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Discovery Life Sciences

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Powell, Ohio, US

About Discovery Life Sciences

Founded: 2005 Type: Privately Held Size: 51-200 employees

Conversant Bio, Folio Bio, Discovery Life Sciences and Phylogeny announced today that they have merged under the name Discovery Life Sciences™ (Discovery) to create a global market leader in biospecimen analysis and procurement for the pharmaceutical, biotechnology, and diagnostics industries.

The new... Show more »

Conversant Bio, Folio Bio, Discovery Life Sciences and Phylogeny announced today that they have merged under the name Discovery Life Sciences™ (Discovery) to create a global market leader in biospecimen analysis and procurement for the pharmaceutical, biotechnology, and diagnostics industries.

The new company will leverage deep scientific expertise and consultative services, combined with the largest repository of more than 10 million research-quality biospecimens—all available and processed for analysis—to accelerate the discovery, research, and development of novel biomarkers, drug candidates, and diagnostics.

Water Street Healthcare Partners, a strategic investor focused exclusively on the healthcare industry, facilitated the merger and invested in the company.

Glenn Bilawsky, a longtime executive in the pharmaceutical and contract research industries, is Discovery's CEO. “We’ve created an organization to provide researchers with significant added value through our consultative 'SmartSourcing™' model, which creates intelligent partnerships to overcome research problems and accelerate progress, saving both time and money,” he said. “We retain the world’s most diverse base of high-quality biospecimens and the global logistical systems to acquire, process, biostore, and ship them most efficiently, with adherence to all local and international laws.”

With a particular emphasis in oncology; cardiology; neurology; and infectious, inflammatory, and autoimmune diseases, the newly combined company’s catalog includes normal, suspect, and disease-state specimens comprising rare diseases and racially and ethnically diverse exemplars. Discovery obtains these biosamples through its Discovery Partners™, a global, integrated network of more than 165 clinical sources, in 25 countries on six continents. Due to these clinical partners, Discovery is unmatched in its ability to recruit the most diverse patient populations and obtain the highest quality of ethically obtained clinical research specimens.

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Our Services (13)


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Histology and Pathology Services

Price on request

Discovery accesses a deep reservoir of specimens, facilities, technologies, and expertise to equip our clients with large-scale, custom services in pathology, histology, and tissue characterizations.

• The largest biorepository of FFPE samples offers depth and breadth of disease areas.
• Sophisticated laboratories are... Show more »

Discovery accesses a deep reservoir of specimens, facilities, technologies, and expertise to equip our clients with large-scale, custom services in pathology, histology, and tissue characterizations.

• The largest biorepository of FFPE samples offers depth and breadth of disease areas.
• Sophisticated laboratories are designed to fully support both preclinical and clinical studies.
• The latest technologies including high-resolution imaging to enhance the utility of deliverables.
• A staff of US board-certified pathologists to deliver quality assessments, interpretations, and confirmations.
• Experienced histology team to assemble tissue microarrays (TMA) for high-throughput screenings.
• A team of scientists proficient in custom-characterization design to identify biomarkers of interest.

SERVICE
Discovery is a full-service partner, equipped to be an extension of your lab. We leverage our expertise, facilities, and technology to support and accelerate your research. Imagine the benefits of sourcing and characterizing tissue samples from a single vendor:

• Reduced backlogs on internal laboratories and personnel
• Biospecimens and lab services accessed from a single vendor
• A dedicated point of contact across projects
• Simplified logistics and contracting
• Characterized samples relevant to your criteria
• High-throughput screening slides (TMA) that allow rapid future characterizations

Service Listing:
Pathology:
• Interpretation of stains
• Quality assessments of samples
• Diagnosis and confirmations

Histology:
• Sectioning and curls
• Fixation and embedding
• IHC, ISH, and other stains
• Staining optimizations
• Aperio Scanning Imaging

Characterization:
• TMA with IHC or ISH
• MTBs with IHC or ISH
• Whole Mounts with IHC or ISH
• Targeted Genomic Analysis
• Data reporting and management
• IHC optimization

