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Epistem Services Ltd

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Manchester, GB

About Epistem Services Ltd

Epistem is a specialist Contract Research Organisation and Pharmacogenomics company providing valuable support to drug discovery and development pipelines. Epistem’s experienced and skilled technical team are dedicated to working with you to provide custom protocols and a personalised service of the highest... Show more »

Epistem is a specialist Contract Research Organisation and Pharmacogenomics company providing valuable support to drug discovery and development pipelines. Epistem’s experienced and skilled technical team are dedicated to working with you to provide custom protocols and a personalised service of the highest standard.

Our contract research services include:-

• Oncology- Target validation, novel therapeutic agent efficacy in specialised tumour models and GCLP compliant biomarker studies

• GI Toxicity and Mucositis- Identification of the causes of changes to epithelial regulation; extensively characterised mucositis models

• Biodefence- GLP compliant evaluation of medical countermeasures for the acute and delayed effects of radiation exposure

• Inflammation-Extensively characterised in vivo IBD and CIA models and mechanistic pathways

• Skin-Living Skin Equivalents, organ cultures and full thickness skin graft models using defined donor skin types
• Wound Healing-In vitro assays and in vivo incisional and excisional models of wounding

• Analytical- Comprehensive range of endpoint analyses including IHC, imaging, FACS, multiplex and gene expression

Our Pharmacogenomic services include:-

• Gene Expression Analysis- provides global (microarray and NGS) and focused (qPCR) mRNA and miRNA gene expression profiling services.

• Plucked Hair Platform- Epistem provides a unique plucked hair biomarker platform to drug development companies targeting intracellular signalling pathways in oncology and other therapeutic areas.

• Laser capture Microdissection- Epistem offers Laser Capture Microdissection (LCM) services and subsequent gene expression and DNA genotype analysis. This technique is an ideal method for obtaining molecular analysis of specific cell populations.

• Assessing Limited Quantities of RNA- Epistem's proprietary amplification technique, RNA-Amp™, allows robust gene expression information to be derived from as little as a single cell input

• Gene Expression analysis- Epistem provides global (microarray and NGS) and focused (qPCR) mRNA and miRNA gene expression profiling services.

• DNA genotyping analysis- Epistem provides laboratory based services (microarray, NGS and qPCR) and Point of Care (Genedrive®) DNA genotyping tests.
• Liquid Biopsy analysis- Epistem Pharmacogenomics amplification technology is ideally suited for assessing fluid or tissue based samples that have limited quantities of RNA.

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Diversity Certificates

Small business

Our Services (89)


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DNA Microarrays

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Affymetrix GeneChip System 3000 Affymetrix GeneChip Workstation Agilent Microarray Affymetrix

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Colitis Animal Models

Price on request

Acute DSS-induced colitis
Acute TNBS-induced colitis
Adoptive T-cell transfer-induced colitis

Acute DSS-induced colitis
Acute TNBS-induced colitis
Adoptive T-cell transfer-induced colitis

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Mouse Rat

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Pharmacogenomics/Pharmacogenetics

Price on request

Epistem Pharmacogenomics are a GCLP accredited laboratory specialising in providing biomarker, target discovery and personalised medicine information to pharmaceutical companies from very limited quantities of RNA.
Our proprietary amplification technique RNA-Amp™ enables us to assess quantities of RNA down to a single cell input... Show more »

Epistem Pharmacogenomics are a GCLP accredited laboratory specialising in providing biomarker, target discovery and personalised medicine information to pharmaceutical companies from very limited quantities of RNA.
Our proprietary amplification technique RNA-Amp™ enables us to assess quantities of RNA down to a single cell input (10pg).
We are able to conduct pharmacogenomic assessments via:
• Microarrays
• NGS
• RT-qPCR
We have utilised this technology to provide pharmacogenomic information from:
• Single cells
• Plucked scalp hair (mouse, rat, dog, primate and human)
• Laser capture microdissected (LCM) tissue
• Fractionated blood cell populations (PBMC’s)
• Preclinical and clinical biopsies (in oncology and inflammatory diseases)
We are also able to provide extensive gene expression information from our proprietary database containing information that we have compiled from healthy normal volunteer samples and our own data from clinical and preclinical studies. Using this information, we can quickly recommend the appropriate tissue or sample to monitor drug response.

