Dante Labs

Your genome is your complete set of DNA. It is 3 billion letters long. Sequencing your whole genome gives you an unparalleled access to your health, your family traits, your life and much more.

• Average 30X coverage (industry standard depth)
  
• 99,7% SNP precision and sensitivity
  
• Clear and insightful report
  
• Raw data available (free of charge)

Cardiopathies are diseases of the heart. They affect the function of the heart and lead to serious illness.

Several forms of cardiomyopathies have an inherited base.

The Dante Labs Cardiopathies Panel identifies inherited gene faults that highly increase the risk of developing the most common heart diseases – that can lead to sudden death or other serious conditions.

This test includes the following gene markers: CACNA1C, CACNA2D1, CACNB2, CASQ2, CTNNA3, DSC2, DSG2, DSP, HCN4, KCNE1, KCNE2, KCNH2, KCNJ2, KCNQ1, LMNA, MYBPC3, MYH6, MYH7, MYL2, NKX2.5, PKP2, PLN, PRKAG2, RYR2, SCN10A, SCN5A, TMEM43, TNNI3, TNNT2, TRDN, TTR

Cystic fibrosis is a genetic disease that causes the body to generate thick and sticky mucus that clogs up the lungs. The digestive and the reproductive systems are also affected.

Cystic fibrosis is very common among people of Northern European ancestry.

Cystic fibrosis causes infertility in both men and women. At least 97% of men with cystic fibrosis are infertile.

The cause of the disease is a genetic mutation in the CFTR gene that encodes for the production of a defective protein instead a healthy one.

Dante Lab Cystic Fibrosis Genetic testing will read out the CFTR gene to screen for known mutational genetic variants of well characterized gene sets.

Cancer is the most common human genetic disease. All cancers are caused by mutations to specific genes.

Dante Labs Hereditary Cancer Test identifies gene faults inherited from parents that tremendously increase the risk of developing specific types of cancer.

This test includes the following gene markers: ATM, BRCA1, BRCA2, CDH1, CHEK2, NBN, PALB2, RAD51C, RAD51D, TP53, APC, BARD1, BRIP1, EPCAM, FAM175A, MLH1, MRE11A, MSH2, MSH6, MUTYH, PIK3CA, PMS2, PMS2CL, PTEN, RAD50, STK11, XRCC2

BRCA1 and BRCA2 are genes called tumor suppressor that work to protect our body against cancer. Their function is to keep breast, ovarian and other cells growing normally.

Everyone has BRCA1 and BRCA2, both men and women.

When either one of these two genes is mutated, people's chance of developing breast and ovarian cancer are greatly increased ( up to 80% for breast cancer, 60% for ovarian cancer).

Early detection of BRCA1 and BRCA2 mutations could allow the development of tailored approach and save your life.

Women with a mutated BRCA1 or BRCA2 gene also have an increased risk of developing ovarian, colon, and pancreatic cancers, as well as melanoma.

Men with an abnormal BRCA1 or BRCA2 have an higher risk of breast cancer, and an higher risk of developing prostate cancer.

About 1 in 300 people carry a BRCA1 mutation, and 1 in 800 carry a BRCA2 mutation.