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Aperio Leica BOND-III Leica BOND RX Flow cytometry PCR IHC FISH Biomarker discovery H&E staining Special staining PBMC Purification DTC purification tissue section Show 13 more tags Show less

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Flow Cytometry

Price on request

Discovery accesses a deep reservoir of specimens, facilities, technologies, and expertise to equip our researcher clients with large-scale, custom services in flow cytometry. Our scientists are accomplished in designing and executing flow cytometric analyses and provide custom consultations to optimize project results. Our team... Show more »

Discovery accesses a deep reservoir of specimens, facilities, technologies, and expertise to equip our researcher clients with large-scale, custom services in flow cytometry. Our scientists are accomplished in designing and executing flow cytometric analyses and provide custom consultations to optimize project results. Our team also can aide in panel design, such as the custom validation of fluorophores and antibody clones for your assays. Our scientist analyze and report data outputs. Sophisticated technologies are used in our flow cytometry laboratory; these have high-throughput and automation capabilities to handle large-scale projects. Our primary cell processing facility incorporates a dedicated, separate flow cytometry laboratory.

SERVICE
Discovery is a full-service partner, equipped to be an extension of your lab. We leverage our expertise, facilities, and technology to support and accelerate your research. Data from flow cytometry services are provided as both a simplified summary analysis and raw data files. Imagine the benefits of sourcing and characterizing cell-based samples from a single vendor:

SCIENCE
Discovery accesses a deep reservoir of specimens, facilities, technologies, and expertise to equip our researcher clients with large-scale, custom services in flow cytometry. Our scientists are accomplished in designing and executing flow cytometric analyses and provide custom consultations to optimize project results. Our team also can aide in panel design, such as the custom validation of fluorophores and antibody clones for your assays. Our scientist analyze and report data outputs. Sophisticated technologies are used in our flow cytometry laboratory; these have high-throughput and automation capabilities to handle large-scale projects. Our primary cell processing facility incorporates a dedicated, separate flow cytometry laboratory.

SERVICE
Discovery is a full-service partner, equipped to be an extension of your lab. We leverage our expertise, facilities, and technology to support and accelerate your research. Data from flow cytometry services are provided as both a simplified summary analysis and raw data files. Imagine the benefits of sourcing and characterizing cell-based samples from a single vendor:

• Reduced backlogs on internal laboratories and personnel
• Biospecimens and lab services accessed from a single vendor
• A dedicated point of contact across projects
• Simplified logistics and contracting
• Reduced flow cytometer maintenance time and costs
• Characterized samples relevant to your criteria

Service Examples:
• Cell population analysis
• DNA content analysis
• Cell proliferation status
• Intracellular protein analysis
• 12-plex cytokine analysis
• Activation and exhaustion status of immune cells
• Marker expression of cell populations
• HLA
• PD1
• PD-L1
• CTLA-4

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Miltenyi MacsQuant Immunology Oncology Hematology Immuno-Oncology Healthy PD-L1 HLA PD1 Show 9 more tags Show less

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Omics

Price on request

Discovery accesses a deep reservoir of specimens, facilities, technologies, and expertise to equip our researcher clients with large-scale, custom services in oncogene testing, sequencing, and ancillary genomic services.

• Services developed and overseen by leading experts in the development and application of genomic and
... Show more »

Discovery accesses a deep reservoir of specimens, facilities, technologies, and expertise to equip our researcher clients with large-scale, custom services in oncogene testing, sequencing, and ancillary genomic services.

• Services developed and overseen by leading experts in the development and application of genomic and
bioinformatic technologies and methods.
• Vast clinical network and biorepository to source biospecimens for large-scale genomic characterization projects.
• Sophisticated genomic laboratories designed specifically for high-throughput sequencing services to support
translational and clinical-based projects.
• Front-line genomic research tools including: RNAseq, CATCH-Seq, 10X Genomics' Chomium™ Platform, TruSight
Tumor 170™.
• Robust data management and project support, including delivery of raw sequencing data and bioinformatic
analysis by highly skilled scientists with leading genomic analysis tools.
• For more details about our genomic services, please begin a consultation with your business development
manager or submit the form below.

