Protein purification and bioconjugation services are our business. We are noted for expertise bioconjugation and conjugate vaccines. We also provide CRM197 for conjugation.
Here is what we offer:
Recombinant protein production for laboratory and preclinical projects. Starting from the amino acid sequence, we will optimize the sequence, clone into E. coli, optimize expression and deliver purified protein, either His-tagged or unmodified.
We can assist at any stage of your protein production and help with scale up or purification issues. Our experts have extensive experience with bacterial systems in the expression of difficult proteins, including improving the solubility of expressed protein and inclusion body refolding.
We provide analytical SEC HPLC and small scale preparative SEC. Detection using UV, RI and multi-angle light scattering (MALS)
Fluorescent labeling and biotinylation of antibodies. We do not perform antibody drug conjugation or radiolabeling. mg to gram scale.
We provide peptide, oligosaccharide and polysaccharide conjugation to proteins, including the vaccine carrier protein CRM197.
Biotinylation of up to 5 mg of antibody.
Turn-around time: 3 days
Protein A and Protein G antibody purification from mg to multi-gram scale
Absolute molecular weight determination for proteins, polysaccharides and conjugates using a Wyatt Helios8 light scattering SEC HPLC MALS
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