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Cisbio US, Inc.

Bedford, Massachusetts, US

Cisbio International is a privately held innovative company committed to improving human healthcare with more than 50 years of experience in the fields of therapy, medical diagnostic and drug discovery fields.

As a company we are passionate about providing products and services of only the highest quality. What's more we take pride in offering added value to our clients through individual attention and collaborative partnerships providing creative solutions to the challenges they face. Our dedication to quality was initially put to use in the field of in vitro diagnostics where Cisbio developed the first products for radioimmunoassays. This fundamental principle is also demonstrated by our investment 20 years ago to establish in-house means of producing our own monoclonal antibodies for use in our diagnostic assays and more recently in our HTRF® product lines.

Our expertise in immunoassays was combined with... Show more »

Cisbio International is a privately held innovative company committed to improving human healthcare with more than 50 years of experience in the fields of therapy, medical diagnostic and drug discovery fields.

As a company we are passionate about providing products and services of only the highest quality. What's more we take pride in offering added value to our clients through individual attention and collaborative partnerships providing creative solutions to the challenges they face. Our dedication to quality was initially put to use in the field of in vitro diagnostics where Cisbio developed the first products for radioimmunoassays. This fundamental principle is also demonstrated by our investment 20 years ago to establish in-house means of producing our own monoclonal antibodies for use in our diagnostic assays and more recently in our HTRF® product lines.

Our expertise in immunoassays was combined with the results of Prof. Jean-Marie Lehn's research on rare earth fluorescence properties (Nobel prize in Chemistry, 1987) leading to the creation of HTRF® technology. Today, in conjunction with our extensive network of partners, the Cisbio R&D teams continue to develop HTRF® enhancements and new applications to meet the ever evolving needs of the scientific community.

We believe our background in immunoassay development, TR-FRET chemistry and quality manufacturing principles provide a unique combination of strengths that enables Cisbio to continually introduce innovative products.

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Cisbio US, Inc. has not listed any services.

Receptor Deorphanization
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Assay Development
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With Cisbio’s assay development services, you benefit from optimized assay solutions that make your experiments easier and more reliable. All operations are performed under strict confidentiality, with an end-to-end process from feasibility to development to transfer.

With Cisbio’s assay development services, you benefit from optimized assay solutions that make your experiments easier and more reliable. All operations are performed under strict confidentiality, with an end-to-end process from feasibility to development to transfer.

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Chemical Crosslinking/Bioconjugation
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We provide direct labeling on antibodies, peptides, small molecules, oligonucleotides, or just about any biomolecule of interest. Our promises:

  • Selection of the optimal fluorophore for your experiment
  • Fast turn-around time
  • Test size for assay development or proof-of-concept
  • Batch size with scaled-up implementation of... Show more »

We provide direct labeling on antibodies, peptides, small molecules, oligonucleotides, or just about any biomolecule of interest. Our promises:

  • Selection of the optimal fluorophore for your experiment
  • Fast turn-around time
  • Test size for assay development or proof-of-concept
  • Batch size with scaled-up implementation of large milligram quantities

Fluorophores and conjugation chemistry

Cisbio’s proprietary HTRF fluorophores include Europium and Terbium cryptates, and red-shifted acceptor donors d2 and XL665. Other fluorophores and tags are also available, including Biotin and DNP.

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Ligand Binding Assays
Price on request

Ligand binding assays for GPCR or RTK.
Cisbio offers services to test your compounds or samples on a wide range of assays using HTRF technology.
Determination of Kd and Ki values

Ligand binding assays for GPCR or RTK.
Cisbio offers services to test your compounds or samples on a wide range of assays using HTRF technology.
Determination of Kd and Ki values

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GPCR Assays
G-Protein Coupled Receptor Assay
Price on request

Cisbio offers kinetic studies for your compounds or samples on GPCR ligand binding assays using HTRF technology. Determination of Kd, Ki, Kon and Koff rates.

Cisbio offers kinetic studies for your compounds or samples on GPCR ligand binding assays using HTRF technology. Determination of Kd, Ki, Kon and Koff rates.

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Biopharmaceutical Development
Price on request

Cisbio offers service to test your biosimilar/biobetter samples on a wide range of FcGamma receptors (FcgR) and FcRn.

Cisbio offers service to test your biosimilar/biobetter samples on a wide range of FcGamma receptors (FcgR) and FcRn.

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HTRF
Homogeneous Time-Resolved Fluorescence
Price on request

Custom Antibody Labeling with HTRF Chemistry

Custom Antibody Labeling with HTRF Chemistry

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Optical Microscopy
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Antibody Services
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Receptor Assays
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Biochemical Assays
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Microscopy
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Fluorescence-Based Microscopy
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In vitro Bioavailability/Bioequivalence Studies
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Imaging & Spectroscopy
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Protein Services
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Project Management
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Biomolecular Interaction Analysis
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Biochemistry & Molecular Biology
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Oligonucleotide Ligation Assays
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Lysine Specific Demethylase-1 (LSD-1) Assays
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Human Double Minute 2 (HDM2) Assays
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Human Epidermal Growth Factor Receptor (HER/EGFR) Assays
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RAS Assays
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VEGF Signaling Assays
Vascular Endothelial Growth Factor Assays
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mTOR Assays
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Biology
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Cell-Based Assays
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Cell Signaling Analyses
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Enzyme Assays
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Kinase Assays
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Hydrolase Assays
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Ligase Assays
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Nucleic Acid Services
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DNA Services
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Genotyping Services
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Epigenetic Studies
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Drug Discovery & Development
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Drug Discovery & Development Services

Drug Discovery & Development Services

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Pharmacology
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Pharmacology Services

Pharmacology Services

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2018-07-31 15:44:27 -0700

Net Promoter Score of 10 received for Assay Development.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
July 15, 2016

Positive review received for GPCR Assays:

"Service was very timely. Report was thorough and covered all aspects described in the quote. Great experience."

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