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DevLab

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Cleveland, Ohio, US

About DevLab

DevLab, LLC is a Contract Research Organization founded in 2018 with facilities in Cleveland, Ohio. DevLab provides a full suite of resources from project management to product development to produce products and assays from your proven technology. Our experienced team can initiate projects quickly, reduce risks and avoid unnecessary costs. DevLab endeavors to...

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DevLab, LLC is a Contract Research Organization founded in 2018 with facilities in Cleveland, Ohio. DevLab provides a full suite of resources from project management to product development to produce products and assays from your proven technology. Our experienced team can initiate projects quickly, reduce risks and avoid unnecessary costs. DevLab endeavors to provide start-ups, small and mid-size companies the necessary resources to commercialize concepts, produce and market new products. We provide development and commercialization services and support from concept to prototype, from prototype to product and from product to commercialization. We also provide a comprehensive services suite including Molecular Diagnostics, Immunoassay and Antibody processing and development services. Through partnerships, we provide a route to FDA approval. Unlike the traditional CRO, we assist with experimental design and have the facilities and capabilities to take a customer's idea from concept to commercialization in a variety of disciplines. Our commercialization support includes evaluating technologies, scientific and product expertise support, project management and laboratory facilities for building and testing products. DevLab provides business infrastructure and marketing guidance. We provide IP support and operate with regulatory expertise in CAP/CLIA, GLP/GMP and ISO compliance.

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Diversity Certificates

Small business

Our Services (18)


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DNA Extraction

Price on request

DevLab offers DNA and RNA extractions for most sample types utilizing QIAGEN® extraction reagents, equipment and procedures.  Extractions are processed via manual protocols or by utilizing QIAGEN® EZ1 or QIAcube® instrumentation.  Most research sample types can be processed:

 

-... Show more »

DevLab offers DNA and RNA extractions for most sample types utilizing QIAGEN® extraction reagents, equipment and procedures.  Extractions are processed via manual protocols or by utilizing QIAGEN® EZ1 or QIAcube® instrumentation.  Most research sample types can be processed:

 

- Mammalian Cells
- Blood or Blood Components
- Blood Cards
- Tissue
- Paraffin-Embedded Tissue
- Formalin-Fixed Tissue
- Gram Negative and Positive Bacteria
- Saliva/Sputum
- Urine
- Stool
- Plant Material

 

All extracted material will be quantitated and normalized as needed for client specific downstream uses.  All extraction services will be performed under strict Good Laboratory Practices.

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RNA Extraction and Purification

Price on request

DevLab offers DNA and RNA extractions for most sample types utilizing QIAGEN® extraction reagents, equipment and procedures.  Extractions are processed via manual protocols or by utilizing QIAGEN® EZ1 or QIAcube® instrumentation.  Most research sample types can be processed:

 

-... Show more »

DevLab offers DNA and RNA extractions for most sample types utilizing QIAGEN® extraction reagents, equipment and procedures.  Extractions are processed via manual protocols or by utilizing QIAGEN® EZ1 or QIAcube® instrumentation.  Most research sample types can be processed:

 

- Mammalian Cells
- Blood or Blood Components
- Blood Cards
- Tissue
- Paraffin-Embedded Tissue
- Formalin-Fixed Tissue
- Gram Negative and Positive Bacteria
- Saliva/Sputum
- Urine
- Stool
- Plant Material

 

All extracted material will be quantitated and normalized as needed for client specific downstream uses.  All extraction services will be performed under strict Good Laboratory Practices.

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RT-PCR

Reverse transcription polymerase chain reaction
Price on request

Real-time PCR monitors the amplification of a targeted molecule in real time. This technique is used for sensitive, specific detection and quantification of nucleic acid targets. Real-Time PCR may be used for a diverse set of applications including gene expression, genetic variation analysis and mutation detection assays.... Show more »

Real-time PCR monitors the amplification of a targeted molecule in real time. This technique is used for sensitive, specific detection and quantification of nucleic acid targets. Real-Time PCR may be used for a diverse set of applications including gene expression, genetic variation analysis and mutation detection assays. DevLab utilizes ABI® 7900HT FAST Real-Time PCR system and SDS software to quantitate DNA and RNA extracts from various sample types. The DNA/RNA quantity is provided to the client in the desired format. Based on the detected quantities, DevLab can normalize sample extracts for downstream processing as needed. DevLab offers real-time PCR for several diverse applications including:

 

- Quantification of gene expression
- Diagnostic uses
- Detection of pathogens
- Quantification and genotyping for clinical uses

 

All real-time PCR services are developed and customized based on client’s specific project needs. All DevLab services are performed under strict Good Laboratory Practices.

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SNP Genotyping

Single Nucleotide Polymorphism Genotyping
Price on request

SNPs are one of the most common types of genetic variation. SNP genotyping is the measurement of genetic variations of single nucleotide polymorphisms (SNPs) between members of a species. A SNP is a single base pair mutation at a specific locus. DevLab utilizes Applied Biosystems TaqMan® SNP Genotyping... Show more »

SNPs are one of the most common types of genetic variation. SNP genotyping is the measurement of genetic variations of single nucleotide polymorphisms (SNPs) between members of a species. A SNP is a single base pair mutation at a specific locus. DevLab utilizes Applied Biosystems TaqMan® SNP Genotyping Assays using TaqMan 5´‑nuclease chemistry to amplify and detect specific polymorphisms in purified genomic samples. DevLab can perform SNP Genotyping for various applications including:

 

- Ascertain drug response
- Drug resistance
- Determine susceptibility to environmental factors such as toxins
- Determine risk of developing particular diseases
- Track the inheritance of disease genes within families

 

All SNP Genotyping services are developed and customized based on client’s specific project needs. All DevLab services are performed under strict Good Laboratory Practices.

