The University of Minnesota Genomics Center (UMGC) provides genomics research services committed to advancing genomics in Minnesota. The UMGC maintains and acquires state-of-the-art instrumentation and offers an array of services including sequencing, expression, genotyping, nucleic acid extraction and related support. We strive to keep pace with the ever-broadening world of “omics” technologies (genomics, epigenomics, metabolomics), and to expand our role at the University and the wider biotech community.
What we do
Provide genomics research services for UMN investigators and external companies. Although the primary goal of the UMGC is to provide a diverse portfolio of research services to UMN investigators, we also have a mandate to translate discoveries in genomics to the founding of knowledge-based companies in the State of Minnesota.
Assess and acquire emerging technologies to drive the expansion of biomedical and agricultural research. Genomics technologies evolve at a rapid pace. The efficient and well-planned evaluation and acquisition of new instrumentation is paramount in maintaining a competitive advantage for UMN researchers and external clients.
Advise clients on choosing appropriate technology for research goals.
The Infinium assay is a high-throughpout assay intended for high density SNP genotyping and CNV analysis over the entire genome. Illumina Infinium technology can also be customized using iSelect for large numbers of custom SNPs and developed to fit any experimental design.
Custom Genotyping Arrays
Human Genotyping Arrays
Plant and Animal Genotyping Arrays
Truseq Custom Amplicon Genotyping
Agena (formerly Sequenom) iPLEX Service Options
Provides flexible, high quality, high throughput SNP Genotyping to the University of Minnesota research community.
Low plex--(1-40 SNPs)--Agena iPlex: An excellent choice for researchers seeking to genotype/allelotype a limited # of well characterized SNPs in many samples.
Using the same platform we offer Oncogene Mutation Detection and Profiling, and also solutions for agricultural genomics including copy number variation (CNV), mutation detection using MALDI TOF MS.
iPLEX Gold is a leading technology for SNP Genotyping. The iPLEX Gold assay has been used in hundreds of publications to routinely design assays at multiplexing levels up to 40-plex, offering a high level of flexibility and a low cost per genotype. Use iPLEX Gold for:
-Validation of GWAS studies
-Routine genetic testing with SNP panels of interest
ADME PGx Genotyping:
Translational medicine researchers, as well as pharmaceutical and biotechnology companies require genotyping tools to screen for genetic changes that may influence drug response.The iPLEX® ADME PGx panel can help scientists quickly and reliably screen samples for genotypes relevant to drug metabolism by simultaneously analyzing 192 key biomarkers across 36 ADMET-related genes. The iPLEX ADME PGx panel consists of 200 assays in 8 wells requiring 10 ng of input DNA per well from fresh or frozen whole blood or cells. After the sample is run, mutations are detected, quantified, and a haplotype report is created using the TYPER software. With the MassARRAY system, you can choose the entire iPLEX ADME PGx panel, or custom-design specific assay panels of interest.
Somatic Mutation Profiling:
We offer Sequenom’s somatic mutation panels to accelerate basic cancer and translational research efforts.
(there are 3 panels) comprise a large collection of assays for over 50 oncogenes and tumor suppressors previously identified through GWAS, arrays, and sequencing. The entire collection of OncoCarta research mutation panels can be used for:
-Identification of candidate markers for drug discovery and development
-Basic cancer research studies
-Alternatively, a more focused selection of mutations can be designed into a custom panel. Visit Assay Explorer to search through the panels for your mutations of interest, or request a custom design.
is used for rapid screening of melanoma samples using targeted discovery panel of >70 somatic mutations in 20 genes.
In both of the above applications you can
-Use tumor samples from fresh, frozen, or formalin fixed, paraffin embedded tissues (FFPE) and/or cell lines.
-Analyze multiple loci with as little as 160 ng DNA per sample.
-Detect and quantify mutation frequencies from ≥ 10%.
Genomics Center has not received any reviews.
Genomics Center has not received any endorsements.