Hyo18pqsuz9xkc7ik4a0 expes

Expesicor

No Reviews Yet
No Completed Orders
Kalispell, Montana, US

About Expesicor

Founded: 2016 Type: Privately Held Size: 1-10 employees

We offer an array of preclinical GLP-compliant services. Our core competence is neuroscience R&D with a focus in epilepsy and epilepsy-like disease modeling and treatment. Our goal is to provide the infrastructure necessary for Investigational New Drug (IND) development for the prevention and cure of neurologic disease. Our primary techniques are used for in vitro and in vivo drug development, addressing efficacy and toxicology. Techniques and models include: induced hippocampal neurodegeneration and subsequent neuroprotection against, rodent models, transgenic models, video-EEG monitoring, behavioral assays, microbiome sequencing/analysis, and histology. Disease areas include neurological disorders, e.g. Alzheimer's disease (AD), epilepsy, traumatic brain injury (TBI), mild cognitive impairment, and chronic traumatic encephalopathy (CTE).

Services
Hippocampal neurodegeneration (neuroprotection), rodent models, transgenic models, video-EEG monitoring, behavioral assays, microbiome sequencing/analysis, histology, preclinical study design, best practice consulting for data and IP security, and experimental design around patentability assessments.
Our team has experience navigating and strategizing intellectual property filings. We are a patent holding company (drug and animal model patents) with vast experience designing experiments around legal patentability assessments.
Our team has experience applying to ~25 U.S state/federal, European, and foundation grants. Several grants have been received by our researchers.
**Selected publications** - Kienzler-Norwood F, et al. "A novel animal model of acquired human temporal lobe epilepsy based on the simultaneous administration of kainic acid and lorazepam." *Epilepsia*. 2017. - Meyer M, et al. "Removing entorhinal cortex input to the dentate gyrus does not impede low frequency oscillations, an EEG-biomarker of hippocampal epileptogenesis." *Nature Scientific Reports*. 2016 - Will J, et al. "Enhanced sequential reaction time task performance in a rat model of mesial temporal lobe epilepsy with classic hippocampal sclerosis." *Behavioral Brain Research*. 2013. - Norwood BA, et al. "Electrical stimulation-induced seizures in rats: a dose-response study on resultant neurodegeneration." *Epilepsia*. 2011. - Norwood BA, et al. “Classic hippocampal sclerosis and hippocampal-onset epilepsy produced by a single "cryptic" episode of focal hippocampal excitation in awake rats.“ *Journal of Comparative Neurology*. 2010.

Diversity Certificates

Small business

Our Services (28)


ic

Neurodegeneration Animal Models

Price on request

Various in vivo rodent models of neurodegeneration, based on chemical (e.g. kainic acid) and electrical (e.g. perforant pathway) stimulation.

Neurodegenerative diseases CNS/Neurology Alzheimers Disease Parkinson's disease (PD) Post traumatic epilepsy Dementia Mild cognitive impairment Aging Seizures Pulmonary Thromboendarterectomy (PTE) Traumatic brain injury (TBI) Show 11 more tags Show less

ic

Preclinical Histology

Price on request

Various histological methods including Nissl staining and immunocytochemistry/immunohistochemistry, and analyses such as stereology (i.e. neuron counting). Also stains for neurodegeneration, such as Fluorojade.

Epilepsy Traumatic brain injury (TBI) Neurodegenerative diseases Post traumatic epilepsy Pulmonary Thromboendarterectomy (PTE) Alzheimers Disease Seizures Dementia Mild cognitive impairment Aging Show 10 more tags Show less

ic

Digital Pathology Image Analysis

Price on request
Request a quote for more information about this service.

ic

Preclinical Study Design

Price on request

We have substantial experience designing dozens of preclinical experiments.


ic

Epilepsy & Seizure Animal Models

Price on request

Includes evoked and spontaneous seizure models. With and without video-EEG monitoring.

