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Experimentica Ltd.

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About Experimentica Ltd.

Founded: 2013 Type: Privately Held Size: 11-50 employees

Experimentica Ltd. is a contract research organization (CRO) dedicated to developing and offering preclinical ocular models and services to clients in the pharmaceutical, biotech and academic sectors.

In Vitro Ocular Models

  • Primary retinal pigment epithelium cells
  • hiPSC derived retinal pigment... Show more ยป

Experimentica Ltd. is a contract research organization (CRO) dedicated to developing and offering preclinical ocular models and services to clients in the pharmaceutical, biotech and academic sectors.

In Vitro Ocular Models

  • Primary retinal pigment epithelium cells
  • hiPSC derived retinal pigment epithelium cells (Phenocell, France)
  • Primary neurons
  • Primary optic nerve head astrocytes
  • Primary lacrimal acinar cells
  • Human corneal epithelium cells (HCE-T, Riken, Japan)
  • Human photoreceptor cell line (retinoblastoma, WERI-Rb-1, Riken, Japan)
  • Primary bovine retinal endothelium cells

In Vivo Ocular Models:

  • Glaucoma
  • Optic nerve damage
  • Ischemic optic neuropathy
  • Diabetic retinopathy
  • Age-related macular degeneration
  • Dry-eye disease
  • Retinopathy of prematurity
  • Retinal detachment

Ex Vivo Ocular Models:

  • Ex vivo retinal degeneration assay (adult retinal explant)
  • Corneal permeation assay (rabbit ex vivo cornea)

Publications (not limited to the following):

Wahlin, K. J. et al. Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. PloS one 8, e79140, doi:10.1371/journal.pone.0079140 (2013).

Kalesnykas, G. et al. Retinal ganglion cell morphology after optic nerve crush and experimental glaucoma. Investigative ophthalmology & visual science 53, 3847-3857, doi:10.1167/iovs.12-9712 (2012).

Oglesby, E. et al. Semi-automated, quantitative analysis of retinal ganglion cell morphology in mice selectively expressing yellow fluorescent protein. Experimental eye research 96, 107-115, doi:10.1016/j.exer.2011.12.013 (2012).

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Our Services (37)


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H&E Staining

Hematoxylin and eosin staining
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Immunohistochemistry (IHC)

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Patch Clamp Recording

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Stereology

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Quantitative and unbiased estimation of particles, cells, area, volume or length of region of interest.

Quantitative and unbiased estimation of particles, cells, area, volume or length of region of interest.

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Transmission Electron Microscopy (TEM)

Transmission Electron Microscopy services
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Tissue Preparation

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We offer paraffin embedding and sectioning, cryosectioning, vibratome sectioning, resin embedding and sectioning of CNS and PNS tissue (e.g. mouse, rat, rabbit, monkey).

We offer paraffin embedding and sectioning, cryosectioning, vibratome sectioning, resin embedding and sectioning of CNS and PNS tissue (e.g. mouse, rat, rabbit, monkey).

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Imaging & Spectroscopy

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Clinical Laboratory Services

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Clinical Research

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Biology

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Ophthalmology Animal Models

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Microscopy

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Animal Models of Disease

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Animal Models and Studies

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Biospecimens

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Tissue Processing

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Histological Staining

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Biochemistry & Molecular Biology

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Cells and Tissues

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In vitro Disease Models

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Electrophysiology

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Medical Imaging Services

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Electrophysiology Animal Models

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Custom Ophthalmology Animal Models

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Diabetic Retinopathy Animal Models

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CNS/Neurology Animal Models

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Macular Degeneration Animal Models

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Dry Eye Animal Models

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Glaucoma Animal Models

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In vitro Eye Models

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Cell Services

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Common Histochemical Stains

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Protein Expression Visualization

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Immunostaining

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Protein Services

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Electron Microscopy

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Clinical and Anatomic Pathology

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Justina Dragunaite

Manager, Business Office
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Jenni Hakkarainen

Chief Operating Officer
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Simon Kaja

Chief Scientific Officer

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