Genemarkers
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Kalamazoo, Michigan, US
Genemarkers is contract research organization that specializes in genomics. Genemarkers provides gene expression and genotyping services for pharmaceutical, biotechnology and personal care companies. Studies are used to support all phases of molecular research, from biomarker discovery to the development of a molecular diagnostic test.
Under the auspices of its CLIA lab, the company provides PGX (pharmacogenomics) and genetic testing - enabling physicians with information to guide personalized treatments. PGX testing is used to identify which drugs will work best for an individual patient, reducing trial and error and adverse drug responses.
The company is a certified woman owned company (WBENC) and has been recognized as one of the Top 50 Companies to Watch in 2013. Dr. Anna Langerveld, PhD, President and CEO was a semi-finalist in the Edward Lowe Entrepeneur of the Year Award in 2013.
Genemarkers has developed a microRNA gene expression panel. The microRNA Panel is a Taqman qPCR-based test that screens 105 microRNA targets that regulate skin functions, including cell proliferation and turnover, inflammation and the response to stress. Genemarkers microRNA Panel can be run using in vitro skin equivalents or clinical samples. Turn-around-time is approximately 2 to 3 weeks. Deliverables include a publication quality report.
Genemarkers has developed a Melanogenesis gene expression panel. The Melanogenesis Panel is a Taqman qPCR-based test that contains 52 target genes that regulate melanin production including growth factors, receptors and molecules involved in packaging and transfer of melanosomes. Genemarkers Melanogenesis Panel is run using primary normal human melanocytes. Turn-around-time is approximately 2 to 3 weeks. Deliverables include a publication quality report.
Genemarkers has developed a Standard Skin Biology gene expression panel. The Standard Skin Panel is a Taqman qPCR-based test that contains 107 target genes that regulate basic skin biology functions, including epidermal barrier formation and integrity, inflammation, cell proliferation, anti-oxidant/response to stress. Genemarkers Standard Skin Panel can be run using in vitro skin equivalents or clinical samples. Turn-around-time is approximately 2 to 3 weeks. Deliverables include a publication quality report.
Gene expression is measured with quantitative real time PCR (qPCR) using validated Taqman assays – the gold standard in gene expression. These assays are run in the latest Quantstudio 12K Flex instrument in an OpenArray format. This format allows for high throughput, cost-effective analysis.
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