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Affymetrix GeneAtlas system Affymetrix GeneChip System 3000 Affymetrix GeneChip Workstation Fluidigm Biomark HD PCR thermal cycler Roche Lightcycler Human Mouse Rat Spotfire Immunology Oncology CNS/Neurology Fibrotic Disease Aging Cardiovascular Gastroenterology Nephrology and Urology Metabolism and Endocrinology Hepatology Inflammation Acute Myeloid Leukemia (AML) Acute Lymphocytic Leukemia (ALL) Alopecia Psoriasis Inflammatory Bowel Disease Breast cancer Alzheimers Disease Gastric Cancer Crohn's disease Bladder cancer qPCR Microarray qRT-PCR Blood Biopsy tissue Skin Drug Discovery Toxicology anti-aging biomarker Client-specified Beta arrestin Androgens carbohydrate kinase antibody affinity binding Cell proliferation and activity test Illumina Affymetrix Illumina NextSeq Large molecules/Biologics Small molecules Show 53 more tags Show less

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Analytical Chemistry Services

Price on request

Epistem provides a suite of analytical services which can be utilised as an integrated component of an in-house study package or as a stand-alone service.
Epistem proudly offers a GCLP accredited histology and immunohistochemistry service at a central facility in Manchester, UK. Additional facilities in Baltimore, MD provide... Show more »

Epistem provides a suite of analytical services which can be utilised as an integrated component of an in-house study package or as a stand-alone service.
Epistem proudly offers a GCLP accredited histology and immunohistochemistry service at a central facility in Manchester, UK. Additional facilities in Baltimore, MD provide local support for customers in the US. Delivered by a team of experienced histologists, reliable, quality controlled slides and data can be provided for any histological requirement. Associated image capture and morphological quantification can also be provided using the Aperio® ScanScope® digital slide scanner. High quality, publication-ready images with high throughput automated quantitative analysis can be produced with GLP compliant image archiving and analysis.
The first in the UK, Epistem’s facilities include the Bruker In Vivo Xtreme Imaging System. Combined with established expertise in imaging, this sophisticated, high resolution, multi-modal system is a powerful addition to Epistem’s in vivo preclinical models. Sensitive high throughput analysis of cell phenotypes by FACS, and proteins and cytokines by multiplex, is also provided in support of Epistem's models and assays and as a sample analysis service.
Epistem's gene expression service is a powerful tool providing highly sensitive, GCLP compliant sample analysis. This service specialises in providing robust and reliable gene expression information from very small amounts of starting material.
Epistem has been providing analytical support to drug discovery and development pipelines for over ten years. World-renowned expertise in epithelial stem cell biology, specifically in the gastrointestinal epithelium, skin and hair, forms the basis of Epistem's analytical services. This knowledge has been applied to provide exceptional support for Epistem's portfolio of pre-clinical models and a flexible, high quality solution for contract sample analysis.
Epistems Analytical services:
• Histology
• Immunohistochemistry
• Aperio® ScanScope®
• Bruker In Vivo Xtreme Imaging System
• FACS analysis
• Multiplex analysis
• Gene expression

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Liquid Biopsy

Price on request

Epistem Pharmacogenomics amplification technology is ideally suited for assessing RNA or DNA in fluid or tissue based samples that have limited starting materials including:
• Circulating Tumor Cells
• Circulating Free DNA
• Exosomes
• PBMC cell populations following separation by FACS analysis

Epistem Pharmacogenomics amplification technology is ideally suited for assessing RNA or DNA in fluid or tissue based samples that have limited starting materials including:
• Circulating Tumor Cells
• Circulating Free DNA
• Exosomes
• PBMC cell populations following separation by FACS analysis

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Gene Expression Analysis

Price on request

Epistem Pharmacogenomics provides global and focused GCLP accredited mRNA and miRNA gene expression profiling and data analysis services.
Microarray Analysis
Epistem Pharmacogenomics offers both Affymetrix and Agilent platforms enabling accurate expression analysis of the whole transcriptome. Sponsors can choose from... Show more »