Epilepsy Seizures Pulmonary Thromboendarterectomy (PTE) CNS/Neurology Post traumatic epilepsy Mouse Rat Show 7 more tags Show less

ic

Preclinical Population Studies

Price on request
Request a quote for more information about this service.

ic

In vivo Drug Efficacy Testing

Price on request

Efficacy studies on neuroprotection, anti-seizure, and anticonvulsant effects. Relevant to various neurodegenerative disorders and brain injury.


ic

Histology and Pathology Services

Price on request
Request a quote for more information about this service.

ic

Animal Electroencephalography (EEG)

Price on request

Video-EEG monitoring (mice and rats) utilizing telemeters (for free movement) and infrared cameras

Epilepsy Pulmonary Thromboendarterectomy (PTE) Traumatic brain injury (TBI) Neurodegenerative diseases Alzheimers Disease Parkinson's disease (PD) Seizures Post traumatic epilepsy Dementia Mild cognitive impairment EEG Telemeters Video-EEG monitoring Show 13 more tags Show less

ic

Cybersecurity Consulting

Price on request

Consulting on data security best practices for VPNs, zero-knowledge cloud storage platforms, intellectual property data storage best practices, private 1:1 communication methods, enterprise-grade security communication platforms.


ic

Microbiome Studies

Price on request

Services to analyze and quantify microbial populations within samples, e.g. stool or cecal.

DNA sequencing Stool

ic

Animal Models of Disease

Price on request

Rodent models of neurological disorders/injuries.

Traumatic brain injury (TBI) Pulmonary Thromboendarterectomy (PTE) Epilepsy Post traumatic epilepsy Alzheimers Disease Parkinson's disease (PD) Seizures Video-EEG monitoring EEG CNS/Neurology Show 10 more tags Show less

ic

Animal Behavior Studies

Price on request

We offer an array of behavioral assays that includes, but is not limited to: Barnes maze, Morris water maze, radial arm (water) maze, rotorod, novel object recognition, object-place recognition task, open-field test.

Neurodegenerative diseases Traumatic brain injury (TBI) Epilepsy Post traumatic epilepsy Barnes maze Morris water maze Radial arm (water) maze Rotorod Novel object recognition Object-place recognition task Open-field test Show 11 more tags Show less

ic

Animal Learning, Memory, and Behavior Tests

Price on request

Barnes maze, Morris water maze, radial arm (water) maze, rotorod, novel object recognition, object-place recognition task, open-field test

CNS/Neurology Neurodegenerative diseases Epilepsy Post traumatic epilepsy Pulmonary Thromboendarterectomy (PTE) Traumatic brain injury (TBI) Alzheimers Disease Parkinson's disease (PD) Barnes maze Morris water maze Radial arm (water) maze Rotorod Novel object recognition Object-place recognition task Open-field test Open field Object recognition test Show 17 more tags Show less

ic

Animal Model in vivo Analyses

Price on request
Request a quote for more information about this service.
Epilepsy Alzheimers Disease Neurodegenerative diseases Pulmonary Thromboendarterectomy (PTE) Traumatic brain injury (TBI) Parkinson's disease (PD) Seizures CNS/Neurology Post traumatic epilepsy EEG Video-EEG monitoring histology Show 12 more tags Show less

ic

Animal Cognition & Behavior Tests

Price on request
Request a quote for more information about this service.
Barnes maze Morris water maze Radial arm (water) maze Rotorod Novel object recognition Object-place recognition task Open-field test Open field Object recognition test Show 9 more tags Show less

ic

CNS/Neurology Animal Models

Price on request
Request a quote for more information about this service.
Epilepsy Post traumatic epilepsy Pulmonary Thromboendarterectomy (PTE) Traumatic brain injury (TBI) Alzheimers Disease Parkinson's disease (PD) Seizures Neurodegenerative diseases CNS/Neurology Show 9 more tags Show less

ic

Microbiology

Price on request
Request a quote for more information about this service.

ic

Animal Models and Studies

Price on request
Request a quote for more information about this service.
Alzheimers Disease Parkinson's disease (PD) Neurodegenerative diseases Traumatic brain injury (TBI) Post traumatic epilepsy Pulmonary Thromboendarterectomy (PTE) Dementia Mild cognitive impairment Aging Show 9 more tags Show less

ic

Clinical and Anatomic Pathology

Price on request

Clinical and Anatomic Pathology Services


ic

Clinical Laboratory Services

Price on request

Clinical Laboratory Services


ic

Clinical Research

Price on request

Clinical Research Services


ic

Image Analysis

Price on request

Image Analysis Services


ic

Data Services

Price on request

Data Analysis and Management Services. Consulting on data security best practices for VPNs, zero-knowledge cloud storage platforms, private 1:1 communication methods, enterprise-grade security communication platforms.


ic

Project Management

Price on request

Project Management & Consulting Services


ic

Assay Development

Price on request
Request a quote for more information about this service.

ic

Histopathological Examination

Price on request
Request a quote for more information about this service.

ic

Imaging Training

Price on request
Request a quote for more information about this service.

Not finding what you're looking for?

Get info on this provider's capabilities without requesting a quote.

Expesicor has not received any reviews.

Expesicor has not received any endorsements.