SERVICE
Discovery's genomic services identify relevant biomarkers in both cell and tissue samples, including blood, cell isolations, tissue dissociations, and FFPE. These services are designed to produce high-quality data. For example, our sequencing standards default to high-read depths unless lower read depths are specifically requested.

The benefits of sourcing and genomically characterizing biospecimens from a single vendor partner include:

• Reduced backlogs on internal laboratories and personnel
• Biospecimens and lab services accessed from a single vendor
• A dedicated point of contact across projects
• Simplified logistics and contracting
• Characterized samples relevant to your criteria
• The expertise of respected professionals in genomic services

Service Listing:
• Oncogene Panels:
• Microsatellite instability (MSI)
• Specific mutational analysis -
• EGFR, BRAF, KRAS, HPV, NRAS, etc.
• TruSight Tumor 170™

Sequencing:
• Whole exome sequencing (WES)
• Whole transcriptome analysis (RNAseq)
• HLA sequencing via Complete MHC
• Single-cell genomic analysis via 10x Genomics' Chromium™ platform

Ancillary Services:
• DNA isolation and purification
• RNA isolation and purification
• Data management
• Bioinformatic analysis

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Biomarker analysis mRNA-seq miRNA-seq Whole Exome Sequencing Whole Genome Sequencing DNA Microsatellite Analysis Mutation Detection Single cell 10x Genomics Chromium System Show 10 more tags Show less

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Human Primary Cells

Price on request

Discovery scientists have validated and standardized multiple primary immune cell isolations from healthy donors. Utilizing modern technologies and gentle selection protocols, flow cytometry attests that our standard cell isolations deliver high purity. We use flow cytometry to characterize donors for peripheral blood immune cell... Show more »

Discovery scientists have validated and standardized multiple primary immune cell isolations from healthy donors. Utilizing modern technologies and gentle selection protocols, flow cytometry attests that our standard cell isolations deliver high purity. We use flow cytometry to characterize donors for peripheral blood immune cell subsets and genetic sequencing for HLA status. We store and transport samples using high-quality storage media that is free of animal protein to avoid unnecessary activation of cells. Our scientists are continually investigating further cellular isolations to add to our standard offerings. We have cultivated a deep expertise in applying cellular isolations to custom projects. Our team is available for consultations to optimize the results of studies involving our tissue dissociations.

Through our proprietary healthy donor network and collection clinic, Discovery can support large projects that require:

• Recallable donors for longitudinal collections
• HLA-A typing status for donors
• Faster than average accruals
• Sourcing from a large patient cohort

Our primary immune cell isolations are derived from human apheresis collections and delivered as cryopreserved vials of single-cell suspensions. Each specimen has guaranteed cell counts following our Thawing Viable Cell Products protocol. Our large healthy donor network allows for large-scale prospective collections, while also supporting our robust bank of inventory samples.

Customized laboratory services are available and include custom: isolations, aliquoting, processing of leukopaks, flow cytometry characterization, targeted genomic analysis, and more.

Service Listing:
• Isolations from viable cell products (PBMCS, DTCs, BMMCs, etc.)
• Customized processing of leukopaks
• Culturing for cell expansion, activation, and/or differentiation
• Flow cytometry characterization
• Targeted genomic characterization

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Human Healthy Primary Cells cd8 CD4

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Human Blood Collection Service

Price on request

Discovery scientists have deep experience adapting protocols and processes to support custom blood projects. Equipped with ISO-certified laboratory facilities and sophisticated technology, our scientists develop and validate custom protocols for research clients with specific project requirements.

We also customize laboratory... Show more »

Discovery scientists have deep experience adapting protocols and processes to support custom blood projects. Equipped with ISO-certified laboratory facilities and sophisticated technology, our scientists develop and validate custom protocols for research clients with specific project requirements.

