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Envigo Crop Protection

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About Envigo Crop Protection

Divison of: Envigo

Scientific Excellence + Technical Superiority + Experienced Staff + A Partnership Mindset = Trusted Reliability for Chemical Testing Services

In your quest to develop effective new chemicals and procedures that make a significant difference in the lives of people, animals, crops, and the environment, your... Show more »

Scientific Excellence + Technical Superiority + Experienced Staff + A Partnership Mindset = Trusted Reliability for Chemical Testing Services

In your quest to develop effective new chemicals and procedures that make a significant difference in the lives of people, animals, crops, and the environment, your success relies on technical expertise, a robust suite of testing services, and a commitment to being your trusted partner. For the past 60 years, Envigo has supported companies like yours and we continue to maintain the highest standards of quality and customer service, offering a broad range of practical support, consultancy and problem solving, all of which can be customized to meet your specific research requirements.

As the leading chemical testing research organization, Envigo is committed to providing you with exactly what you need, from outsourced single studies, through managing complex programs, to the development of long-term strategic partnerships.

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Our Services (32)


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Endocrine Disruptor Screening

Price on request

From the beginning, we have been committed to helping you navigate your way through the endocrine disruptor screening program (EDSP) to obtain a successful outcome. Envigo hit the ground running as soon as the EDSP was announced by the U.S. Environmental Protection Agency (EPA), and we remain in the forefront of EDSP testing. ... Show more »

From the beginning, we have been committed to helping you navigate your way through the endocrine disruptor screening program (EDSP) to obtain a successful outcome. Envigo hit the ground running as soon as the EDSP was announced by the U.S. Environmental Protection Agency (EPA), and we remain in the forefront of EDSP testing. We started validation of the required tests as soon as the EPA regulations and requirements were published, and all our EDSP studies continue to be fully accepted by the EPA.

We can ally with you at all points in the EDSP process by answering your questions, helping you to arrive at a strategy, providing testing and giving you the regulatory support you may need.

Our screening program comprises of two tiers of testing:
Tier one identifies the chemicals that have the potential to interact with the endocrine system.
Tier two determines the endocrine-related effects and establishes the dose at which the effects occur.

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Environmental Fate Studies

Price on request

In an increasingly complex regulatory arena environmental fate is a key part of your testing program. Envigo has over 30 years’ experience in this area conducting both laboratory and field studies including higher tier testing. Our experts are on hand to help you in designing bespoke studies to meet address modern... Show more »

In an increasingly complex regulatory arena environmental fate is a key part of your testing program. Envigo has over 30 years’ experience in this area conducting both laboratory and field studies including higher tier testing. Our experts are on hand to help you in designing bespoke studies to meet address modern challenges.

Our core services
Soil metabolism (aerobic, anaerobic and paddy)
Water/sediment metabolism (aerobic, anaerobic, irradiated)
Aerobic mineralization in surface water
Field soil dissipation, accumulation and leaching
Hydrolysis
Photodegradation in soil and water
Adsorption/desorption and column leaching
Environmental modelling
Metabolite identification

Our team
The environmental fate group at Envigo has unrivalled experience and expertise. We are proud of our problem-solving culture and work collaboratively with our customers to ensure a high quality experience. From study initiation through to issue of the final report, you can feel confident that the scientific management of your study is in safe hands.

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In vivo Genotoxicity Testing

Price on request

Accuracy, experience, reliability, and quality are critical in genetic toxicology services. At Envigo, these are the cornerstones of our partnership. For the past 30 years, our team of scientists has offered customers like you their expertise in all aspects of genetic toxicology. When you partner with Envigo, you tap into the... Show more »

Accuracy, experience, reliability, and quality are critical in genetic toxicology services. At Envigo, these are the cornerstones of our partnership. For the past 30 years, our team of scientists has offered customers like you their expertise in all aspects of genetic toxicology. When you partner with Envigo, you tap into the knowledge and experience that we have shared with customers who range from smaller development companies to large multinational corporations.

  • Ames test
  • Mouse lymphoma assay
  • Chromosome aberration test
  • In vitro micronucleus test
  • In vivo micronucleus test
  • Unscheduled DNA synthesis test (in vitro and in vivo)
  • Comet assay (in vitro and in vivo)
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Seed Testing

Price on request
Request a quote for more information about this service.

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Project Management

Price on request

Program management is at the center of all successful research and development. The best products and most rigorous studies will still always depend on the structured, transparent leadership of high quality program managers. With the need to rapidly progress through the development process while supporting regulatory submissions... Show more »

Program management is at the center of all successful research and development. The best products and most rigorous studies will still always depend on the structured, transparent leadership of high quality program managers. With the need to rapidly progress through the development process while supporting regulatory submissions and mitigating study risk, you need a Program Manager who is fully dedicated to your success and understands how to flawlessly manage your development program.

