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Certis Oncology Solutions, Inc.

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San Diego, California, US

About Certis Oncology Solutions, Inc.

Certis Oncology is a precision oncology and translational science company. We provide clinically relevant, predictive data that informs treatment decisions, empowers cancer patients, and reduces drug development risk. At Certis, we don’t challenge market leaders or competitors. We challenge resistance to change—a mindset willing to accept the status quo or “good enough.”
Our mission is to connect every patient to the right therapy for their cancer—the first time, every time. In the future we envision, cancer is powerless against our science.
ABOUT OUR METHODS
Our approach is rooted in a technology rapidly gaining prominence in basic research: orthotopic patient derived xenograft (O-PDX) models. By surgically engrafting a small tissue specimen of your patient’s tumor into the anatomically correct place in immunocompromised mice, we create mouse “avatars” of the patient’s cancer. The resulting O-PDX models enable simultaneous, in vivo functional assays of multiple therapeutic options in the laboratory. 
A large and expanding body of scientific literature substantiates that tumors in O-PDX models closely replicate genetic and histological characteristics of their human counterparts, making them highly predictive tools for evaluating drug response. Because disease progression is accelerated in mice, O-PDX models are especially useful in predicting resistance and response to second-line therapy–before these events are observed in the patient. To learn more, please visit certisoncology.com.

Our Services (29)


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Melanoma Patient Derived Xenograft (PDX)

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Brain Patient Derived Xenograft (PDX)

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Colorectal Patient Derived Xenograft (PDX)

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Breast Patient Derived Xenograft (PDX)

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Colon Patient Derived Xenograft (PDX)

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Sarcoma Patient Derived Xenograft (PDX)

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Lung Patient Derived Xenograft (PDX)

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Patient Derived Cancer Cell Models

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Gastric Patient Derived Xenograft (PDX)

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Cell Line Derived Xenograft (CDX) Models

Cell Line Derived Xenograft Models
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Custom Cell Model Development

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PK/PD Study Design

Pharmacokinetics/Pharmacodynamics Study Design
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Small Animal MRI

Small Animal Magnetic Resonance Imaging
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Animal Stereotactic Surgery

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Glioma Xenograft

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Stereotactic injections and MRI for intracranial imaging 


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Orthotopic Tumor Animal Models

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Certis has one of a few murine MRI machines to precisely and reproducibly measure tumor volume and metastasis over time. 


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Patient-Derived Xenograft (PDX)

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Xenograft Models

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In vivo Drug Efficacy Testing

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Data Analysis

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Oncology Animal Models

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Oncology Animal Models Services


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Animal Models of Disease

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Animal Models of Disease Services


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Animal Models and Studies

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Animal Models and Studies Services


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Biology

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Biology Services


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Human Tumor Xenograft Models

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Animal Model in vivo Analyses

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Assay Development

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Cell-Based Assays

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Omics

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