

GenScript transient mammalian expression service offers fast production and delivery of high quality recombinant proteins and monoclonal antibodies at competitive prices, from pilot scale to guaranteed production, up to gram quantities.

Stable Cell Line Development

GenScript comprehensive stable cell line development capabilities seamlessly integrate all steps of stable cell line generation, delivering high quality stable clones of your choice. Guaranteed, gram level GS expression cell line delivered in just 4 months.

Process Development

GenScript offers upstream and downstream bioprocess services that include cell culture condition improvement, optimization of feeding strategies, scale-up to bioreactor, purification process development, protein modification process development and analytical assay development.

GLP-Compliant Bioprocess

Use our GLP-compliant bioprocess services for your recombinant protein and therapeutic antibody needs for in vivo studies. Smoothly integrate results for manufacturing and regulatory application. Learn More

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Oligonucleotide Synthesis

Starting at $0.39 per sample

DNA Oligo synthesis from $0.39
RNA Oligo synthesis from $5

DNA Oligo synthesis from $0.39
RNA Oligo synthesis from $5

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Open Reading Frame Cloning

Price on request
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Patch Clamp Recording

Price on request
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Peptide Synthesis

Price on request

GenScript provides high-quality peptides with a 95% peptide synthesis success rate, well above the industry standard of 75%. We are committed to Total Quality Management (TQM) to ensure our customers' complete satisfaction. TQM includes MS and HPLC analyses performed after the completion of synthesis, purification, and QC (quality... Show more »

GenScript provides high-quality peptides with a 95% peptide synthesis success rate, well above the industry standard of 75%. We are committed to Total Quality Management (TQM) to ensure our customers' complete satisfaction. TQM includes MS and HPLC analyses performed after the completion of synthesis, purification, and QC (quality control) steps. These analyses are followed by independent QA (quality assurance) procedures, which double guarantees the highest quality possible for every delivered peptide.

Peptide Synthesis Capacity and Capability

Our custom peptides are synthesized in a 20,000 square foot state-of-the-art facility with peptide synthesizers, HPLCs, and mass spectrometers capable of producing over 6000 peptides per month. Other features of our capacity and capability include:

  • Capacity: 10,000 peptides / month.
  • Flexible quantities: From mg to kg.
  • Flexible purities: Crude, desalt, and from 70% to 98% purity.
  • Synthesis technologies: Combination of solid phase and liquid phase synthesis, and microwave and ligation technologies via our Flexpeptide™ technology platform.
  • Modifications: Include phosphorylation, methylation, acetylation, amidation, stable isotope labeling, and many more.
  • Quality control: MS and HPLC analyses after each synthesis step, plus additional QA procedures for every peptide.
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In vivo PK/PD Studies

Price on request
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Plasmid DNA Preparation

Price on request

GenScript plasmid DNA preparation services cover individual constructs for research labs as well as large scale manufacturing for biotech and pharmaceutical companies. GenScript’s high quality plasmids will help you achieve highly efficient cell transfection, DNA vaccination, antibody production, and other preclinical studies.

GenScript plasmid DNA preparation services cover individual constructs for research labs as well as large scale manufacturing for biotech and pharmaceutical companies. GenScript’s high quality plasmids will help you achieve highly efficient cell transfection, DNA vaccination, antibody production, and other preclinical studies.

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Polyclonal Antibody Production

Price on request
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Predictive Toxicology

Price on request
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RNAi Screening

Price on request
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Recombinant Protein Expression

Price on request

B. subtilis, P. pastoris

B. subtilis, P. pastoris

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Site-Directed Mutagenesis

Starting at $149.00 per sample

Site-directed mutagenesis is central to molecular biology, facilitating research in a variety of fields, including studies of gene regulatory elements, DNA-protein interaction, protein structure/function, enzyme active sites, and novel proteins. GenScript's site-directed mutagenesis services, powered by sophisticated gene... Show more »

Site-directed mutagenesis is central to molecular biology, facilitating research in a variety of fields, including studies of gene regulatory elements, DNA-protein interaction, protein structure/function, enzyme active sites, and novel proteins. GenScript's site-directed mutagenesis services, powered by sophisticated gene synthesis technology and high performance GS polymerase, include point mutations, deletions, and insertions. They can be customized to fit any scientific applications.

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Genetically Engineered Mice

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Targeting vector construction is a prerequisite for the generation of genetically engineered animals. GenScript's advanced molecular biology platform has provided thousands of targeting vectors to customers worldwide. These targeting vectors have been successfully used in traditional and conditional knock-out, knock-in, and many other genetic modification projects.

Targeting vector construction is a prerequisite for the generation of genetically engineered animals. GenScript's advanced molecular biology platform has provided thousands of targeting vectors to customers worldwide. These targeting vectors have been successfully used in traditional and conditional knock-out, knock-in, and many other genetic modification projects.

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Monoclonal Antibody (mAb) Production

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Protein Services

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Mammalian Cell Culture

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Microbiology

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Drug Discovery

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Computational Modeling

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ADME/DMPK Studies

Drug Metabolism and Pharmacokinetics
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Genetic Engineering

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Cell and Tissue Culture

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Specialized Cell-Based Assays

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Chemistry and Materials

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Biospecimen Management and Storage

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Pharmacology & Toxicology

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Drug Discovery & Development

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Molecular Cloning

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Synthetic Chemistry

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Cells and Tissues

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Transgenic Mouse Services

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RNA Services

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Virology Services

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Cell Electrophysiology

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Therapeutic Monoclonal Antibody (mAb) Development

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Transfection

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Cytotoxicity Assays

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Biochemistry & Molecular Biology

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Transgenic Animal Model Development

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Lead Identification and Validation

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Cell-Based Assays

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Nucleic Acid Services

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Mutagenesis

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Cell Death Assays

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Protein Production

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Toxicology

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Biology

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Antibody Services

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Hit Identification

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Virus Production

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Plasmids and Vectors

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Electrophysiology

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Electrophysiology Services

Electrophysiology Services

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Biomolecular Interaction Analysis

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Biomolecular Interaction Analysis Services

Biomolecular Interaction Analysis Services

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Protein Arrays

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Protein Arrays Services

Protein Arrays Services

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Proteomics

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Proteomics Services

Proteomics Services

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Omics

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Omics Services

Omics Services

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Oligonucleotides

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Oligonucleotides Services

Oligonucleotides Services

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In vivo ADME/DMPK Studies

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In vivo ADME/DMPK Studies Services

In vivo ADME/DMPK Studies Services

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Pharmacology

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Pharmacology Services

Pharmacology Services

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  • Positive review for Peptide Synthesis:

    July 2017

    "Good communication and timeline respected"

GenScript USA Inc has not received any endorsements.