Envigo is home to many senior scientists who are very active in our industry, and they are anxious to work with you to help you successfully execute your research. Envigo program managers offer a depth and breadth of expertise in the chemical industry that you can leverage as you scan the environment, assess your products and programs, and make decisions about how to proceed both internally and with regulators.

Among their skills sets are their abilities to act as a focal point of contact when required. They have experience coordinating projects, monitoring progress and ensuring effective communications internally, externally and across programs. You can be sure that the knowledge and experience you are gaining in each part of your program also benefits your entire program. By keeping a firm grasp of the details within the big picture, our program managers are able to help shepherd your project from inception to completion.

  • Awareness of scientific issues that require expert input and discussion
  • Communication of issues to customer and management that may impact project objectives
  • Ability to adapt the involvement of the program director to meet the customer’s needs and demands of the program Interpretation of unexpected/unusual results and advice on further investigations
  • Production of independent expert position papers
  • Discussions and negotiation with regulators
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Regulatory Affairs Consulting

Price on request

Our consultants have helped customers develop and defend safe and effective new plant protection products that have made a real difference to people’s lives around the world. We offer a comprehensive range of high quality consulting services to the crop protection industry developing and registering both chemical and biological... Show more »

Our consultants have helped customers develop and defend safe and effective new plant protection products that have made a real difference to people’s lives around the world. We offer a comprehensive range of high quality consulting services to the crop protection industry developing and registering both chemical and biological based crop protection solutions for the global marketplace.

On behalf of our customers Envigo has registered as many active substances and plant protection products as some of the largest global crop protection companies over the last 10 years. We have helped our customers satisfy regulations worldwide including those for the EU, EPA, JMAFF and OECD, so that means we can be with you in whichever geography you are looking to register your product. Envigo is a unique organization as it combines independent consultancy and renowned testing capacities all in one place and as such you will have access to unrivalled scientific and regulatory expertise to ensure all requirements are met for your crop protection submissions.

Our core services Regulatory strategy Data gap reviews Dossier preparation, submission and support In silico assessments Hazard, exposure and risk assessments, including both human and environmental Discussion, liaison and negotiation with authorities Independent expert waivers and position papers Post-submission support.

Your crop protection product has the potential to offer significant benefit to your company and the market if you can swiftly and easily pass through the regulatory gauntlet. Whether you need regulatory advice, strategy, dossier preparation, risk assessment, or guidance on study requirements, Envigo is here to support you. As one of the world’s leading Contract Resource Organizations for the development and registration of crop protection products, Envigo has helped our customers satisfy regulations and register products worldwide including in the EU, EPA, JMAFF and OECD.

  • Regulatory consultancy and strategy development
  • Dossier preparation, submission and support
  • Risk assessment, including both human and environmental
  • Discussion, liaison and strategy development with authorities
  • Post-submission support
  • Product registration maintenance
  • Classification, labeling and safety data sheets
  • Only Representative service for REACH
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Consulting

Price on request

The most successful studies depend on open communication, scientific expertise, optimal resource allocation, and a commitment to proactive program management. Envigo offers a consultancy and program management service comprising our senior scientists who harness years of experience to play an active role in driving your... Show more »

The most successful studies depend on open communication, scientific expertise, optimal resource allocation, and a commitment to proactive program management. Envigo offers a consultancy and program management service comprising our senior scientists who harness years of experience to play an active role in driving your initiative within the industry.

Our experts understand what needs to be done, who needs to do it, and when it needs to happen. And they are experienced in having those critical conversations with you to help you reach your program objectives on time and on budget.

Envigo technical program management experts can act on a limited basis or across your entire program. Also, our program managers can act as a focal point of contact for you when you need it. We are able to coordinate your project by monitoring progress and ensuring effective communications internally and externally. We enable exchange of knowledge and experience among study directors to facilitate the conduct of the studies.

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In vitro Drug Safety Evaluation

Price on request

Chemical in vitro safety assessments are an important part of your product’s safety profile and critical to the health of the planet. We share your commitment to the environment and understand that in vitro safety assessment cannot be compromised. When you partner with Envigo, you gain more than 20 years’ experience with in vitro... Show more »

Chemical in vitro safety assessments are an important part of your product’s safety profile and critical to the health of the planet. We share your commitment to the environment and understand that in vitro safety assessment cannot be compromised. When you partner with Envigo, you gain more than 20 years’ experience with in vitro safety testing. We offer a comprehensive service for in vitro safety assessment of crop protection products. We also have a dedicated Chemical Registration Services Group offering specialists for in silico and WOE evaluation of in vitro testing requirements.

