Dualsystems Biotech is a provider of proteomics services for industry and academia. The technology platforms are directed to identify intracellular as well as extracellular drug targets. Our specialities LRC-TriCEPS™, ligand-receptor capture (CaptiRec) and CaptiVate make use of mass spectrometry analysis of protein complexes.
Now available: The next generation of LCR-TriCEPS
TriCEPSTM V.3.0 enables receptor identification for your orphan ligands at the surface of living cells without genetic manipulation. Key features of the new TriCEPSTM V.3.0 and LRC- TriCEPSTM technology are:
Decoding the extracellular interactome using LRC-TriCEPS™
A novel approach to analyse extracellular cell signaling by discovering cell surface receptors and off-targets for a ligand of interest on the living cell: label ligand with the LRC-TriCEPS™crosslinker, incubate with living cells or tissue expressing target receptor(s), purify receptor crosslinked peptides, analyse by LC-MS/MS. This new technology was invented by Andreas Frei and Bernd Wollscheid from the ETH Zurich who published the technology in Nature Biotechnology (Frei et al.(2012) Nature Biotechnology 30:997-1001).
Dualsystems Biotech AG, is a biotech company that provides services to analyse protein-protein interactions.
Identification of protein complexes and protein interactions in mammalian cells using a tagged bait
CaptiVate Shotgun Proteomics Services using LC-MS/MS
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