Epistem Pharmacogenomics provides global and focused GCLP accredited mRNA and miRNA gene expression profiling and data analysis services.
Microarray Analysis
Epistem Pharmacogenomics offers both Affymetrix and Agilent platforms enabling accurate expression analysis of the whole transcriptome. Sponsors can choose from pre-designed or custom designed arrays. Whole genome array services are available for human, non-human primate, dog, rat and mouse species.
Next Generation Sequencing (NGS)
Epistem Pharmacogenomics offer RNA and DNA sequencing on Illumina NGS platforms.
qPCR Analysis
Epistem Pharmacogenomics offer focused Real-Time quantitative and qualitative PCR, with assays being designed and validated for industry standard performance based on a comparative Ct method.
Data Analysis
Epistem Pharmacogenomics undertake analysis of data by:
• Unbiased interrogation of genes differentially expressed between the relevant comparison groups and subsequent biological interpretation
• Focused analysis of the behaviour of genes or pathways of interest if appropriate.
Standard analysis will include comprehensive statistical analysis and ANOVAs based on group experimental factors. We conduct biological interpretation and pathway analysis using specialised software packages which enable the accurate interpretation of the biological meaning in genomics data. We also use the Broad Institute Connectivity map that links gene patterns associated with disease to corresponding patterns produced by drug candidates. We also specialise in deciphering gene expression information to obtain gene expression signatures relevant to specific compounds that can be used in clinical settings to monitor drug treatment.

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Fluidigm Biomark HD Illumina NextSeq 500 Roche Lightcycler Agilent Microarray Illumina Affymetrix Illumina NextSeq Fluidigm Show 8 more tags Show less

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Low Input/Single Cell RNA Sequencing

Price on request

Epistem Pharmacogenomics are a GCLP accredited laboratory specialising in providing biomarker, target discovery and personalised medicine information to pharmaceutical companies from very limited quantities of RNA.
Our proprietary amplification technique RNA-Amp™ enables us to assess quantities of RNA down to a single cell input... Show more »

Epistem Pharmacogenomics are a GCLP accredited laboratory specialising in providing biomarker, target discovery and personalised medicine information to pharmaceutical companies from very limited quantities of RNA.
Our proprietary amplification technique RNA-Amp™ enables us to assess quantities of RNA down to a single cell input (10pg).
We are able to conduct pharmacogenomic assessments via:
• Microarrays
• NGS
• RT-qPCR
We have utilised this technology to provide pharmacogenomic information from:
• Single cells
• Plucked scalp hair (mouse, rat, dog, primate and human)
• Laser capture microdissected (LCM) tissue
• Fractionated blood cell populations (PBMC’s)
• Preclinical and clinical biopsies (in oncology and inflammatory diseases)
We are also able to provide extensive gene expression information from our proprietary database containing information that we have compiled from healthy normal volunteer samples and our own data from clinical and preclinical studies. Using this information, we can quickly recommend the appropriate tissue or sample to monitor drug response.

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Plucked Hair Biomarker Analysis

Price on request

Epistem Pharmacogenomics provide a unique plucked hair biomarker platform which offers an attractive surrogate tissue for monitoring drug induced changes in gene expression profiles in oncology and inflammatory diseases.
Analysis of the bulb region of a single plucked hair provides a simple and minimally invasive technique to... Show more »

Epistem Pharmacogenomics provide a unique plucked hair biomarker platform which offers an attractive surrogate tissue for monitoring drug induced changes in gene expression profiles in oncology and inflammatory diseases.
Analysis of the bulb region of a single plucked hair provides a simple and minimally invasive technique to access epithelial tissue in:
• Preclinical settings - analysis of plucked hairs from rodents dogs and primates
• Clinical settings - analysis of single plucked hairs from humans
Using our extensive database containing gene expression profiling information from mouse, rat and human samples we can confirm if genes of interest are expressed in hair.
We have also developed an ex vivo model in which we can incubate hair plucked from healthy normal volunteers in culture, allowing us to establish drug related changes in gene expression which can guide selection of clinical biomarkers.
Hair is ideal surrogate tissue to monitor drug response and is easy to sample, with good patient compliance and few ethical issues. Hair expression profiling can assist drug development programs in the following areas:
• Pharmacodynamic Biomarkers - measuring the biological effect a drug has on a target
• Dose scheduling - by measuring the duration of drug effects over dose range and time
• Mechanism of action - bioinformatic analysis of drug response profile

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Wound Healing Animal Models

Price on request

Epistem draws on considerable expertise in the epithelial biology field to provide a range of wound healing models. This knowledge originated with the research of co-founders Prof. Chris Potten and Dr. Cath Booth. Epistem maintains strong links with the academic community, collaborating with Dr. Matthew Hardman at the University... Show more »

Epistem draws on considerable expertise in the epithelial biology field to provide a range of wound healing models. This knowledge originated with the research of co-founders Prof. Chris Potten and Dr. Cath Booth. Epistem maintains strong links with the academic community, collaborating with Dr. Matthew Hardman at the University of Manchester's Healing Foundation Centre. Dr. Hardman is a world-leading expert in the molecular and cellular aspects of pathological healing. This partnership enables Epistem to provide cutting-edge wound healing models and a broad and innovative service range.
Epistem's experienced team offers a range of models representing many of the complex aspects of wound healing including cell migration, proliferation, wound contraction and angiogenesis.

