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Ensigna Biosystems, Inc.

Richmond, California, US

Ensigna Biosystems is a contract research organization that provides cutting-edge molecular pathology and genomic services to the biopharmaceutical industry. By combining traditional pathology services with genomics, Ensigna Biosystems is able to characterize biological samples based on protein expression, mRNA levels and mutational status, thus enabling the development of targeted therapies and the implementation of personalized medicine.

Please contact us to discuss the best possible shipping method that would be most suitable for your samples.

Ensigna Biosystems, Inc. has not listed any services.

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Immunohistochemistry (IHC)
Price on request

Antibody validation

Ensigna Biosystems recognizes that validation of antibodies for IHC is particularly challenging. To address this, we have put in place testing methods using cell pellets with known expression levels of the protein of interest. We validate commercial antibodies or your own custom antibodies (polyclonal or... Show more »

Antibody validation

Ensigna Biosystems recognizes that validation of antibodies for IHC is particularly challenging. To address this, we have put in place testing methods using cell pellets with known expression levels of the protein of interest. We validate commercial antibodies or your own custom antibodies (polyclonal or monoclonal). We undertake the entire process, including the generation of controls, the screening of antibodies and the optimization of the IHC assay.
Our approach exceeds the highest standards practiced in the industry. Please contact us so we can discuss our approach in details and tailor it to your needs.

We have validated protocols for P-Erk and P-Mek. Please inquire for other antibodies.


High Throughput IHC

Ensigna Biosystems uses two automated IHC platforms, the Discovery XT® (Ventana Medical Systems) and the intelliPATH® (Biocare Medical). In addition, we have the capability to construct in-house Tissue Microarrays (TMA) containing control cell pellets and tissues. This allows us to undertake high-throughput IHC studies with a fast fast turn-around time for your research projects.

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Agilent DAKO
VENTANA Discovery XT
Biocare Medical intelliPATH
Biocare intelliPATH
In situ Hybridization (ISH)
In Situ Hybridization
Price on request

In situ hybridization is a very effective method to detect genetic abnormalities and gene expression levels in cells and tissues. We offer a variety of services using fluorescent and chromogenic DNA and
RNA ISH.

Ensigna Biosystems is now a certified RNAscope® service provider. RNAscope ® is a novel multiplex nucleic acid in... Show more »

In situ hybridization is a very effective method to detect genetic abnormalities and gene expression levels in cells and tissues. We offer a variety of services using fluorescent and chromogenic DNA and
RNA ISH.

Ensigna Biosystems is now a certified RNAscope® service provider. RNAscope ® is a novel multiplex nucleic acid in situ hybridization technology based on Advanced Cell Diagnostics's patented probe design and signal amplification methodology.

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VENTANA Discovery XT
RNAscope
Biocare intelliPATH
Fluorescence in situ Hybridization (FISH)
Price on request
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VENTANA Discovery XT
Biocare intelliPATH
Whole Slide Imaging
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Bright-field whole slide scanning with a fast turn around time, and cloud-based pathology image storage and management. Your data will be stored in a secure web-based system and can be accessed by you from anywhere with the internet connection.

Bright-field whole slide scanning with a fast turn around time, and cloud-based pathology image storage and management. Your data will be stored in a secure web-based system and can be accessed by you from anywhere with the internet connection.

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VENTANA Discovery XT
Biocare intelliPATH
Image Analysis
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VENTANA Discovery XT
Biocare intelliPATH
Biomarker Analysis
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VENTANA Discovery XT
Biocare intelliPATH
IHC-positive Hybridoma Screening
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VENTANA Discovery XT
Biocare intelliPATH
Pathology Reports
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VENTANA Discovery XT
Biocare intelliPATH
Tissue Microarrays
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VENTANA Discovery XT
Biocare intelliPATH
Antibody Condition Optimization
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VENTANA Discovery XT
Biocare intelliPATH
Immunofluorescence
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VENTANA Discovery XT
Biocare intelliPATH
Mammalian Cell Culture
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VENTANA Discovery XT
Biocare intelliPATH
RNA Extraction
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VENTANA Discovery XT
Biocare intelliPATH
RNA Sequencing
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Genomic Services

