At Frontage the foundation of our business is built on our ability to collaborate with a wide breadth of clients in the pharmaceutical and biopharmaceutical industry. We have relationships with the top pharma companies as well as small start-up organizations. We support generic, innovator and consumer health companies with their IND, NDA, ANDA, and 505(b)(2) submissions and provide flexible solutions that are customized to each client’s needs.
We are committed to providing rigorous scientific expertise to ensure the highest quality and compliance. We successfully assist clients to advance hundreds of molecules through development to commercial launch in global markets.
Our wide breath of laboratory and clinical services offer our clients solutions over the entire spectrum of the product development pipeline ranging from discovery through late-stage development.
• Our laboratory services offerings include DMPK, Bioanalytical, and CMC. With over 16 years of experience, we have over 400 scientists in 3 facilities located in the USA and China. Our senior scientists average 10 – 15 years in complex drug development and many come from leading Pharmaceutical companies.
• Our clinical services portfolio includes Phase I-IIa and biometrics services. We have 160 beds in our Secaucus NJ clinic and 18 sites with over 300 beds in China. Our Biometrics services supports Early to late stage programs.
We offer residual analyses, syntheses of metabolite standards and GLP in vivo/in vitro studies with radiolabeled compounds.
• Animal, plant and soil metabolism
• In vitro/In vivo studies
• GLP mass balance studies
• Bioanalytical studies
• Chemistry support
• Syntheses of metabolite standards
• Physical/chemical profiling
• Product certification
• Formulation stability
The highly trained and experienced scientific team provides broad and in-depth expertise/advice to clients on appropriate study designs, execution of studies, and interpretation of the data. We offer extensive drug metabolism and pharmacokinetic capabilities for new chemical entities and compounds in development.
Radiolabeled and non-labeled compounds
Single and multiple dose studies
Multiple species (mice, rats, dogs, monkeys, minipigs)
Oral, dermal, IP, SQ, IV
Special surgical techniques
Bile duct/hepatic portal vein
Frontage Laboratories is the first CRO to validate multiple SimoaTM (Single Molecule Array) instruments in a GLP regulated environment. SimoaTM technology provides a novel and ultra-sensitive method for detecting and quantifying biomolecules in biological specimens at femtomolar concentrations. This very low-level detection is difficult or impossible to measure on other instrument platforms. The sensitivity of Quanterix Simoa analyzer makes it the instrument of choice for ultra-sensitive analysis of biomarkers.
Frontage’s experienced bioanalytical scientists support a full suite of services using state-of-the-art instrumentation
Our expertise includes development of more than 1400 proprietary and non-proprietary methods and the yearly throughput of more than 500,000 samples analyzed in regulated, GLP and GCP settings
Agricultural Testing Services
• Field soil dissipation
• Magnitude of the residue
• Crop field trials & storage stability
• Livestock feeding studies (cattle, poultry)
• Analytical methods development
• Independent Laboratory Validations (ILV)
Animal Absorption, Distribution, Metabolism and Excretion
Degradation (hydrolysis, photodegradation)
Aerobic and anaerobic metabolism (soil, aquatic)
Mobility (absorption/desorption, soil column leaching)
Fish bioaccumulation (metabolite identification)
Confined accumulation (rotational crop)
Field rotational crop
You will find Frontage is outstanding at performing pivotal biosciences research. We offer pivotal toxicology studies for safety toxicity and toxicity evaluation of candidate compounds. Our toxicological studies are conducted on a variety of animal models, ranging from IND-enabling to smaller tox studies, and provide a basis for identifying hazards and conducting safety assessments that support IND filing and support use in humans. Our IND-enabling toxicology is performed by experienced scientists who can recommend appropriate study parameters and protocol elements, enabling the collection of a robust and comprehensive data package for IND submission. We offer comprehensive expertise to execute your IND study needs with services optimized to meet the most aggressive execution timelines.
Business Operations and Logistics Support Services
"Frontage Laboratories is a great scientific and technical partner for all drug discovery and development activities. Their staff is highly professional and responsive to customer needs and timelines. The work is schedule quickly, the data generated is of high quality as are the reports."
Frontage Laboratories has not received any endorsements.