GenoSplice Technology

GenoSplice provides bioinformatics services. With a unique expertise, we develop and market services with high added value for genomic data analysis. GenoSplice technical developments are focused on development of innovative useful and powerful solutions to take full advantage of new technologies such as high-throughput sequencing and microarrays. GenoSplice services based on long term and confident relationship mainly concern the data analysis: gene expression, alternative splicing, microRNA, fusion transcripts, epigenetics, SNP, CNV, translocation and proteomics.

Our main goals are:

• Allowing to manage a huge quantity of data from your laptop with our dedicated platform;
• Turning raw complex data into easy-to-interpret biological information.

Many optimal and dedicated solutions have been conducted with prestigious and challenging private and public players in North America, Europe and Asia. GenoSplice has worked in various areas such as fundamental research, pharma industry, cosmetology, and environment. Since 2005, more than hundred publications with co-authorship or citing our technologies are available in PubMed.

Recent Publications

• Control of neuronal synapse specification by a highly dedicated alternative splicing program. Traunmüller L, Gomez AM, Nguyen TM, Scheiffele P., Science, 2016 May
• Discordant Growth of Monozygotic Twins Starts at the Blastocyst Stage: A Case Study. Noli L, Capalbo A, Ogilvie C, Khalaf Y, Ilic D., Stem Cell Reports, 2015 Nov
• Molecular analyses of juvenile granulosa cell tumors bearing AKT1 mutations provide insights into tumor biology and therapeutic leads. Auguste A, Bessière L, Todeschini AL, Caburet S, Sarnacki S, Prat J, D’Angelo E, de la Grange P, Ariste O, Lemoine F, Legois B, Sultan C, Zider A, Galmiche L, Kalfa N, Veitia RA, Hum Mol Genet. 2015 Sep
• SF3B1 mutations are associated with alternative splicing in uveal melanoma. Furney SJ, Pedersen M, Gentien D, Dumont AG, Rapinat A, Desjardins L, Turajlic S, Piperno-Neumann S, de la Grange P, Roman-Roman S, Stern MH, Marais R., Cancer Discov. 2013 Jul
• RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation. Bechara EG, Sebestyén E, Bernardis I, Eyras E, Valcárcel J, Mol Cell. 2013 Dec