Molecular characterization of tumor samples at the genomic level is an essential part of oncology drug discovery. Ensigna Biosystems offers genomic analysis to complement our pathology services. Gene signatures, mutations, chromosomal rearrangements are ways to characterize tumors beyond their histological... Show more »

Genomic Services

Molecular characterization of tumor samples at the genomic level is an essential part of oncology drug discovery. Ensigna Biosystems offers genomic analysis to complement our pathology services. Gene signatures, mutations, chromosomal rearrangements are ways to characterize tumors beyond their histological classification and are playing an increasing role in choosing therapeutic options.
RNA/DNA extractions from frozen cells and tissues, blood, and formalin-fixed paraffin-embedded (FFPE) tissues
RNA/DNA quantification (UV and fluorescence based),
RNA/DNA analysis (QC) by Bioanalyzer
Gene expression analysis by TaqMan®, NanoString®, microarray or RNAseq
Genetic characterization by targeted sequencing using NGS technology.

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VENTANA Discovery XT
Biocare intelliPATH
Western Blot
Price on request
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VENTANA Discovery XT
Biocare intelliPATH
ELISA
Enzyme-linked immunosorbent assay
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VENTANA Discovery XT
Biocare intelliPATH
Cryoembedding
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VENTANA Discovery XT
Biocare intelliPATH
Cryosectioning
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VENTANA Discovery XT
Biocare intelliPATH
Special Slide Staining
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VENTANA Discovery XT
Biocare intelliPATH
Paraffin Sectioning
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VENTANA Discovery XT
Biocare intelliPATH
Tissue Preparation
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VENTANA Discovery XT
Biocare intelliPATH
Histopathological Examination
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VENTANA Discovery XT
Biocare intelliPATH
H&E Staining
Hematoxylin and eosin staining
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Leica Autostainer XL hematoxylin and eosin stainer
VENTANA Discovery XT
Biocare intelliPATH
In vitro PK/PD Models
In vitro pharmacokinetics/pharmacodynamics
Price on request

Pharmacodynamic Marker Discovery

Pharmacodynamic Marker Discovery

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VENTANA Discovery XT
Biocare intelliPATH
Coverslipping
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Agilent DAKO
VENTANA Discovery XT
Biocare intelliPATH
Formalin Fixation
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VENTANA Discovery XT
Biocare intelliPATH
Assay Development
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VENTANA Discovery XT
Biocare intelliPATH
High Throughput Screening (HTS)
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VENTANA Discovery XT
Biocare intelliPATH
Project and Process Management
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Experimental Design
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Clinical Research
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Clinical Laboratory Services
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Clinical and Anatomic Pathology
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Histological Staining
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Common Histochemical Stains
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Biology
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Cells and Tissues
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Biospecimens
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Tissue Processing
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Tissue Embedding
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Tissue Fixation
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Tissue Sectioning
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Biochemistry & Molecular Biology
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Protein Services
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Protein Expression Visualization
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Immunostaining
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Protein Quantification
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Antibody Services
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Therapeutic Monoclonal Antibody (mAb) Development
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Nucleic Acid Services
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DNA Services
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DNA Hybridization
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RNA Services
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Imaging & Spectroscopy
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Microscopy
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Pharmacology & Toxicology
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Bioanalysis
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Biomarkers
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ADME/DMPK Studies
Drug Metabolism and Pharmacokinetics
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Drug Discovery & Development
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Drug Discovery
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Hit Identification
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Computational Modeling
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Data Services
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2018-08-13 07:55:52 -0700

Net Promoter Score of 8 received for Immunohistochemistry (IHC).

Additional Ratings: satisfaction with deliverable: 8,
2018-08-13 06:16:46 -0700

Net Promoter Score of 9 received for Immunohistochemistry (IHC).

Additional Ratings: satisfaction with deliverable: 9, satisfaction with timeliness: 9.
2018-07-10 08:57:41 -0700

Net Promoter Score of 10 received for Protein Services.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
March 23, 2018

Positive review received for Whole Slide Imaging:

"Fast turnaround w/ quality communication and help along the way"

2018-03-21 15:27:19 -0700

Net Promoter Score of 8 received for Whole Slide Imaging.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 8.
2018-01-02 07:24:30 -0800

Net Promoter Score of 10 received for Mammalian Cell Culture.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
January 2, 2018

Positive review received for Mammalian Cell Culture:

"Very knowledgeable, quick response and turn around time"

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