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Expesicor

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Kalispell, Montana, US

About Expesicor

Founded: 2016 Type: Privately Held Size: 1-10 employees

We offer an array of preclinical GLP-compliant services. Our core competence is neuroscience R&D. Our primary techniques are used for in vitro and in vivo efficacy and toxicology. For example, induced hippocampal neurodegeneration (neuroprotection), rodent models, transgenic models, video-EEG... Show more »

We offer an array of preclinical GLP-compliant services. Our core competence is neuroscience R&D. Our primary techniques are used for in vitro and in vivo efficacy and toxicology. For example, induced hippocampal neurodegeneration (neuroprotection), rodent models, transgenic models, video-EEG monitoring, behavioral assays, microbiome sequencing/analysis, and histology. Our focus disease areas include neurological disorders, e.g. Alzheimer's disease (AD), epilepsy, traumatic brain injury (TBI), mild cognitive impairment, and chronic traumatic encephalopathy (CTE).

Services
Hippocampal neurodegeneration (neuroprotection), rodent models, transgenic models, video-EEG monitoring, behavioral assays, microbiome sequencing/analysis, preclinical study design, best practice consulting for data and IP security, experimental design around patentability assessments, and histology

Our team has experience navigating and strategizing intellectual property filings. We are a patent holding company (drug and animal model patents) with vast experience designing experiments around legal patentability assessments.

Our team has experience applying to ~25 U.S state/federal, European, and foundation grants. Several grants received by our researchers.

Selected publications
- Kienzler-Norwood F, et al. "A novel animal model of acquired human temporal lobe epilepsy based on the simultaneous administration of kainic acid and lorazepam." Epilepsia. 2017.
- Meyer M, et al. "Removing entorhinal cortex input to the dentate gyrus does not impede low frequency oscillations, an EEG-biomarker of hippocampal epileptogenesis." Nature Scientific Reports. 2016
- Will J, et al. "Enhanced sequential reaction time task performance in a rat model of mesial temporal lobe epilepsy with classic hippocampal sclerosis." Behavioral Brain Research. 2013.
- Norwood BA, et al. "Electrical stimulation-induced seizures in rats: a dose-response study on resultant neurodegeneration." Epilepsia. 2011.
- Norwood BA, et al. “Classic hippocampal sclerosis and hippocampal-onset epilepsy produced by a single "cryptic" episode of focal hippocampal excitation in awake rats.“ Journal of Comparative Neurology. 2010.

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Diversity Certificates

Small business

Our Services (31)


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Neurodegeneration Animal Models

Price on request

Various in vivo rodent models of neurodegeneration, based on chemical (e.g. kainic acid) and electrical (e.g. perforant pathway) stimulation.

Various in vivo rodent models of neurodegeneration, based on chemical (e.g. kainic acid) and electrical (e.g. perforant pathway) stimulation.

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CNS/Neurology Aging Neurodegenerative diseases Alzheimers Disease Traumatic brain injury (TBI) Seizures Pulmonary Thromboendarterectomy (PTE) Parkinson's disease (PD) Mild cognitive impairment Dementia Post traumatic epilepsy Show 11 more tags Show less

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Preclinical Histology

Price on request

Various histological methods including Nissl staining and immunocytochemistry/immunohistochemistry, and analyses such as stereology (i.e. neuron counting). Also stains for neurodegeneration, such as Fluorojade.

Various histological methods including Nissl staining and immunocytochemistry/immunohistochemistry, and analyses such as stereology (i.e. neuron counting). Also stains for neurodegeneration, such as Fluorojade.

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Aging Neurodegenerative diseases Alzheimers Disease Epilepsy Traumatic brain injury (TBI) Seizures Pulmonary Thromboendarterectomy (PTE) Mild cognitive impairment Dementia Post traumatic epilepsy Show 10 more tags Show less

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Digital Pathology Image Analysis

Price on request
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Preclinical Study Design

Price on request

We have substantial experience designing dozens of preclinical experiments.

We have substantial experience designing dozens of preclinical experiments.

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Epilepsy & Seizure Animal Models

Price on request

Includes evoked and spontaneous seizure models. With and without video-EEG monitoring.

Includes evoked and spontaneous seizure models. With and without video-EEG monitoring.

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Mouse Rat CNS/Neurology Epilepsy Seizures Pulmonary Thromboendarterectomy (PTE) Post traumatic epilepsy Show 7 more tags Show less

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Preclinical Population Studies

Price on request
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In vivo Drug Efficacy Testing

Price on request

Efficacy studies on neuroprotection, anti-seizure, and anticonvulsant effects. Relevant to various neurodegenerative disorders and brain injury.

Efficacy studies on neuroprotection, anti-seizure, and anticonvulsant effects. Relevant to various neurodegenerative disorders and brain injury.