We also customize laboratory processes and protocols, including cell isolations, genomic sequencing, HLA testing, and patient characterization.

SERVICE
Discovery offers the full spectrum of blood-based biospecimens, from whole blood to double-spun plasma, and diseased patients to healthy donors. Discovery Partners®, our network of more than 165 clinical sources in 25 countries on six continents, enables large-scale, prospective collections, while also supporting our robust bank of inventory samples. Each diseased specimen is provided with the base clinical data from the patient case, along with a redacted pathology report. Our scientific team has the knowledge and technical capacity to meet custom requirements and offer laboratory services for blood-based projects.

Disease Areas
Oncology · Autoimmune Diseases · Normal Control Samples · Hematology · Cardiovascular · Gastroenterology · Infectious Diseases · Liver Disease

Biospecimen Formats:
Fresh, Whole Blood · Peripheral Blood Mononuclear Cells (PBMCs) · Plasma · Double-Spun Plasma · Serum · Buffy Coat · Cord Blood · Bone Marrow · Bone Marrow Mononuclear Cells (BMMCs)

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Immunology Oncology Hematology CNS/Neurology Cardiovascular Infectious Disease Immuno-Oncology Inflammation Healthy Show 9 more tags Show less

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Human Biobanking

Price on request

Discovery has created one of the world’s largest in-house commercially available collections of formalin fixed paraffin embedded tissues.

Specimens from Discovery’s FFPE Biorepository are available, either as slides or blocks, with custom stains and other histology services. All in-house cases come from only US-based clinical... Show more »

Discovery has created one of the world’s largest in-house commercially available collections of formalin fixed paraffin embedded tissues.

Specimens from Discovery’s FFPE Biorepository are available, either as slides or blocks, with custom stains and other histology services. All in-house cases come from only US-based clinical settings, ensuring the highest ethical and quality standards. All tissue bank samples include an anonymized dataset with demographic information and a full pathology report. Collaboration with cancer registries and contributing hospitals maximize the availability of extended medical information such as hormone receptor status, chemotherapy, family history, etc. Many cases include outcome and follow-up information covering periods up to 25 years. The Discovery Tissue Biobank supplies researchers with a convenient and cost-effective way to select relevant cases from major types of cancer.

Discovery offers the full spectrum of blood-based biospecimens, from whole blood to double-spun plasma, and diseased patients to healthy donors. Discovery Partners®, our network of more than 165 clinical sources in 25 countries on six continents, enables large-scale, prospective collections, while also supporting our robust bank of inventory samples. Each diseased specimen is provided with the base clinical data from the patient case, along with a redacted pathology report. Our scientific team has the knowledge and technical capacity to meet custom requirements and offer laboratory services for blood-based projects.

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Human Immunology Oncology Rare Disease CNS/Neurology Gastroenterology Infectious Disease Metabolism and Endocrinology Alzheimers Disease Ulcerative colitis Crohn's disease Parkinson's disease (PD) Whole blood FFPE tissue serum plasma Frozen Tissue Cerebrospinal fluid body fluid tissue section EDTA Whole Blood Lithium Heparin Whole Blood Lithium Heparin Plasma Drug Discovery Show 24 more tags Show less

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Human Biospecimens

Price on request

Open access Biorepository with >500k specimens available for immediate delivery consisting of Clinical samples, Patient specimens and Human Biofluids such as but not limited to: Whole Blood, Serum, Plasma, PBMC's, CSF, Amniotic Fluid, Urine, Stool, PAP Smears, Cervical and Genital Swabs, Throat, Nasal & Pharyngeal Swabs, Sputum,... Show more »

