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Chimera Biotec

Dortmund, DE

Chimera Biotec is a bioanalytical Contract Research Organization (CRO) and immunoassay platform provider specialized in ultra sensitive large-molecule bioanalysis and the worlds leading Immuno-PCR (IPCR) based technology vendor. Chimera Biotec provides great alternatives in bioanalytical CRO services.

The word "chimera" originates from Greek mythology, where a hybrid creature is composed of the bodyparts of multiple animals. In analogy, the core reagents in our proprietary Imperacer® immunoassay technology are chimeric antibody-DNA conjugates. Combining the specificity of antibody-target binding with exponential signal amplification of the DNA analysis, we provide ultra sensitivity. In preclinical support or limited study sample volume our ability to limit sample requirement to few microliter while still providing single digit pg/ml sensitivities can be very helpful, for example, in biomarker testing.... Show more »

Chimera Biotec is a bioanalytical Contract Research Organization (CRO) and immunoassay platform provider specialized in ultra sensitive large-molecule bioanalysis and the worlds leading Immuno-PCR (IPCR) based technology vendor. Chimera Biotec provides great alternatives in bioanalytical CRO services.

The word "chimera" originates from Greek mythology, where a hybrid creature is composed of the bodyparts of multiple animals. In analogy, the core reagents in our proprietary Imperacer® immunoassay technology are chimeric antibody-DNA conjugates. Combining the specificity of antibody-target binding with exponential signal amplification of the DNA analysis, we provide ultra sensitivity. In preclinical support or limited study sample volume our ability to limit sample requirement to few microliter while still providing single digit pg/ml sensitivities can be very helpful, for example, in biomarker testing.

Our team of dedicated scientists is committed to deliver immunoassay performance exceeding your highest expectations.

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Biomarker Assay Development
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Bioanalytical Assays
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Chimera Biotec is well aware of the critical role ultra sensitive bioanalysis plays in modern drug development of biologics, biosimilars and biobetters. It is our goal to ensure your success in all phases of drug development providing highly sensitive, accurate and reliable bioanalysis data on-time.

Your study samples will be... Show more »

Chimera Biotec is well aware of the critical role ultra sensitive bioanalysis plays in modern drug development of biologics, biosimilars and biobetters. It is our goal to ensure your success in all phases of drug development providing highly sensitive, accurate and reliable bioanalysis data on-time.

Your study samples will be stored, handled, analyzed, reported and archived with greatest care and swift turn around:

  • Ultra sensitive ligand-binding assay sample testing based on Chimera Biotec’s proprietary Imperacer® platform
  • Sample storage in monitored environment
  • Spirit of GLP or method transfer for bioanalytical sample testing support under full GLP regime according to validated SOPs
  • Sample logistics and data reconciliation services to support multi center clinical trials
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Immunoassay Development
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Our highly experienced project management and scientific team will ensure that your needs for ultra sensitive immunoassay sample testing support and regulatory guidance will make the perfect match.

Aiming for non-regulated discovery phase support, spirit-of-GLP clinical phase support or IND-enabling TOX under full GLP-regime,... Show more »

Our highly experienced project management and scientific team will ensure that your needs for ultra sensitive immunoassay sample testing support and regulatory guidance will make the perfect match.

Aiming for non-regulated discovery phase support, spirit-of-GLP clinical phase support or IND-enabling TOX under full GLP-regime, we will make sure that Imperacer® method validation is custom designed towards your expectations on bioanalytical support.

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Assay Development
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Chimera Biotec is the worlds leading provider of Immuno-PCR (IPCR) based assay development services for novel biologics and biosimilars and biomarkers; basically any kind of macromolecule analyte.

Imperacer® immunoassay development begins with in-depth consultation with your dedicated project manager, to develop the optimal... Show more »

Chimera Biotec is the worlds leading provider of Immuno-PCR (IPCR) based assay development services for novel biologics and biosimilars and biomarkers; basically any kind of macromolecule analyte.

Imperacer® immunoassay development begins with in-depth consultation with your dedicated project manager, to develop the optimal workplan for your project:

  1. Reagent Qualification: Provide us your proprietary critical reagents or support our search of suitable commercial material with your guidance
  2. Antibody-DNA conjugation: We make sure that the coupling of marker DNA to the detection reagent supports it´s functionality and binding epitopes
  3. Assay setup and optimization: We aim for highest sensitivity, suitable sample consumption and adaptation to your intended study matrix. Direct communication between you and our dedicated project managers will support us to develop the method according to your expectations.
  4. Assay parameter characterization and pre-validation: Fine-tune the method for upcoming studies in preclinics and clinics. Our dedicated project managers develp a validation protocol together with you according to your study requirements and regulatory guidelines.
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Biomarkers
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Pharmacology & Toxicology
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Experimental Design
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Bioanalysis
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Project Management, Consulting, & Support Services
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Immunoassays
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Immunoassays Services

Immunoassays Services

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