Genome International Corporation (GIC) is a research-driven firm providing innovative bioinformatics products and custom research solutions for corporate, government, and academic laboratories in biomedical and plant sciences. Our scientists and engineers are passionate about delivering high quality yet cost effective products and services by innovating advances in bioinformatics and information technologies to optimize the management, analysis and mining of high-throughput molecular biology data.
Certifications: - 8(a) Small Disadvantaged Business (SDB) - Economically Disadvantaged Woman-Owned Small Business (EDWOSB) - CIO-SP3 – GIC holds the NIH Chief Information Officer – Solutions and Partners (CIO-SP3) GWAC as part of a JV
Standard shipping requests: DNA samples can be shipped overnight at room temperature in a sterile container. RNA samples degrade easily and they are usually shipped frozen on dry ice. Other standard shipping procedures apply.
RoBuST: an integrated genomics resource for the root and bulb crop families Apiaceae and Alliaceae. A Bhasi, D Senalik, PW Simon, B Kumar, V Manikandan, P Philip, and P Senapathy, BMC Plant Biology (2010), 10:161, http://www.biomedcentral.com/1471-2229/10/161
Targeted Genome-wide Enrichment of Functional Regions. Senapathy P, Bhasi A, Mattox J, Dhandapany PS, Sadayappan S., PLoS ONE (2010) Jun 16;5(6);e11138
ExDom: an integrated database for comparative analysis of the exon-intron structures of protein domains in eukaryotes. Ashwini Bhasi et al. Nucleic Acids Research (2009) Database Issue 37:D703-D711
AspAlt: A tool for inter-database, inter-genomic and customized comparative analysis of alternative transcription and alternative splicing in eukaryotes. Ashwini Bhasi et al. Genomics (2009) 94(1):48-54
De novo genome assembly is typically carried out when a reference genome sequence of a particular organism is unavailable. The process involves putting together overlapping pieces of DNA obtained from sequencing of unknown template DNA (from an organism). It is a computationally intensive process and requires a number of parameter adjustments based on the nature of the organism. GIC's services include draft genome assembly plus detailed genome annotation, which can be visualized in a powerful genome browser environment.
Micro RNAs are a class of small non-coding RNAs of length 18-22bp. Recent discoveries about the functions and roles of miRNAs have sparked great interest in the study of a new level of gene regulation involved in development and disease.
Chromatin immunoprecipitation (ChIP) followed by sequencing is a powerful method to determine the locations of DNA binding sites for a protein (transcription factor) of interest. Determining protein-DNA interactions involved in gene regulation is essential to fully understand biological processes and diseases.
Analyze genome-wide DNA methylation patterns by immunoprecipitation of methylated cytosines or based on bisulfite conversion of methylated cytosines to uracil.
A quick and effective strategy to identify disease-causing genes for rare Mendelian disorders. The strategy is also being applied to profile all variants in complex diseases such as Cancer, Diabetes and AMD.
Comprehensive method to understand gene expression and regulation in development and disease. Time-series data, data from genetic variants, and data from microarray platforms, are all supported.
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