Epistem Wound Healing include:-
• In Vitro Wound Healing - cell proliferation, migration and wound contraction assays
• In Vivo Wound Healing - acute excisional and incisional wound healing models

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Inflammation Assays

Price on request

Rooted in academic excellence, Epistem's inflammation team has developed an extensive knowledge of the field and applied this experience to a portfolio of pre-clinical models. The team has been routinely performing in vitro and in vivo studies for the drug discovery industry for over 10 years. This comprehensive understanding of... Show more »

Rooted in academic excellence, Epistem's inflammation team has developed an extensive knowledge of the field and applied this experience to a portfolio of pre-clinical models. The team has been routinely performing in vitro and in vivo studies for the drug discovery industry for over 10 years. This comprehensive understanding of the models and assays offered enables Epistem to offer a consultative approach to study design; advice can be provided on selection of the most suitable model, particularly with reference to the performance of therapeutic agents. Epistem offers a range of in vivo disease models reflecting several key areas of autoimmune disease. Supported by a suite of mechanistic assays, these can provide a valuable and comprehensive data package.
Epistem continues to develop innovative and clinically relevant assays and models to support the drug discovery and development pipeline. Most recently a validated, in vitro model of psoriasis, addressing the need for a clinically relevant model within the industry, was added to the portfolio.

Epistem Inflammatory models:-

Disease models
• Inflammatory bowel disease
o Acute DSS model
o Acute TNBS Model
o T-cell transfer model
• Collagen-induced arthritis
Mechanistic Assays
• In vitro psoriasis model
• Leucocyte migration model
• Antigen presenting cell assay
• T-cell assays

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Human Mouse Rat Humanized Mouse Oncology Cardiovascular Gastroenterology Inflammation Acute Myeloid Leukemia (AML) Acute Lymphocytic Leukemia (ALL) Psoriasis Inflammatory Bowel Disease Ulcerative colitis Crohn's disease Large molecules/Biologics Small molecules Show 16 more tags Show less

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Acute Radiation Syndrome (ARS) Animal Models

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Epistem's expertise and history in radiation biology has been applied to the evaluation of potential mitigators of Acute Radiation Syndrome (ARS) to aid the development of medical countermeasures.
Epistem has worked with the USA's National Institute of Allergy and Infectious Disease (NIAID) funded Medical Countermeasures against... Show more »

Epistem's expertise and history in radiation biology has been applied to the evaluation of potential mitigators of Acute Radiation Syndrome (ARS) to aid the development of medical countermeasures.
Epistem has worked with the USA's National Institute of Allergy and Infectious Disease (NIAID) funded Medical Countermeasures against Radiological Threats (MCART) consortium. MCART was set up as a result of Project Bioshield which aims to protect the USA against weapons of mass destruction. Epistem has over 10 years of experience in the evaluation of ARS mitigators for NIAID and other US Government departments. Models are provided with variable levels of bone marrow shielding and types of medical management to mimic a variety of radiation exposures and clinical support measures.
Epistem also applies the knowledge and experience of these models to other therapeutic areas including the treatment and prevention of oncology therapy side effects and other causes of GI toxicity.
Epistems Biodefence models:-
• Acute Radiation Syndrome
• Gastrointestinal (GI-ARS)
• Haematopoietic (H-ARS)
• Delayed Effects of Acute Radiation Exposure (DEARE)

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Fluorescence Activated Cell Sorting (FACS)

Fluorescence Activated Cell Sorting
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BD FACSAria Cell Sorting System BD FacsCantoII/LSRII BD FACSort BD LSRFortessa BD LSRII

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Flow Cytometry

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BD FACSAria Cell Sorting System BD FacsCantoII/LSRII BD FACSort BD LSRFortessa BD LSRII BD FACSCalibur Show 6 more tags Show less

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Immunohistochemistry (IHC)

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Biomarker Analysis

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Flow cytometry Gene expression profiling

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Laser Capture Microdissection

Price on request

Epistem Pharmacogenomics are experts in isolating specific cell populations from tissue sections using Laser Capture Microdissection (LCM) and performing subsequent gene expression or DNA genotyping analysis.