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Product Development, Testing, and Packaging

Price on request

Product Chemistry

Is your product unique or challenging? Does it require a more adaptable approach to chemistry testing? At Envigo, we combine scientific expertise with flexibility to develop novel testing methods that best fulfill your regulatory requirements. The Envigo organization has more than 50 years experience... Show more »

Product Chemistry

Is your product unique or challenging? Does it require a more adaptable approach to chemistry testing? At Envigo, we combine scientific expertise with flexibility to develop novel testing methods that best fulfill your regulatory requirements. The Envigo organization has more than 50 years experience testing a wide range of substances and products in different markets. This experience has enabled us to provide a proactive and more adaptable approach to your study needs. We have helped customers like you satisfy regulations throughout the world including in the EU, EPA, JMAFF and OECD.

  • Technical active ingredient characterization
  • Physical and chemical properties of active ingredients
  • Physical, chemical and technical characteristics of formulations
  • Formulation storage stability
  • Product certification for active ingredient content, including method validation
  • Expert review of data for submission to regulatory authorities
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In vitro Genotoxicity Testing

Price on request

Accuracy, experience, reliability, and quality are critical in genetic toxicology services. At Envigo, these are the cornerstones of our partnership. For the past 30 years, our team of scientists has offered customers like you their expertise in all aspects of genetic toxicology. When you partner with Envigo, you tap into the... Show more »

Accuracy, experience, reliability, and quality are critical in genetic toxicology services. At Envigo, these are the cornerstones of our partnership. For the past 30 years, our team of scientists has offered customers like you their expertise in all aspects of genetic toxicology. When you partner with Envigo, you tap into the knowledge and experience that we have shared with customers who range from smaller development companies to large multinational corporations.

  • Ames test
  • Mouse lymphoma assay
  • Chromosome aberration test
  • In vitro micronucleus test
  • In vivo micronucleus test
  • Unscheduled DNA synthesis test (in vitro and in vivo)
  • Comet assay (in vitro and in vivo)
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Environmental Science

Price on request

Whether you are focused on aquatic, avian, or terrestrial toxicology, your goal is to quickly and confidently determine if your product is safe. We share your dedication to the environment and understand your need to ensure that ecotoxicology studies reveal the most reliable information for your product. When you work with the... Show more »

Whether you are focused on aquatic, avian, or terrestrial toxicology, your goal is to quickly and confidently determine if your product is safe. We share your dedication to the environment and understand your need to ensure that ecotoxicology studies reveal the most reliable information for your product. When you work with the Envigo organization, you can have the confidence that more than 25 years of experience in a wide range of ecotoxicology studies will secure the potential of your project. As your partner, we offer you access to our state-of-the-art facilities including our purpose-built avian facility with incubation room and hatchery, our high-spec aquatic toxicology facilities, and our outdoor facility which incorporates 32ft2 microcosms and more than 60 ditch units.

Our knowledge and expertise in ecotoxicology is backed by 1000 terrestrial studies conducted in the last six years alone, including almost 200 avian studies.

  • Aquatic toxicology
  • Avian toxicology
  • Biodegradation
  • Terrestrial ecotoxicology
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Inhalation Toxicology

Price on request

Your study may be the first of its kind, requiring not just an experienced partner, but also one who is willing to collaborate with you to determine a novel optimal solution. At Envigo, we apply our diverse expertise conducting inhalation studies in both common and uncommon laboratory species to help you achieve your objectives.... Show more »

Your study may be the first of its kind, requiring not just an experienced partner, but also one who is willing to collaborate with you to determine a novel optimal solution. At Envigo, we apply our diverse expertise conducting inhalation studies in both common and uncommon laboratory species to help you achieve your objectives. Backed by more than 40 years of experience, we are accomplished in conducting all types of studies from standard OECD, JMAFF and OPPTS designs including the following:

  • Acute to two-generation reproductive studies
  • Cardiotoxicity to assessing anesthetic potential
  • Studies with specific approaches and dosing up to 24 hours/day

Tell us your challenge and then we’ll work with you to choose the appropriate solution.

