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CXR Biosciences Ltd.

Dundee, GB

CXR Biosciences was established in 2001 and is based in Dundee, Scotland. We offer a range of services in toxicology and metabolism and work with customers ranging from individual academic labs, to new start biotechs to major multinational corporations which have included BASF, Bayer, Dow Agrochemical, DuPont, Monsanto, Syngenta, ExxonMobil, AstraZeneca, Sanofi-Aventis, Pfizer, Roche, Procter & Gamble, Ineos Group and 3M.

CXR Biosciences employs more than 35 staff from a range of industrial and academic backgrounds, more than 30% of whom hold PhDs. Our combination of academic excellence and extensive industrial experience in pharmaceutical, agrochemical and petrochemical toxicology as well as metabolism and pharmacokinetics leads to a uniquely skilled investigative toxicology and preclinical development service. Our services are supported with access to our own animal facility (rats and mice) and capabilities in... Show more »

CXR Biosciences was established in 2001 and is based in Dundee, Scotland. We offer a range of services in toxicology and metabolism and work with customers ranging from individual academic labs, to new start biotechs to major multinational corporations which have included BASF, Bayer, Dow Agrochemical, DuPont, Monsanto, Syngenta, ExxonMobil, AstraZeneca, Sanofi-Aventis, Pfizer, Roche, Procter & Gamble, Ineos Group and 3M.

CXR Biosciences employs more than 35 staff from a range of industrial and academic backgrounds, more than 30% of whom hold PhDs. Our combination of academic excellence and extensive industrial experience in pharmaceutical, agrochemical and petrochemical toxicology as well as metabolism and pharmacokinetics leads to a uniquely skilled investigative toxicology and preclinical development service. Our services are supported with access to our own animal facility (rats and mice) and capabilities in Agilent microarray.

CXR Biosciences specializes in a collaborative approach that helps our customers get the studies that exactly suit their needs and draw maximum possible value from the results. Whether your business is a new start venture or an established multinational, whether your concern is with selecting a drug candidate for onward development or with chemical safety of consumer products, CXR Biosciences is your contract research partner of choice for investigative and exploratory toxicology and metabolism studies.

CXR Biosciences is part of the discovery and preclinical division of the Concept Life Sciences Group.

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CXR Biosciences Ltd. has not listed any services.

Predictive toxicology
Price on request

Using a predictive toxicology approach, CXR can help you shift the identification of potential toxic hazard and risk from the development stage to the research stage of R&D

CXR uses a hypothesis-driven approach to review potential or observed toxicity issues, develop an experimental programme, and perform the required... Show more »

Using a predictive toxicology approach, CXR can help you shift the identification of potential toxic hazard and risk from the development stage to the research stage of R&D

CXR uses a hypothesis-driven approach to review potential or observed toxicity issues, develop an experimental programme, and perform the required experiments.

Results will be interpreted to understand translational risk assessment and/or drive chemical design and candidate selection. If required CXR will build and deploy novel mechanistic assays.

We have particular expertise in supporting exploratory and discovery programs in the agrochemical and pharmaceutical & biotech industries.

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Cytochrome P450 human
Mouse
Rat
PK/PD Modeling
Pharmacokinetics/Pharmacodynamics Modeling
Price on request

A full understanding of the metabolism of compounds is required in the biological systems to which the product will be exposed (for example as mandated by Regulation EC 1107/2009 for agrochemicals). CXR Biosciences routinely works with agrochemical, chemical and pharmaceutical companies to generate metabolic and pharmacokinetic /... Show more »

A full understanding of the metabolism of compounds is required in the biological systems to which the product will be exposed (for example as mandated by Regulation EC 1107/2009 for agrochemicals). CXR Biosciences routinely works with agrochemical, chemical and pharmaceutical companies to generate metabolic and pharmacokinetic / toxicokinetic profiling data for new products, data gap fill and update to new regulations to support resubmissions.

We routinely run comparative metabolism studies across a range of species, to establish metabolism kinetics and identify any potential species-specific major metabolites.

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In vivo Pharmacology Studies
Price on request

By understanding the pathways that define the sensitivity of organs and cells to chemicals, we explain observed toxicities and evaluate the actual hazard and risk to humans

We have extensive experience in evaluating toxicological processes across species, and determining the relevance to humans of observed adverse reactions to... Show more »

By understanding the pathways that define the sensitivity of organs and cells to chemicals, we explain observed toxicities and evaluate the actual hazard and risk to humans

We have extensive experience in evaluating toxicological processes across species, and determining the relevance to humans of observed adverse reactions to the satisfaction of regulatory bodies (hence this discipline is also known as explanatory toxicology).

CXR will work with you to design state of the art investigative safety studies to understand the mechanisms of adverse preclinical observations, interpret the results and, if required, make recommendations as to the future of the project.

Our expertise spans the agrochemical & chemical, pharmaceutical & biotechnology and consumer product industries.

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In vivo Protein Binding Assays
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Computational Modeling
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Biology
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Biomolecular Interaction Analysis
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Pharmacology & Toxicology
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ADME and DMPK Studies
Drug Metabolism and Pharmacokinetics
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In vivo PK/PD Studies
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Computational & Statistical Analysis
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Biochemistry & Molecular Biology
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