The combination of LCM coupled with our ability to assess very limited quantities of RNA can be used for biomarker,... Show more »

Epistem Pharmacogenomics are experts in isolating specific cell populations from tissue sections using Laser Capture Microdissection (LCM) and performing subsequent gene expression or DNA genotyping analysis.

The combination of LCM coupled with our ability to assess very limited quantities of RNA can be used for biomarker, target discovery and safety assessment applications.

We conduct gene expression analysis on cells isolated from formalin-fixed, paraffin-embedded (FFPE) and fresh frozen samples. Our experts have developed highly sensitive proprietary techniques for the analysis of these samples and will provide guidance to customers when planning LCM studies to ensure optimal gene expression profiling.

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Gastrointestinal Toxicology

Price on request

Epistem's world renowned knowledge of gastrointestinal epithelial biology has been translated into a suite of pre-clinical models. The research of Epistem's co-founders, Prof. Chris Potten and Dr. Cath Booth, identified and characterised the location and behaviour of stem cells in the intestine, including the damaging effects of... Show more »

Epistem's world renowned knowledge of gastrointestinal epithelial biology has been translated into a suite of pre-clinical models. The research of Epistem's co-founders, Prof. Chris Potten and Dr. Cath Booth, identified and characterised the location and behaviour of stem cells in the intestine, including the damaging effects of chemotherapy and radiotherapy on the various cell populations.
These models can be used to support the development of novel therapeutic agents to:
• prevent or treat gastrointestinal or oral toxicity
• evaluate the risk of novel therapeutics causing toxicity and devise dosing strategies to minimise off-target responses
Mucositis is a specific form of GI toxicity associated with oncology therapy. Epistem's gold standard in vivo mucositis models can be used to assess potential mucositis therapies and determine whether a novel therapeutic agent causes mucositis. Epistem's mucositis team have been working in this area for over 20 years and were involved in the pre-clinical development of the only licensed prophylactic treatment for oral mucositis; Kepivance® (palifermin marketed by Biovitrum AB). This expertise in radiation biology has been recognised by the NIH where Epistem's models of radiation induced intestinal toxicity have been employed to evaluate potential radiation countermeasures.

Gi Toxicity and Mucositis models:-
Mucositis
• Oral mucositis
• Gastrointestinal mucositis
GI Toxicity Models
• 2D in vitro GI models
• 3D intestinal organoid model
• In vivo GI models

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Mouse Rat Rodents

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In vitro Oncology Models

Price on request

Epistem's oncology team has a wealth of experience taking therapeutic agents from early stage in vitro testing to clinical candidate nomination acquired in both academia and the pharmaceutical industry.
Epistem has extensive experience with standard of care chemotherapy agents and can provide radiotherapy models for the... Show more »

Epistem's oncology team has a wealth of experience taking therapeutic agents from early stage in vitro testing to clinical candidate nomination acquired in both academia and the pharmaceutical industry.
Epistem has extensive experience with standard of care chemotherapy agents and can provide radiotherapy models for the evaluation of tumour sensitisers. Facilities include a Bruker In Vivo Xtreme imaging system; a state of the art platform designed for complex pre-clinical investigations providing sensitive bioluminescent, fluorescent and radioisotopic imaging coupled with high resolution X-ray acquisition. Other imaging modalities including MRI, CT and PET are also available for monitoring tumour growth, development and metastasis.
Epistem continues to develop unique and innovative oncology models alongside academic and industry partners, including the application of luminescent and fluorescent optical imaging to orthotopic models
Epistem’s Oncology services
In Vitro Assays
• Target validation and cytotoxicity assays
• Cancer stem cell assay
• Angiogenesis
In Vivo models
• Angiogenesis
• Solid tumour xenograft models
• Orthotopic Models including Acute Myeloid and Lymphoblastic Leukemia
• Min+/- model of intestinal cancer
Plucked Hair platform
• Pre-clinical plucked hair assay
• Clinical plucked hair assay
Oncology therapy side effects
• Gastrointestinal toxicity, mucositis, alopecia, and bone marrow toxicity

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In vitro Skin Models

Price on request

Epistem's expertise and in-depth knowledge of epithelial cell biology has been applied to provide a comprehensive package of skin related models. Epistem's in-house skin services are provided by an experienced team, ensuring high quality reproducible data which can be used for claims and patent support. Analytical support is... Show more »

