1330040431000

Center for Cancer Computational Biology (CCCB)

Boston, Massachusetts

Welcome to the Center for Cancer Computational Biology (CCCB) at the Dana-Farber Cancer Institute. The CCCB has three primary elements.

The CCCB sequencing facility offers a wide range of services to assist in the design and execution of next-generation sequencing projects. Utilizing the Illumina (Solexa) sequencing technology, we currently support a number of applications inlcuding ChIP-Seq, RNA-Seq, whole genome, whole exome, and targeted re-sequencing.

The analytical services and support platform aims to provide state-of-the-art assistance in the collection, management, analysis, and interpretation of large-scale data with a focus on data generated using 'omic technologies. In addition, we offer software, services, and training designed to assist investigators in advancing their research.

The CCCB research program is focused on development of new methods for improving analysis and... Show more »

Welcome to the Center for Cancer Computational Biology (CCCB) at the Dana-Farber Cancer Institute. The CCCB has three primary elements.

The CCCB sequencing facility offers a wide range of services to assist in the design and execution of next-generation sequencing projects. Utilizing the Illumina (Solexa) sequencing technology, we currently support a number of applications inlcuding ChIP-Seq, RNA-Seq, whole genome, whole exome, and targeted re-sequencing.

The analytical services and support platform aims to provide state-of-the-art assistance in the collection, management, analysis, and interpretation of large-scale data with a focus on data generated using 'omic technologies. In addition, we offer software, services, and training designed to assist investigators in advancing their research.

The CCCB research program is focused on development of new methods for improving analysis and interpretation of genomic data through integration of diverse data types with the goal of creating open-source software tools to be made freely-available to the research community.

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    Bioinformatics
    Price on request
    Please contact Center for Cancer Computational Biology (CCCB) for more information regarding this service.
    Chromatin immunoprecipitation (ChIP) data analysis
    Price on request
    Please contact Center for Cancer Computational Biology (CCCB) for more information regarding this service.
    Data storage
    Price on request
    Please contact Center for Cancer Computational Biology (CCCB) for more information regarding this service.
    Illumina NGS
    Illumina next generation sequencing
    $1,200.00 USD
    per Sample

    Single end 50 cycle $1,200
    Single end 100 cycle $1,600
    Paired-end 50 cycle $2,000
    Paired-end 100 cycle $2,700

    Additional Sample QC Cost per additional sample/library - $50

    Single end 50 cycle $1,200
    Single end 100 cycle $1,600
    Paired-end 50 cycle $2,000
    Paired-end 100 cycle $2,700

    Additional Sample QC Cost per additional sample/library - $50

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    Illumina library generation for next generation sequencing
    $1,015.00 USD
    per Sample

    ChIP-Seq Library Prep – Reagents $230 per sample
    ChIP-Seq Library Prep – Labor $960 per 10 samples
    Required input: 10ng DNA minimum

    RNA-Seq Poly-A Prep – Reagents $70 per sample
    RNA-Seq Poly-A Prep – Labor $1,080 per 10 samples
    Required input: 100ng total RNA minimum

    RNA-Seq DSN Prep – Reagents... Show more »

    ChIP-Seq Library Prep – Reagents $230 per sample
    ChIP-Seq Library Prep – Labor $960 per 10 samples
    Required input: 10ng DNA minimum

    RNA-Seq Poly-A Prep – Reagents $70 per sample
    RNA-Seq Poly-A Prep – Labor $1,080 per 10 samples
    Required input: 100ng total RNA minimum

    RNA-Seq DSN Prep – Reagents $135 per sample
    DNA - Fragment Library Prep – Labor $1,200 per 10 samples
    Required input: 100ng total RNA minimum

    DNA - Fragment Library Prep – Reagents $55 per sample
    DNA - Fragment Library Prep – Labor $960 per 10 samples
    Required input: 1ug DNA minimum

    DNA - Mate-Pair Prep – Reagents $380 per sample
    DNA - Fragment Library Prep – Labor $1,920 per 10 samples Required input: 10ug DNA minimum

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    Metagenomics data analysis
    Price on request

    We offer a analytical services for genomic and other ‘omic data including: gene expression, copy number variation, ChIP-chip/ChIP-seq, SNP, and next generation DNA sequencing data.

    Some examples of the type of questions we can work with investigators to answer are as follows:

    Identify novel gene signatures, and... Show more »

    We offer a analytical services for genomic and other ‘omic data including: gene expression, copy number variation, ChIP-chip/ChIP-seq, SNP, and next generation DNA sequencing data.

    Some examples of the type of questions we can work with investigators to answer are as follows:

    Identify novel gene signatures, and validate them using our large in-house cancer gene expression profile database.

    Discover which biological pathways are differentially expressed.

    Identify pattern of chromosomal abnormalities and loss of heterogeneity in aCGH data from SNP arrays.

    Discover promoters or regulators of gene expression.

    Build network models of gene expression, protein-protein interaction and literature data to uncover new biological connections.

    Integration of high-dimensional clinical and demographic information with ‘omic data.

    Multi-platform analysis e.g. Affymetrix, Illumina, and DASL data.

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    NGS data analysis
    Next generation sequencing data analysis
    Price on request
    Please contact Center for Cancer Computational Biology (CCCB) for more information regarding this service.
    SNP genotyping data analysis
    Price on request
    Please contact Center for Cancer Computational Biology (CCCB) for more information regarding this service.
    Single cell gene expression analysis
    Price on request
    Please contact Center for Cancer Computational Biology (CCCB) for more information regarding this service.
    Software development
    Price on request
    Please contact Center for Cancer Computational Biology (CCCB) for more information regarding this service.

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