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Farcast Biosciences

2 Orders Completed
Woburn, Massachusetts, US

About Farcast Biosciences

Founded: 2009 Type: Privately Held Size: 51-200 employees

Farcast Biosciences is a diagnostic company focused on facilitating the identification of therapies for cancer patients before they begin treatment and is also optimized to test drug candidates prior to clinical trials. The Farcast platform is ideal for analyzing target engagement, understanding... Show more »

Farcast Biosciences is a diagnostic company focused on facilitating the identification of therapies for cancer patients before they begin treatment and is also optimized to test drug candidates prior to clinical trials. The Farcast platform is ideal for analyzing target engagement, understanding mechanism of action and identifying novel biomarkers. The platform recapitulates the human tumor microenvironment by culturing fresh unmodified human tumor fragments in a proprietary ex vivo histoculture system that includes patient matched immune cells and plasma.

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Our Services (6)


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Tumor Profiling

Price on request

Farcast's screening platform starts with a robust network of partnerships with hospitals to source fresh human tumors and matched blood. The fresh tumor fragments are cultured in a proprietary system that includes patient matched blood cells and plasma, indication matched tumor matrix proteins. This system is optimal for... Show more »

Farcast's screening platform starts with a robust network of partnerships with hospitals to source fresh human tumors and matched blood. The fresh tumor fragments are cultured in a proprietary system that includes patient matched blood cells and plasma, indication matched tumor matrix proteins. This system is optimal for testing single and combination therapies for target engagement and efficacy as well as mechanism of action. 

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Immuno-oncology Assays

Price on request

Farcast's proprietary ex vivo platform cultures fresh unmodified human tumor fragments with patient matched immune cells and plasma to recapitulate the human tumor microenvironment. The preservation of the human TME and immune compartment are essential to accurately evaluate therapies that engage the immune system, making... Show more »

Farcast's proprietary ex vivo platform cultures fresh unmodified human tumor fragments with patient matched immune cells and plasma to recapitulate the human tumor microenvironment. The preservation of the human TME and immune compartment are essential to accurately evaluate therapies that engage the immune system, making Farcast the optimal choice for gaining insights into immuno-oncology therapies. The dynamic nature of our human platform enables tracking of critical biological elements such as infiltration of CD8+ cytotoxic T-cells or natural killer cells into the tumor.

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Oncology Immuno-Oncology

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Biology

Price on request

Farcast is a truly human, phenotypic platform that allows direct, simultaneous interrogation of patient tumors with multiple therapies to answer questions on efficacy and mechanism of action.Multiple therapeutic options can be weighed simultaneously and with a high degree of accuracy, avoiding toxicity, and saving precious time... Show more »

Farcast is a truly human, phenotypic platform that allows direct, simultaneous interrogation of patient tumors with multiple therapies to answer questions on efficacy and mechanism of action.Multiple therapeutic options can be weighed simultaneously and with a high degree of accuracy, avoiding toxicity, and saving precious time and resources that would otherwise be consumed in the administration of sequential treatments. 

We source tissues and complete the culture protocols so the only requirements are client drug candidates. The deliverables include FFPE tissue microarray (TMA) blocks and three 96-well plates containing culture supernatant  representing the T24, T48 and T72 hour culture timepoints. TMA maps and pathology scoring for tumor content and necrosis in each fragment with  proliferation and apoptosis indices in the tumor cells per fragment will be included. 

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Immuno-Oncology Oncology

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Cells and Tissues

Price on request

We source tissues and complete the culture protocols so the only requirements are client drug candidates. The deliverables include FFPE tissue microarray (TMA) blocks and three 96-well plates containing culture supernatant  representing the T24, T48 and T72 hour culture timepoints. TMA maps and pathology scoring for tumor... Show more »

We source tissues and complete the culture protocols so the only requirements are client drug candidates. The deliverables include FFPE tissue microarray (TMA) blocks and three 96-well plates containing culture supernatant  representing the T24, T48 and T72 hour culture timepoints. TMA maps and pathology scoring for tumor content and necrosis in each fragment with  proliferation and apoptosis indices in the tumor cells per fragment will be included. 

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Ex Vivo Models and Assays

Price on request

Farcast's proprietary ex vivo platform cultures fresh unmodified human tumor fragments with patient matched immune cells and plasma to recapitulate the human tumor microenvironment. The preservation of the human TME and immune compartment are essential to accurately evaluate therapies that engage the immune system, making... Show more »

Farcast's proprietary ex vivo platform cultures fresh unmodified human tumor fragments with patient matched immune cells and plasma to recapitulate the human tumor microenvironment. The preservation of the human TME and immune compartment are essential to accurately evaluate therapies that engage the immune system, making Farcast the optimal choice for gaining insights into immuno-oncology therapies. 

The workflow starts with a robust network of partnerships with hospitals to source fresh human tumors and matched blood. The fresh tumor fragments are cultured in a proprietary system that includes patient matched blood cells and plasma, indication matched tumor matrix proteins. This system is optimal for testing single and combination therapies for target engagement and efficacy as well as mechanism of action. 

Show less

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Cytokine Analysis

Price on request

The deliverables include FFPE tissue microarray (TMA) blocks and three 96-well plates containing culture supernatant  representing the T24, T48 and T72 hour culture timepoints. The culture supernatants can be assayed for cytokine levels using standard assays. 

The deliverables include FFPE tissue microarray (TMA) blocks and three 96-well plates containing culture supernatant  representing the T24, T48 and T72 hour culture timepoints. The culture supernatants can be assayed for cytokine levels using standard assays. 

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Emilie Clement

Business Development Manager
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Lucy Coassin

Regional Sales Director West Coast
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Anjli Venkateswaran

Director, Strategic Marketing

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