Analytical Techniques

  • Online real time GC, IR and compound specific analyses with validated software
  • UPLC and HPLC analysis
  • Compound specific analysis

Species Available
- Rat
- Mouse
- Dog
- Rabbit
- Guinea pig
- Hamster
- Minipig
- Pygmy goat
- Cow

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DART Studies

Developmental and Reproductive Toxicology Studies
Price on request

As you prepare for registration and market authorization, your reprotoxicology studies are a critical component that must be conducted flawlessly. To whom will you turn for research support that combines expertise with a commitment to meeting your unique study objectives? When you partner with Envigo, you have access to more... Show more »

As you prepare for registration and market authorization, your reprotoxicology studies are a critical component that must be conducted flawlessly. To whom will you turn for research support that combines expertise with a commitment to meeting your unique study objectives? When you partner with Envigo, you have access to more than 40 years of work in the field of reprotoxicology backed by our breadth of experience with pharmaceuticals and biologicals. You can choose from a comprehensive package of studies, all performed in our fully AAALAC-accredited labs.

Our Core Services:

  • Study designs for non-pharmaceuticals
  • Dosing by all oral (dietary or gavage), dermal and inhalation routes
  • Extensive, proven behavioral testing
  • Fetal pathology including Wilson’s sectioning and microdissection techniques, staining for bone and cartilage
  • Computer-assisted sperm assessment (CASA)
  • Specialist neuropathology and morphometric measurements of the brain
  • Specialist pathology of male and female reproductive organs

We also offer consultancy services in reproductive studies and reproductive pathology.

Our reprotoxicology department is led by a large team of study directors and senior scientists supported by dedicated inhalation specialists, behavioral specialists, animal technicians with special reprotoxicology training, repro necropsy specialists and fetal pathologists. More than half our scientific staff members have at least 10 years of relevant experience. - See more at: http://www.envigo.com/products-services/chemical/reprotoxicology/#sthash.kvvhvG2a.dpuf

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Toxicology

Price on request

For your toxicology services, you rely on expertise, reliability of data, and proactive project management. Whether you are conducting genetic toxicology, ecotoxicology, reprotoxicology, or any number of other safety assessments, you need a collaborative, experienced partner focused on your success. Envigo has a distinguished... Show more »

For your toxicology services, you rely on expertise, reliability of data, and proactive project management. Whether you are conducting genetic toxicology, ecotoxicology, reprotoxicology, or any number of other safety assessments, you need a collaborative, experienced partner focused on your success. Envigo has a distinguished heritage of companies that have performed at least 1,500 studies per year for the past half century. We offer you a state-of-the-art toxicology infrastructure, including market-leading inhalation facilities and infusion capabilities.

You will have access to:

  • Dedicated inhalation and reproductive teams
  • In-life data capture via Xybion
  • AAALAC accreditation
  • 32 successful GLP inspections in the past ten years
  • 27 successful US FDA inspections globally in the past twenty years
  • Continued environmental enrichment initiatives
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Safety Pharmacology

Price on request
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Regulatory Affairs Services

Price on request
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Crop Field Trials

Price on request

Our core services
Field Trials
Raw agricultural commodities (RAC) trials
Processed commodity trials
Soil dissipation/accumulation studies
Dislodgeable foliar residue trials
Operator exposure
Field environmental fate
Field ecotoxicology

Our core services
Field Trials
Raw agricultural commodities (RAC) trials
Processed commodity trials
Soil dissipation/accumulation studies
Dislodgeable foliar residue trials
Operator exposure
Field environmental fate
Field ecotoxicology

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Agricultural Discovery & Development

Price on request
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Agricultural Field Studies & Operations

Price on request

Field Studies & Operations Services

Field Studies & Operations Services

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Agriscience

Price on request
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Pharmacology & Toxicology

Price on request
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Geological Sciences

Price on request
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Process Consulting

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Terrestrial Toxicity Testing

Price on request

Terrestrial Toxicity Testing Services

Terrestrial Toxicity Testing Services

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Ecotoxicity Testing

Price on request

Ecotoxicity Testing Services

Ecotoxicity Testing Services

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In vivo Toxicity Testing

Price on request

In vivo Toxicity Testing Services

In vivo Toxicity Testing Services

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In vitro Toxicity Testing

Price on request

In vitro Toxicity Testing Services

In vitro Toxicity Testing Services

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Drug Discovery & Development

Price on request

Drug Discovery & Development Services

Drug Discovery & Development Services

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QSAR Studies

Quantitative Structure-Activity Relationship Studies
Price on request

At Envigo we know that meaningful in silico predictions can only be made by people who understand the chemistry, toxicology and the statistical basis behind the models. Envigo is proud of our team of experts who have many years’ experience in conducting (Q)SARs and read-across and the understanding of the regulatory requirements.... Show more »

At Envigo we know that meaningful in silico predictions can only be made by people who understand the chemistry, toxicology and the statistical basis behind the models. Envigo is proud of our team of experts who have many years’ experience in conducting (Q)SARs and read-across and the understanding of the regulatory requirements. We are in frequent communication with academia and software providers in order to improve our service.