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Histology and Pathology Services

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Animal Electroencephalography (EEG)

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Video-EEG monitoring (mice and rats) utilizing telemeters (for free movement) and infrared cameras

Video-EEG monitoring (mice and rats) utilizing telemeters (for free movement) and infrared cameras

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Telemeters Neurodegenerative diseases Alzheimers Disease Epilepsy Traumatic brain injury (TBI) Seizures Pulmonary Thromboendarterectomy (PTE) Parkinson's disease (PD) Mild cognitive impairment Dementia Post traumatic epilepsy Video-EEG monitoring EEG Show 13 more tags Show less

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Cybersecurity Consulting

Price on request

Consulting on data security best practices for VPNs, zero-knowledge cloud storage platforms, intellectual property data storage best practices, private 1:1 communication methods, enterprise-grade security communication platforms.

Consulting on data security best practices for VPNs, zero-knowledge cloud storage platforms, intellectual property data storage best practices, private 1:1 communication methods, enterprise-grade security communication platforms.

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Microbiome Sequencing

Price on request

Methods including 16s/18s RNA, DNA sequencing, and Bioinformatics to determine alpha- and beta-diversity of populations within a sample.

Methods including 16s/18s RNA, DNA sequencing, and Bioinformatics to determine alpha- and beta-diversity of populations within a sample.

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Bioinformatics DNA sequencing

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Microbiome Studies

Price on request

Services to analyze and quantify microbial populations within samples, e.g. stool or cecal.

Services to analyze and quantify microbial populations within samples, e.g. stool or cecal.

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DNA sequencing Stool

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Animal Models of Disease

Price on request

Rodent models of neurological disorders/injuries.

Rodent models of neurological disorders/injuries.

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CNS/Neurology Alzheimers Disease Epilepsy Traumatic brain injury (TBI) Seizures Pulmonary Thromboendarterectomy (PTE) Parkinson's disease (PD) Post traumatic epilepsy Video-EEG monitoring EEG Show 10 more tags Show less

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Animal Behavior Studies

Price on request

We offer an array of behavioral assays that includes, but is not limited to: Barnes maze, Morris water maze, radial arm (water) maze, rotorod, novel object recognition, object-place recognition task, open-field test.

We offer an array of behavioral assays that includes, but is not limited to: Barnes maze, Morris water maze, radial arm (water) maze, rotorod, novel object recognition, object-place recognition task, open-field test.

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Neurodegenerative diseases Epilepsy Traumatic brain injury (TBI) Post traumatic epilepsy Barnes maze Morris water maze Radial arm (water) maze Rotorod Novel object recognition Object-place recognition task Open-field test Show 11 more tags Show less

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Animal Learning, Memory, and Behavior Tests

Price on request

Barnes maze, Morris water maze, radial arm (water) maze, rotorod, novel object recognition, object-place recognition task, open-field test

Barnes maze, Morris water maze, radial arm (water) maze, rotorod, novel object recognition, object-place recognition task, open-field test

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CNS/Neurology Neurodegenerative diseases Alzheimers Disease Epilepsy Traumatic brain injury (TBI) Pulmonary Thromboendarterectomy (PTE) Parkinson's disease (PD) Post traumatic epilepsy Open field Barnes maze Object recognition test Morris water maze Radial arm (water) maze Rotorod Novel object recognition Object-place recognition task Open-field test Show 17 more tags Show less

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Next Generation Sequencing (NGS)

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DNA Sequencing

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Animal Model in vivo Analyses

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CNS/Neurology Neurodegenerative diseases Alzheimers Disease Epilepsy Traumatic brain injury (TBI) Seizures Pulmonary Thromboendarterectomy (PTE) Parkinson's disease (PD) Post traumatic epilepsy histology Video-EEG monitoring EEG Show 12 more tags Show less

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Animal Cognition & Behavior Tests

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Open field Barnes maze Object recognition test Morris water maze Radial arm (water) maze Rotorod Novel object recognition Object-place recognition task Open-field test Show 9 more tags Show less

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CNS/Neurology Animal Models

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CNS/Neurology Neurodegenerative diseases Alzheimers Disease Epilepsy Traumatic brain injury (TBI) Seizures Pulmonary Thromboendarterectomy (PTE) Parkinson's disease (PD) Post traumatic epilepsy Show 9 more tags Show less

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Nucleic Acid Services

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Microbiology

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Animal Models and Studies

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Aging Neurodegenerative diseases Alzheimers Disease Traumatic brain injury (TBI) Pulmonary Thromboendarterectomy (PTE) Parkinson's disease (PD) Mild cognitive impairment Dementia Post traumatic epilepsy Show 9 more tags Show less

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Clinical and Anatomic Pathology

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Clinical and Anatomic Pathology Services

Clinical and Anatomic Pathology Services

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Clinical Laboratory Services

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Clinical Laboratory Services

Clinical Laboratory Services

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Clinical Research

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Clinical Research Services

Clinical Research Services

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Image Analysis

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Image Analysis Services

Image Analysis Services

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Data Services

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Data Analysis and Management Services. Consulting on data security best practices for VPNs, zero-knowledge cloud storage platforms, private 1:1 communication methods, enterprise-grade security communication platforms.

Data Analysis and Management Services. Consulting on data security best practices for VPNs, zero-knowledge cloud storage platforms, private 1:1 communication methods, enterprise-grade security communication platforms.

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Project Management

Price on request

Project Management & Consulting Services

Project Management & Consulting Services

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Histopathological Examination

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Assay Development

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Braxton Norwood

Director of Neuroscience

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