CHELONIA S.A.

Life Sciences constitute a sector that continuously grows, develops and changes. Global and local trends affect your business, and understanding the interconnections is what makes you differentiate inside a big and competitive market. Chelonia helps you design your business journey and shape your future.

Our team has a wide experience worldwide and can support you with:
- Direction of investment decisions
- Customer segmentation & targeting
- Go-to-market strategy
- Portfolio management
- Sales effectiveness
- Pricing

Advising healthcare and life science businesses on how to raise development capital, utilise investments, or finance an MBO/MBI. We work as external service provider of some of the most famous global bank. Our basket of prospective investors includes financial and strategic global players.

Polypharmacology

Polypharmacology is the design or use of pharmaceutical agents that act on multiple targets or disease pathways.

The in house database of >12K unique molecules in clinical development or on the market will be used in a combination of ligand and structure based techniques along with annotated/predicted polypharmacology. These data will be interpreted on the target disease to identifly the most promising drug of combination of drugs

Proprietary Virtual Screening tools able to screen > 1billion molecule per day can be used to in silico address selectivity among paralogue target or cross species reactivity and explore efficently the scaffold decoration pattern to design targeted and focused followup libraries to speed up the lead to candidate transition.

Based on more than > 100 validated robust chemical reactions amenable for parallel synthesis and carefull selection of building blocks according to chemical reactivity and drug likeness we have enumerated more than 300 billion drug like compounds. This Tangible Chemical Space can be used to identity uncovered chemical space in patents for analogue based strategies, identify novel scaffolds retaing the decoratin pattern for scaffold hopping, identify novel and unexplored drug like chemical space.

Based on an up-to-date database of validated onstock compounds (> 9 Million unique compounds) accoring to the clients requirements we can define the desired reference drug like chemical space and required chemical novely. On this privilaged chemical space we can tailor the library design according to different criteria (scaffold diversity based, chemical diversity based, scaffold hopping, analogue based, ...) and screenig layouts (optimize for HTS, minimize cherry peaking, ...)

State of the art ligand and structure based in silico tools will be used to perform in silico simulations for the identification of the most promising candidates for esperimental validation. We maintain curated database of small molecular weights (<= )of commercially avaiable conpounds > 30K) Druglikeness and chemical novelty of the screeened database will be tailored of customer needs and project's requirements

State of the art ligand and structure based in silico tools will be used to perform in silico simulations for the identification of the most promising candidates.

Proprietary Tools for quality control and kinetic data analysis, of the raw data, Hit Identification and efficient hit clustering and privileged scaffold.

Proprietary HPC Molecular Docking tool able to screen > 1billion molecule per day can be used to explore very large chemical space and / or address

Lead Identification and Validation Services

Compound Libraries Services

Request for Invention

We innovate on behalf of our many customers in a variety of industries, ranging from leading multinational companies to startups and regional Small & Medium Enterprises (SMEs). Chelonia cultivates working relationships with innovators worldwide through its global innovation network, representing research institutes, universities, and companies. On behalf of customer, we scout R&D platforms and IPs worldwide or we build a scientific temporary team to solve challenges and problems ranging from genetics to robotics, AI and energy.

Scientific documents sometimes contain serious errors in data, analysis or text, either because of honest mistakes or because of deliberate fraud. Combining informatics tools with the insight of our experts, we uncover potential problems for scientific publishers and journals, academic institutions, public bodies, industry. We check for:
* Improper image manipulations
* Number fabrication and manipulated statistics
* Text plagiarism

Be part of Chelonia Factory

We live in an age of incredible scientific discovery and innovation. Scientists can now sequence entire human genomes in just hours. They can turn skin cells into heart cells and can create computer chips that mimic how the brain works. Life sciences help energy industry to find out new way for producing electricity. If your goal is to pair this type of world-class science with real human impact, there is no better place in the world to be than Chelonia factory.
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Are you interested in transforming your innovative research into life sciences that impacts everyone lives? Do you need access to drug discovery capabilities and expertise to make this happen? Did you invented a synthetic biology or artificial intelligence solution to some challenge in genomics or big data management and you need help to design a roadmap ? Are you applying robotics and engineering to life sciences challenging problems. If so, working with Chelonia might be just what you need. We always look for projects with specific and testable hypotheses with the potential to deliver therapeutic benefits to patients or inventions can be really breakthrough.