Our suite of (Q)SAR models consists of:
Biovia Discovery Studio (TOPKAT) 4.5 extensible
OECD Toolbox 3.3
DEREK Nexus 5.0.1
MultiCASE Ultra
VEGA NIC 1.1.1
US EPA T.E.S.T. 4.1
US EPA EPI Suite 4.11
ToxRead
ToxTree

As the predictions are made our expert team will assess the quality and confidence of the results. Depending on the endpoint we may recommend using different types of predictive models. Envigo has been providing in silico and read-across services for many years,
for predicting toxicity of impurities or metabolites in pesticide registrations
as part of our REACH services
for cosmetics and pharmaceuticals
or in the early stage of a client’s product development.

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Pesticide Residue Testing

Price on request

Residue analytical services
Industry leading, multi-skilled scientific expertise with extensive experience of broad service offering
Method development, method transfer and method validation
Full range LC-MS/MS and GC-MS/MS instruments including Sciex API 6500
Dedicated sample preparation team using facilities fully equipped for... Show more »

Residue analytical services
Industry leading, multi-skilled scientific expertise with extensive experience of broad service offering
Method development, method transfer and method validation
Full range LC-MS/MS and GC-MS/MS instruments including Sciex API 6500
Dedicated sample preparation team using facilities fully equipped for high sample throughput
Independent laboratory validation
Mobile analytical support working on operator exposure studies
Experienced Study Directors and Principal Investigators
Fast turnaround of studies

Our technical staff
Our Field Trials and residue analysis teams are comprised of agronomical experts and dedicated field operators with more than 20 years’ experience. Our study directors, based in both Northern and Southern Europe, are vastly experienced and each has at least 15 years’ experience within the agricultural research industry. The field team are supported by a large network across the Envigo business which includes Regulatory affairs, Program management, Environmental fate, Excotoxicology and Residue analytical services.

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Plant and Animal Metabolism Studies

Price on request

When you face your customers, competitors and regulators, you need to be assured that your compounds are safe and contribute to the well-being of the world’s food supply. With over 30 years of experience in conducting metabolism studies, Envigo can offer you that kind of assurance. From individual studies to full testing... Show more »

When you face your customers, competitors and regulators, you need to be assured that your compounds are safe and contribute to the well-being of the world’s food supply. With over 30 years of experience in conducting metabolism studies, Envigo can offer you that kind of assurance. From individual studies to full testing programs, our experts will work with you to design and deliver studies that fully meet your requirements.

Our core services
Plant metabolism
Confined rotational crop metabolism
Processing – nature of the residue
Livestock metabolism and nature of the residue (goats, cows, pigs, hens)
ADME
Dermal absorption (in vitro, in vivo)
Comparative in vitro metabolism
Metabolite identification

Our team
The metabolism group at Envigo has unrivalled experience and expertise. We are proud of our problem-solving culture and work collaboratively with our customers to ensure a high quality experience. From study initiation through to issue of the final report, you can feel confident that the scientific management of your study is in safe hands.

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Crop Protection Product Development

Price on request

We realize the tremendous challenges you are faced with every day within the biocide regulated market. You understand the market opportunities ahead although the route to registration and achieving sales revenue has become increasingly challenging. Envigo understands these challenges and can support you in achieving your goals. ... Show more »

We realize the tremendous challenges you are faced with every day within the biocide regulated market. You understand the market opportunities ahead although the route to registration and achieving sales revenue has become increasingly challenging. Envigo understands these challenges and can support you in achieving your goals. Our regulatory expertise, with comprehensive skills and understanding from the biocides and chemical industries, is supported by GLP accredited facilities and experienced scientific staff, enabling us to help guide your biocidal products to market within your timelines.

Our expertise includes:
Broad expert knowledge from regulatory specialists and expert consultants, analytical chemists, toxicologists, ecotoxicologists, environmental fate specialists, GLP laboratories, through to our own animal breeding facilities - a genuine one-stop capability to support your product registration.
Physico-chemical, stability, efficacy, toxicological, environmental fate and biodegradation testing
Non-animal alternatives including in silico methods
Risk assessment and exposure modelling of active substance product type combinations
Active substance notification
Biocidal product authorisation, project management and development of a testing strategy
Regulatory advice and support covering the BPR and transitional notification schemes
Submission support to ECHA’s ‘Register for Biocidal Products’
Competent authority negotiation and Article 95 representation and product defense
Consortia management and client representation

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