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CiToxLAB Inc.

Laval, Quebec, CA

CiToxLAB, our newly established group, created through the merger of CiT and LAB Research, provides a comprehensive range of preclinical and specialty services from our facilities in France, Canada, Denmark and Hungary. With a combined capacity in excess of 800 employees, 27 000 rodents, 5 000 non-rodents, including 1 200 non-human primates on-site, and purpose built facilities of 60 000 m2 (645, 000 ft2), the new group is a major global player in the preclinical outsourcing arena.

Our broad range of GLP and non GLP non-clinical services combined with our 40 years of experience is at the service of our customers to meet the demands of today’s complex global marketplace. We can provide you with accelerated product development, expansion into new markets, risk mitigation, reduced regulatory delays and improved quality. Reports from our four facilities have been successfully used by our clients in support of marketing... Show more »

CiToxLAB, our newly established group, created through the merger of CiT and LAB Research, provides a comprehensive range of preclinical and specialty services from our facilities in France, Canada, Denmark and Hungary. With a combined capacity in excess of 800 employees, 27 000 rodents, 5 000 non-rodents, including 1 200 non-human primates on-site, and purpose built facilities of 60 000 m2 (645, 000 ft2), the new group is a major global player in the preclinical outsourcing arena.

Our broad range of GLP and non GLP non-clinical services combined with our 40 years of experience is at the service of our customers to meet the demands of today’s complex global marketplace. We can provide you with accelerated product development, expansion into new markets, risk mitigation, reduced regulatory delays and improved quality. Reports from our four facilities have been successfully used by our clients in support of marketing authorization and new product approval submissions around the world, including to the European (EMA, ECHA), US (FDA and EPA) and Japanese (MHLW and MAFF) regulatory authorities.

CiToxLAB is committed to the humane treatment of the research animals entrusted to our care.

We guarantee they will be treated with the highest standards of respect and compassion, and particular attention is accorded to housing conditions, social interaction and enrichment of their environment. CiToxLAB’s ethics committees have established and rigorously enforce our ethics charter for Laboratory Animals. All employees must continuously demonstrate their commitment to animal welfare and are required to sign our ethics charter as a condition of initial and continuing employment.

Since 2004, our high ethical standards have been recognized by accreditation from the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC).

As a highly qualified service provider, we also strive to be flexible, accommodating and respond as quickly as possible to each of your individual needs.

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CiToxLAB Inc. has not listed any services.

Clinical Biomarkers
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Archive Management
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In vitro Cardiotoxicity Screening
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In vivo PK/PD Studies
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ADME is the evaluation of absorption, distribution, metabolism and excretion properties of compounds and their metabolites. We can help you develop ADME testing strategies spanning early stage development, preclinical toxicity and through your clinical trials.

The synergy within our group gives you a head start for competitive... Show more »

ADME is the evaluation of absorption, distribution, metabolism and excretion properties of compounds and their metabolites. We can help you develop ADME testing strategies spanning early stage development, preclinical toxicity and through your clinical trials.

The synergy within our group gives you a head start for competitive time-lines and efficient advice. You gain easy assess to our experts and we can evaluate your precise requirements and ensure you get the best ADME package at the best price.

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Custom Pain Animal Models
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In silico Cardiac Safety Assessment
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With today’s computer technology, we can offer predictive modelling for your drug candidates. This cost-effective technique is principally applicable for :

Impurity assessment : Pharmaceuticals generally contain low levels of impurities, the genotoxicity of which can be evaluated by in silico modelling.

With today’s computer technology, we can offer predictive modelling for your drug candidates. This cost-effective technique is principally applicable for :

Impurity assessment : Pharmaceuticals generally contain low levels of impurities, the genotoxicity of which can be evaluated by in silico modelling.

  • A wide range of genotoxicity endpoints can be assessed in parallel.

Results are interpreted against available preclinical data and intended clinical application. To make sure you get the best and most competitive solution, you will receive all necessary information in a format that is user-friendly and relevant to regulatory authority submission.