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qRT-PCR

Quantitative reverse transcription polymerase chain reaction
Price on request

DevLab offers custom Expression Analysis services based on client’s specific needs and requirements. Currently, DevLab offers Expression Analysis via quantitative real time PCR of mRNA utilizing Life Technologies® Real Time PCR equipment (such as 7900HT Fast).  Most Research sample types can be... Show more »

DevLab offers custom Expression Analysis services based on client’s specific needs and requirements. Currently, DevLab offers Expression Analysis via quantitative real time PCR of mRNA utilizing Life Technologies® Real Time PCR equipment (such as 7900HT Fast).  Most Research sample types can be processed:

 

- Cells
- Tissue (Fresh or Frozen)
- Paraffin-Embedded Tissue
- Formalin-Fixed Tissue

 

Gene Expression Profiling - Next Generation Sequencing (NGS)- Coming Soon – Early 2020!!!

 

In early 2020, DevLab will be offering Expression Profiling for high-throughput analysis utilizing Illumina NGS equipment.  Most research sample types can be processed:

- Cells
- Tissue (Fresh or Frozen)
- Paraffin-Embedded Tissue
- Formalin-Fixed Tissue

 

All Gene Expression Analysis services are developed and customized based on client’s specific project needs. All DevLab services are performed under strict Good Laboratory Practices.

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Cell Lines

Price on request

DevLab offers a variety of stable cell line development services suitable for most research applications such as:

 

- Cell-based assay development
- Antibody or recombinant protein production
- Drug discovery assay development
- Gene editing studies

 

Starting from... Show more »

DevLab offers a variety of stable cell line development services suitable for most research applications such as:

 

- Cell-based assay development
- Antibody or recombinant protein production
- Drug discovery assay development
- Gene editing studies

 

Starting from immortalized suspension or adherent mammalian cells, DevLab can provide the following cell line development services:

 

- Transfection including CRISPR/Cas9 editing options
- Antibiotic selection
- Cloning by Fluorescence Activated Cell Sorting (FACS)
- Protein expression validation and clone screening by FACS, ELISA, or Western blot
- PCR confirmation of gene insertions or knock-outs

 

All cell line development work is performed under strict Good Laboratory Practices conditions.

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Cell Viability & Proliferation Assays

Price on request

Viability and proliferation studies are essential tools for evaluating the health of cell populations over time. Applications for cell viability and proliferation studies range from routine cell culture to functional assays and drug discovery. Using flow cytometry and microplate reader platforms, DevLab can provide viability... Show more »

Viability and proliferation studies are essential tools for evaluating the health of cell populations over time. Applications for cell viability and proliferation studies range from routine cell culture to functional assays and drug discovery. Using flow cytometry and microplate reader platforms, DevLab can provide viability and proliferation studies to match client needs. Our services include:

 

- Dye exclusion viability testing
- Metabolic viability testing
- Differentiation and tracking of cell populations over multiple generations
- Cell cycle analysis
- Apoptosis and necrosis analysis

 

All cell line development work is performed under strict Good Laboratory Practices conditions.

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Functional & Cell Type Specific Assays

Price on request

DevLab offers a wide range of functional assay testing to support the assay development process.  Our services include:

 

- Reporter gene assays

- Immune cell activation
- Cell lysis assays
- Cell marker expression analysis
- if Cytokine release
- CytotoxicityShow more »

DevLab offers a wide range of functional assay testing to support the assay development process.  Our services include:

 

- Reporter gene assays

- Immune cell activation
- Cell lysis assays
- Cell marker expression analysis
- if Cytokine release
- Cytotoxicity
 -Enzyme production

 

All cell line development work is performed under strict Good Laboratory Practices conditions.

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ELISA

Enzyme-linked immunosorbent assay
Price on request

ELISA (Enzyme Linked Immunosorbent Assay) is a commonly used biomolecular technique for the detection and quantification of antibodies, proteins, hormones or other molecules in a sample.  DevLab can assist in developing custom ELISAs for desired targets or provide ELISA screening of antibodies and antigens to support the... Show more »

ELISA (Enzyme Linked Immunosorbent Assay) is a commonly used biomolecular technique for the detection and quantification of antibodies, proteins, hormones or other molecules in a sample.  DevLab can assist in developing custom ELISAs for desired targets or provide ELISA screening of antibodies and antigens to support the assay development process.

All cell line development work is performed under strict Good Laboratory Practices conditions.

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Antibody Production

Price on request

DevLab offers monoclonal antibody production and purification from bacterial or mammalian production systems. These services include:

- Affinity purification
- Buffer exchange into a variety of buffers
- Final antibody quantitation
- Testing by SDS PAGE and Western blot to confirm purity
- ELISA or additional validation assays as requested.

DevLab offers monoclonal antibody production and purification from bacterial or mammalian production systems. These services include:

- Affinity purification
- Buffer exchange into a variety of buffers
- Final antibody quantitation
- Testing by SDS PAGE and Western blot to confirm purity
- ELISA or additional validation assays as requested.

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Enzyme-Linked Immunosorbent Spot

Price on request
Request a quote for more information about this service.

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Antibody Purification

Price on request
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Antibody Modification

Price on request
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Primer Extension Assay

Price on request
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PCR Primer Design

Price on request
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qPCR

Quantitative PCR
Price on request
Request a quote for more information about this service.

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DNA Profiling

Price on request
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RNA Amplification

Price on request
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Lisa Sutton

VP Business Development

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