Open access Biorepository with >500k specimens available for immediate delivery consisting of Clinical samples, Patient specimens and Human Biofluids such as but not limited to: Whole Blood, Serum, Plasma, PBMC's, CSF, Amniotic Fluid, Urine, Stool, PAP Smears, Cervical and Genital Swabs, Throat, Nasal & Pharyngeal Swabs, Sputum, FFPE Tissue & Frozen Tissue. Expertise in facilitating global prospective collections under IRB/EC approval.
Cohorts include but not limited to: Infectious Diseases, Cancer, Fetal-Maternal Health, Bacterial, Viral and Parasitic Diseases, Cardiac Diseases, Autoimmune, Endocrine and Metabolic Disorders, Chemistry and Immunology, FLU/Respiratory Viruses, Normal Control Patients.
Comprehensive BioSample Management for Clinical Research Programs.
Customized Patient BioSample Kit Design and Development.
Patient BioSample Kit Assembly and Site Distribution.
Infectious Substance Class 6.2 Patient Biosample Packaging & Shipping Logistics.
DiscoveryTrak Customized Collection Kits.
BioRepository Storage and Services.

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Bone Marrow Mononuclear Cells

Price on request

Cryopreserved samples and fresh collections are available. Send us a request for more information about the data provided with these samples.

Cryopreserved samples and fresh collections are available. Send us a request for more information about the data provided with these samples.

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Fresh Human Tissue

Price on request
Request a quote for more information about this service.
Whole blood Urine serum plasma Fresh Tissue Fresh Tumors Fresh Frozen Show 7 more tags Show less

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Tissue Microarrays

Price on request

Custom Tissue Microarray Manufacturing

Tissue arrays, or tissue microarrays (TMAs), may contain hundreds of samples on a single slide. TMAs enable researchers to make the best use of tissue specimens while increasing throughput and improving accuracy, reproducibility, and statistical data. The human tissue used in our arrays... Show more »

Custom Tissue Microarray Manufacturing

Tissue arrays, or tissue microarrays (TMAs), may contain hundreds of samples on a single slide. TMAs enable researchers to make the best use of tissue specimens while increasing throughput and improving accuracy, reproducibility, and statistical data. The human tissue used in our arrays has recently been procured under the most ethical guidelines. Discovery’s tissue standardization process provides consistent results from slide to slide. All TMAs have a prolonged shelf life and support a wide range of scientific applications. A board-certified pathologist verifies each tissue used in the arrays. All TMAs include a slide layout and tissue pathology information including age, sex, diagnosis and the location of each sample positioned on the slide. Ideal for using in your next immunohistochemistry, FISH or miRNA ISH study, Folio’s human tissue microarrays are the perfect cost-effective research tool, allowing high throughput analysis with statistical precision cutting bench time in half. In addition to the human tissue slides listed below, custom microarrays can be constructed according to your specific research requirements.

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Clinical Trial Management

Price on request

Through our Discovery Partners™ program of >100 contracted clinical sites globally, we facilitate clinical trial management for the ethical acquisition of human bio-fluids and annotated clinical data under IRB/EC approval and informed patient consent from normal, suspect and disease state subjects. We provide services such as... Show more »

Through our Discovery Partners™ program of >100 contracted clinical sites globally, we facilitate clinical trial management for the ethical acquisition of human bio-fluids and annotated clinical data under IRB/EC approval and informed patient consent from normal, suspect and disease state subjects. We provide services such as clinical site selection and validation, study document development, IRB/EC submissions through study close out, clinical study training, monitoring/auditing, custom collection kit development, close out, clinical sample logistics and global transportation of clinical samples, data and more.

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CLIA Certification

Clinical Laboratory Improvement Amendements certification
Price on request
Request a quote for more information about this service.

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Bioanalytical Assay Validation

Price on request

ValidateNOW

Custom sample kits, reference panels and proficiency panels consisting of clinically characterized samples or diagnostic reference specimens which can contain analytically predetermined specimens across the dynamic or functional range of an assay that can be used for research and development, training laboratory personnel, learning new procedures, techniques and test methods.

ValidateNOW

Custom sample kits, reference panels and proficiency panels consisting of clinically characterized samples or diagnostic reference specimens which can contain analytically predetermined specimens across the dynamic or functional range of an assay that can be used for research and development, training laboratory personnel, learning new procedures, techniques and test methods.

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Chief Commercial Officer
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