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Claire (Chunyan) Yao, PhD

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About Claire (Chunyan) Yao, PhD

Claire Yao is a Research Associate at the Institute of Health Food, Zhejiang Academy of Medical Sciences in Hangzhou City, China.

Her research interests focus on the evaluation and the mechanisms of antidepressant, antinociceptive, anxiolytic, antiaging activities in various animal and cell models, and the... Show more »

Claire Yao is a Research Associate at the Institute of Health Food, Zhejiang Academy of Medical Sciences in Hangzhou City, China.

Her research interests focus on the evaluation and the mechanisms of antidepressant, antinociceptive, anxiolytic, antiaging activities in various animal and cell models, and the extraction, isolation and enrichment of the bioactivity compounds and chronic and acute toxicity.

Yao received her PhD in Ecotoxicology Biodiversity Ecosystems and Pharmacognosy from Metz University, France and Fudan University, China, in 2010. Her MS in Biology was awarded by the School of Life Sciences, Northwest University, China, in 2005.

Yao's service capabilities involve research pharmacological effects and toxicity assessment of compounds and extracts from various medicinal plants in vivo and in vitro, in order to help pharmaceutical companies or some potential scientists outside the field of pharmacology to obtain experimental results quickly. She is particularly skilled in animal and cell models in pain, inflammation, depression, anxiety, hyperlipidemia, hyperglycemia, hypertension, memory, sleep, etc.

Recent Publications

  • Chunyan Yao, Ruiwen Hao, Shengli Pan and Yin Wang, 'Functional Foods Based on Traditional Chinese Medicine' in Nutrition, Well-Being and Health edited by Jaouad Bouayed and Torsten Bohn
  • Chunyan Yao, Jun Wang, Dong Dong, Fugang Qian, Jing Xie, Shengli Pan. Laetispicine, an amide alkaloid from Piper laetispicum, presents antidepressant and antinociceptive effects in mice. Phytomedicine, 16, 823-829 (2009)
  • Chunyan Yao, Wenzhe Liu. Seasonal Change of Anthraquinone in Vegetative Organs of Polygonum cuspidatum. Acta Botanica Borealia-Occidentalia Sinica, 25, 179-182 (in chinese) (2004)
  • H Xie, J Liu, M Yu, Y Wang, Chunyan Yao, et al. Structure-Activity Relationship of 39 Analogs of Laetispicine with Antidepressant Properties. The American Journal of Chinese Medicine, 41(6), 1377–1392 (2013)
  • Wei Li, Chunyan Yao, Ying Wang. Research progress on effect of nutrients and phytochemicals on NMDAR for improving cognition. Science and Technology of Food Industry, 33(23), 402-407 (2012)
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Our Services (29)


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Cell-Based Compound Screening

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Hypertension Animal Models

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Diabetes Animal Models

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Anxiety Animal Models

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  • Elevated Plus-Maze test
  • Light/Dark Preference
  • Y-maze
  • Hole board test
  • Elevated Plus-Maze test
  • Light/Dark Preference
  • Y-maze
  • Hole board test
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Acute Inflammation Animal Models

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  • paw edema
  • croton-oil ear edema
  • paw edema
  • croton-oil ear edema
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In vitro Inflammation Models

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LPS-induced inflammation in RAW 264.7 macrophages

LPS-induced inflammation in RAW 264.7 macrophages

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Depression Animal Models

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  • Forced swimming test
  • Tail suspension test
  • Chronic unpredicted mild stress
  • Forced swimming test
  • Tail suspension test
  • Chronic unpredicted mild stress
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Custom Pain Animal Models

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  • acetic acid writhing test
  • formalin test
  • hot plate test
  • acetic acid writhing test
  • formalin test
  • hot plate test
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In vivo Toxicity Testing

Price on request

We are professional in toxicology studies. We offer high-quality data and rapid turnaround period to support drug discovery and development. The toxicological studies are conducted in various animal species under non-GLP and/or GLP compliance.
Single and repeated dose toxicity study (rodent and non-rodent)

  1. LD50 study
    2.... Show more »

We are professional in toxicology studies. We offer high-quality data and rapid turnaround period to support drug discovery and development. The toxicological studies are conducted in various animal species under non-GLP and/or GLP compliance.
Single and repeated dose toxicity study (rodent and non-rodent)

  1. LD50 study
  2. 1-month to 9-month sub-chronic and chronic toxicity study
  3. Toxicokinetics study (rodent and non-rodent)
  4. Topical toxicity study
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In vitro Toxicity Testing

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MTT

MTT

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In vivo PK/PD Studies

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Animal Models and Studies

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Inflammation Animal Models

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In vitro Disease Models

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Drug Discovery

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Biology

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Pain/Neuropathy Animal Models

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Cognitive, Behavioral, and Psychiatric Animal Models

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Cytotoxicity Assays

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Toxicology

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Animal Models of Disease

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Immunology Animal Models

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Pharmacology & Toxicology

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Hit Identification

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Cells and Tissues

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Cardiovascular Animal Models

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Drug Discovery & Development

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ADME/DMPK Studies

Drug Metabolism and Pharmacokinetics
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Metabolic Animal Models

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