DC3 Therapeutics, LLC

South San Francisco, California, US

DC3 Therapeutics is a full service Contract Research Organization (CRO). We offer a full set of services necessary for drug development. We can support Pre-Clinical and IND Enabling studies. Our team has extensive experience in drug development and the pharmaceutical industry.

DC3 Therapeutics began as a provider of histology services and we've expanded our capabilities to include standard and custom research solutions for biotechnology and clinical stage companies. Our services include histology, in vitro pharmacology and ADME; as well as molecular, cellular, and micro-biology. We are happy to work with our clients to tailor experimentation to their research and development goals and to have them rely on us to deliver quality data. For more complex pre-clinical programs, our expertise allows us to be a single point of contact so our clients can focus on their core business without having to manage multiple... Show more »

DC3 Therapeutics is a full service Contract Research Organization (CRO). We offer a full set of services necessary for drug development. We can support Pre-Clinical and IND Enabling studies. Our team has extensive experience in drug development and the pharmaceutical industry.

DC3 Therapeutics began as a provider of histology services and we've expanded our capabilities to include standard and custom research solutions for biotechnology and clinical stage companies. Our services include histology, in vitro pharmacology and ADME; as well as molecular, cellular, and micro-biology. We are happy to work with our clients to tailor experimentation to their research and development goals and to have them rely on us to deliver quality data. For more complex pre-clinical programs, our expertise allows us to be a single point of contact so our clients can focus on their core business without having to manage multiple CROs. We pride ourselves on our customer service: contact us for consultation on any of your research needs.

DC3 is committed to superior customer service. DC3 understands that drug development is a fast paced and demanding environment. We guarantee that our services will be performed accurately and with a fast turn-around time. To ensure a quick turn around each customer is assigned a secured DC3 account. This account can be used to download data, schedule pickups, and submit questions about data.

Plasmid Sequencing

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Plasmid DNA Preparation

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mRNA Sequencing

Price on request

RNA sequencing on Ion Torrent platform

RNA Extraction and Purification

Starting at $40.00 per unit

RNA isolation from cells in culture or tissue

cDNA Synthesis

Starting at $15.00 per unit

cDNA synthesis from isolated RNA for qRT-PCR

Cell Banking

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Cell Expansion

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Mammalian Cell Culture

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Label-Free Ligand Binding Assays

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Label-free Biophysical Characterization
Kinetic binding data and analysis
Dose-response curves

*Sample requirements: *
0.5-500 ng of material, 10-75uL of sample, 1-200 kDA

11-log dynamic range starting at 100 fM
Assays run on AGILE R100 by Nanomedical Diagnostics

Agile R100

Label-Free

Nanomedical Diagnostics Agile R100

In vitro ADME/DMPK Studies

Price on request

Microsomal stability (mouse, rat, dog, human)
S9 Stability
Plasma Stability
Solubility (thermodynamic and kinetic)
Protein Binding
Cyp induction
Transporter assay

Human

Mouse

Dog

QuantStudio 3

Ion Torrent Sequencing

Ion Torrent Next Generation Sequencing

Price on request

NGS sequencing on Ion Torrent S5XL.

QuantStudio 3

DNA Purification

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QuantStudio 3

Baculovirus/Insect Cell Protein Expression

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QuantStudio 3

Bacterial Protein Expression

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QuantStudio 3

Sanger Sequencing

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QuantStudio 3

Site-Directed Mutagenesis

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QuantStudio 3

Stable Cell Line Generation

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QuantStudio 3

Apoptosis Assays

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QuantStudio 3

Mycoplasma Testing

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QuantStudio 3

ADCC and CDC Assays

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QuantStudio 3

ELISA

Enzyme-linked immunosorbent assay

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QuantStudio 3

Custom Biochemical Assay Development

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QuantStudio 3

Luminex Multiplex Assays

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QuantStudio 3

Molecular Cloning

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QuantStudio 3

qRT-PCR

Quantitative reverse transcription polymerase chain reaction

Starting at $160.00 per plate

96 well or 384-well runs. Cost listed is for 96-well plate run

QuantStudio 3

Histology and Pathology Services

Price on request

Routine trimming, processing, and embedding of fixed and frozen tissue.
Serial and step sectioning of fixed and frozen tissue.
Special stains (H&E, Masson's Trichrome, PicoSirus Red, etc...).
Immunohistochemistry and Immunoflorescence (Including method development).

QuantStudio 3

Protein Production

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Bioanalysis

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Protein Quantification

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Clinical Laboratory Services

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Cell-Based Assays

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Protein Services

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Nucleic Acid Services

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DNA Services

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Cytotoxicity Assays

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Biology

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Testing of Cell Lines

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Mutagenesis

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Next Generation Sequencing (NGS)

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Pharmacology & Toxicology

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Cell Death Assays

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Cells and Tissues

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PCR

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Clinical and Anatomic Pathology

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DNA Extraction and Purification

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Biomolecular Interaction Analysis

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Biochemistry & Molecular Biology

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Toxicology

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DNA Sequencing

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Clinical Research

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Biochemical Assays

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Cell and Tissue Culture

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Cell and Tissue Culture Services

Biospecimens

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Biospecimens Services

Biospecimen Management and Storage

Price on request

Human Biospecimen Management and Storage Services

Competent Cell Production

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RT-PCR

Reverse transcription polymerase chain reaction

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Compound IC50 Assays

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Drug Discovery & Development

Price on request

Drug Discovery & Development Services

DNA Synthesis and Probe Development

Price on request

DNA Synthesis and Probe Development Services

RNA Services

Price on request

RNA Services

Enzyme-Linked Immunosorbent Spot

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Primer Extension Assay

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PCR Primer Design

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Immunoprecipitation

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Compound Profiling

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Drug Discovery

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Drug Discovery Services

Lead Identification and Validation

Price on request

Lead Identification and Validation Services

Enzyme Assays

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RACE

Rapid amplification of cDNA ends

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TaqMan Assays

TaqMan Gene Expression Assays

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Multigene Panel

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Clinical Molecular Diagnostics

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Clinical Molecular Diagnostics Services

Gene Panel Testing

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Gene Panel Testing Services

Whole Genome Sequencing

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Immunoassays

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Pharmacology

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Pharmacology Services

Bioanalytical Assays

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Bioanalytical Assays Services

Cell Lines

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Angiogenesis & Endothelial Cell Assays

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qPCR Data Analysis

Quantitative PCR Data Analysis

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PCR Product Purification

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SNP Discovery Sequencing

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Targeted Gene Sequencing

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In vitro Cardiotoxicity Screening

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In vitro Toxicity Testing

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In vitro Toxicity Testing Services

Drug Absorption Studies

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ADME/DMPK Studies

Drug Metabolism and Pharmacokinetics

Price on request

ADME/DMPK Studies Services

Histological Staining

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Protein-DNA Interaction Analysis

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Electrophysiology

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Protein Characterization

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Transfection

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Liquid Chromatography (LC)

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Chemistry and Materials

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Chemistry and Materials Services

Analytical Chemistry Services

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Analytical Chemistry Services

Separation/Purification Services

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Purification Services

Chromatography

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Chromatography Services

Lysate Production

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Genetic Engineering

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Microbiology

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Primary Cell Culture

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Plasmids and Vectors

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Plasmids and Vectors Services

2018-09-05 11:51:06 -1000

Net Promoter Score of 9 received for In vitro ADME/DMPK Studies.

Additional Ratings: satisfaction with deliverable: 9, satisfaction with timeliness: 9.

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