The RPCI Data Bank and BioRepository (DBBR) prospectively collects and provides de-identified biospecimens and associated epidemiological and clinical data to investigators with IRB approved protocols. Newly diagnosed patients are consented for collection of blood tubes, completion of a risk factor questionnaire, and permission to link their samples to clinical data. DBBR samples and data can also be paired with tumor tissue from the Pathology Resource Network. Additionally, non-patients (family members and friends of patients and community members) with no personal history of cancer are asked to participate in the DBBR as healthy volunteers.
The DBBR strives to provide specimens that are rigorously collected, processed and stored so that the integrity of potential analytes will be consistent across all patients and controls. When consented, orders for phlebotomy are placed in the hospital electronic system, and labels for DBBR blood tubes are printed when participants register in phlebotomy. Tubes are drawn and sent to the DBBR laboratory through the pneumatic tube system, for processing into serum, plasma, red blood cells, buffy coat, and DNA.
Specimens are centrifuged and the supernatant is automatically aliquoted using a MAPI robot from Cryobiosystem (parent company is IMV International corp., L'Aigle, France). The robotic system aliquots serum, plasma, buffy coat and red blood cells into inert plastic straws (0.5 mL each), seals each end and labels each straw with a barcode identifier. The straws are kept in a liquid nitrogen storage system developed by Cryobiosystem. In addition to the straws, whole blood, clot and buffy coat are aliquoted in 0.5mL barcoded cryovials and stored at -80. The standard time from collection to freeze for DBBR blood samples is one hour. For more information, please visit https://www.roswellpark.edu/shared-resources/data-bank-and-biorepository
Provision of serum, plasma, red blood cells, DNA and buffy coat, linked with clinical and risk factor data. Our samples are from cancer cases and controls. To read more about our bank go to https://www.roswellpark.edu/shared-resources/data-bank-and-biorepository
Data Bank and BioRepository has not received any reviews.
Data Bank and BioRepository has not received any endorsements.