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VENTANA Discovery XT
Cobas analyzers (4000, 6000, or 8000)
Predictive Toxicology
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Understanding mechanisms of action and predicting toxicity in drug candidates can help you define the most efficient testing strategy. Predictive toxicology screening can highlight areas where candidate molecules have potential issues at a very early stage, facilitating drug candidate selection for further pre-clinical... Show more »

Understanding mechanisms of action and predicting toxicity in drug candidates can help you define the most efficient testing strategy. Predictive toxicology screening can highlight areas where candidate molecules have potential issues at a very early stage, facilitating drug candidate selection for further pre-clinical development.

Predictive toxicology screening for structuring formal testing packages; some examples:

  • Dermal screening for potential skin sensitisation and dermal irritation
  • QSAR for genotoxicity assessment
  • Toxicogenomics to assess potential hepatotoxicity

Our priority is accompanying you in your preclinical compound development, so we are always happy to advise you on drug candidate selection packages using our discovery and predictive toxicology services.

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VENTANA Discovery XT
Cobas analyzers (4000, 6000, or 8000)
QSAR Studies
Quantitative Structure-Activity Relationship Studies
Price on request

With today’s computer technology, we can offer predictive modelling for your drug candidates. This cost-effective technique is principally applicable for :

Drug candidate assessment : Based on the chemical structure and molecular substructure of tested compounds, each molecule is modelled by the computer-driven QSAR... Show more »

With today’s computer technology, we can offer predictive modelling for your drug candidates. This cost-effective technique is principally applicable for :

Drug candidate assessment : Based on the chemical structure and molecular substructure of tested compounds, each molecule is modelled by the computer-driven QSAR system.

  • QSAR analysis helps to understand the potential molecular dynamics between compounds under development and other chemical structures.

Results are interpreted against available preclinical data and intended clinical application. To make sure you get the best and most competitive solution, you will receive all necessary information in a format that is user-friendly and relevant to regulatory authority submission.

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VENTANA Discovery XT
Cobas analyzers (4000, 6000, or 8000)
In vitro ADME/DMPK Studies
Price on request

ADME is the evaluation of absorption, distribution, metabolism and excretion properties of compounds and their metabolites. We can help you develop ADME testing strategies spanning early stage development, preclinical toxicity and through your clinical trials.

The synergy within our group gives you a head start for competitive... Show more »

ADME is the evaluation of absorption, distribution, metabolism and excretion properties of compounds and their metabolites. We can help you develop ADME testing strategies spanning early stage development, preclinical toxicity and through your clinical trials.

The synergy within our group gives you a head start for competitive time-lines and efficient advice. You gain easy assess to our experts and we can evaluate your precise requirements and ensure you get the best ADME package at the best price.

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VENTANA Discovery XT
Cobas analyzers (4000, 6000, or 8000)
In vivo Pharmacology Studies
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Immunohistochemistry (IHC)
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VENTANA Discovery XT
Cobas analyzers (4000, 6000, or 8000)
Histopathological Examination
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VENTANA Discovery XT
Cobas analyzers (4000, 6000, or 8000)
High Throughput Screening (HTS)
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VENTANA Discovery XT
Cobas analyzers (4000, 6000, or 8000)
Ocular Toxicology
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VENTANA Discovery XT
Cobas analyzers (4000, 6000, or 8000)
Carcinogenesis Animal Models
Price on request

Including transgenic models –TgRas H2, p53 knockout, and TgAC

Including transgenic models –TgRas H2, p53 knockout, and TgAC

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VENTANA Discovery XT
Cobas analyzers (4000, 6000, or 8000)
Biomarker Analysis
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Drug Discovery
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Oncology Animal Models
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Computational Modeling
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Clinical Research
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Clinical Laboratory Services
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Biology
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Clinical Chemistry
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Protein Services
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Immunostaining
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Protein Expression Visualization
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Drug Discovery & Development
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Clinical and Anatomic Pathology
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In vivo Toxicity Testing
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Chemistry and Materials
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Biochemistry & Molecular Biology
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Animal Models of Disease
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Computational Chemistry
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Toxicology
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Project Management
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Pain/Neuropathy Animal Models
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Bioanalysis
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Antibody/Antigen Detection Based Testing
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Animal Models and Studies
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Hit Identification
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Biomarkers
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Pharmacology & Toxicology
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