Epistem's expertise and in-depth knowledge of epithelial cell biology has been applied to provide a comprehensive package of skin related models. Epistem's in-house skin services are provided by an experienced team, ensuring high quality reproducible data which can be used for claims and patent support. Analytical support is provided by a fully GCLP accredited histology and immunohistochemistry service.
Epistem strives to provide clinically relevant ex vivo models, reducing the need for in vivo and human testing. Donor skin samples used for these models can be specified to ensure the model is representative of the required skin type.
Epistem won prestigious funding to develop a novel inflammatory human living skin equivalent model in collaboration with ScandiDerma. The grant, provided by the UK's Technology Strategy Board and Innovation Norway, recognises global leaders in innovation. Utilising Epistem's skin and inflammatory expertise, the collaboration aims to address the shortage of robust human skin models for testing inflammatory responses.
Read more...
Epistem's skin services can be used to investigate many aspects of skin biology including:
• UV-induced DNA damage
• Anti-ageing
• Cytotoxic potential of pharmaceutical components
• Stem cell response and skin regeneration potential
• Skin response to cancer therapy
• Hair growth and response to treatment
• Skin lightening and darkening
• Wound healing
Epsitems Skin Services:-
• Monolayer assays
• 3D skin models
Human living skin equivalent
Organ culture
• Human skin xenografts
• Hair growth model

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Protein Expression Visualization

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Immunostaining

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Safety Pharmacology

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Chemistry and Materials

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Protein Services

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Immunology Animal Models

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Bioanalysis

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Nucleic Acid Services

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Roche Lightcycler Regenerative Medicine Oncology Dermatology Infectious Disease Respiratory Immuno-Oncology Inflammation Inflammatory Bowel Disease PCR qPCR Gene expression profiling RNA-Seq mRNA-seq miRNA-seq DNA sequencing Gene expression arrays DNA microarrays Agilent Affymetrix Illumina NextSeq Fluidigm Show 22 more tags Show less

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Cells and Tissues

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Tissue Processing

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Viral Assays

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RNA Services

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Immunofluorescence

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Flow Cytometry Data Acquisition

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T Cell Activation and Proliferation Assays

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Oncology Animal Models

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Angiogenesis & Endothelial Cell Assays

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Gastrointestinal Disease Animal Models

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In vivo Drug Efficacy Testing

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Inflammation Animal Models

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Luminex Multiplex Assays

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DNA/RNA Analysis and Quality Control

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Animal Model in vivo Analyses

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RNA Quantification

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Assay Development

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In vitro Inflammation Models

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In vitro Wound Healing Assay

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Tissue Decalcification

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Imaging & Spectroscopy

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Computational Modeling

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Tissue Embedding

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Tissue Fixation

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In vivo Pharmacology Studies

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In vivo Pharmacology Studies Services

In vivo Pharmacology Studies Services

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Tissue Sectioning

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Natural Killer Cell Cytotoxicity Assay

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Animal Model Housing and Maintenance

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Primary Cell Culture

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Cell and Tissue Culture

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Cell and Tissue Culture Services

Cell and Tissue Culture Services

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In vitro Disease Models

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Functional & Cell Type Specific Assays

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DNA Sequencing

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DNA Sequencing Services

DNA Sequencing Services

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Illumina NextSeq 500 Illumina Illumina NextSeq

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Gastroenterology Animal Models

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Gastroenterology Animal Models Services

Gastroenterology Animal Models Services

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Nucleic Acid Analysis

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Nucleic Acid Analysis Services

Nucleic Acid Analysis Services

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RNA Sequencing

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Illumina NextSeq 500 Illumina Illumina NextSeq

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Pharmacology & Toxicology

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Animal Models of Disease

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Animal Models and Studies

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Microbiology

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Tissue Preparation

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DNA Services

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Cytometry

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Immunophenotyping

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Genotyping and Gene Expression Assays

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Drug Discovery & Development

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Drug Discovery & Development Services

Drug Discovery & Development Services

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Pharmacology

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Pharmacology Services

Pharmacology Services

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Flow Cytometry Data Analysis

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Toxicity Animal Models

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Mouse Rat Rodents

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Toxicology

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Toxicology Services

Toxicology Services

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In vivo Toxicity Testing

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In vivo Toxicity Testing Services

In vivo Toxicity Testing Services

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IBS/IBD Animal Models

Irritable Bowel Syndrome/Disease Animal Models
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Human Immune Cell Assays

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Tissue Microarrays

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RNA Amplification

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Immune Cell Assays

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Biospecimens

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Biology

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Biochemistry & Molecular Biology

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Virology Services

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Cell-Based Assays

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Biomarkers

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