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Censo Biotechnologies

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Roslin, GB

About Censo Biotechnologies

Censo is a leader in the creation of induced Pluripotent Stem Cells (iPSCs) and their transformation to specific cell types for use in drug discovery. Our clients include leading pharmaceutical companies and others involved in drug discovery who recognise that iPSC technology offers a wholly new method for... Show more »

Censo is a leader in the creation of induced Pluripotent Stem Cells (iPSCs) and their transformation to specific cell types for use in drug discovery. Our clients include leading pharmaceutical companies and others involved in drug discovery who recognise that iPSC technology offers a wholly new method for testing drugs with human cells from both specific individuals and large cohorts.

We provide a full spectrum of services from creating iPSCs to drug screening, including:

  • Human tissue sample procurement
  • iPSC generation
  • iPSC genome editing
  • Differentiated cell protocol development and industrialisation
  • Production of differentiated cells of specific lineages
  • Cell based assay development
  • Compound screening

We support our clients drug discovery by providing iPSCs and contract research services.

The company was founded in 2016, through the merger of Roslin Cellab and Roslin Cell Sciences, and has facilities in both Edinburgh and Cambridge, UK.

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Our Services (34)


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Induced Pluripotent Stem Cell (iPSC) Differentiation

Price on request

We develop iPSC differentiation protocols focussed on compound screening applications. As well as generating physiologically relevant cell types, we ensure our differentiation protocols address the challenges of cost, scale, repeatability, and robustness. Most importantly, we ensure that our protocols are optimised to create cells... Show more »

We develop iPSC differentiation protocols focussed on compound screening applications. As well as generating physiologically relevant cell types, we ensure our differentiation protocols address the challenges of cost, scale, repeatability, and robustness. Most importantly, we ensure that our protocols are optimised to create cells ready for use in relevant assay platforms and can tailor these to your specific needs..

All protocols are stress tested to ensure they are consist using a single cell line multiple times and also work robustly with multiple cell lines, from both healthy and disease backgrounds. Protocols are fully documented in Standard Operating Procedures and used by multiple researchers before being assessed as robust.

Often starting with protocols developed in academic research, we have “industrialised” protocols for the differentiation of many cell lineages. Our current client collaborations focus on the generation of:

  • Tissue Resident Macrophage and Microglia
  • Sensory neurons
  • Cortical neurons

Please get in touch to find out more about our capacity to produce these cell types or our ability to develop and refine other differentiation protocols specific to your needs.

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Induced Pluripotent Stem Cell (iPSC) Generation

Price on request

Our dedicated pluripotent cell scientists are experts in the generation and cultivation of induced pluripotent stem cells (iPSCs)

Furthermore, our in-house genome editing team have specific experience in the creation of high value genetically modified pluripotent stem cell lines and work seamlessly with our cell production and... Show more »

Our dedicated pluripotent cell scientists are experts in the generation and cultivation of induced pluripotent stem cells (iPSCs)

Furthermore, our in-house genome editing team have specific experience in the creation of high value genetically modified pluripotent stem cell lines and work seamlessly with our cell production and quality control teams.

Censo provides all aspects of pluripotent cell culture services including:

  • iPSC generation
  • Genome editing
  • iPSC line expansion and banking
  • iPSC line characterisation and safety testing
  • Custom product testing with pluripotent cells
  • Cryo-storage and distribution
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Induced Pluripotent Stem Cell (iPSC) Genome Editing

Price on request

Our dedicated pluripotent cell scientists are experts in the generation and cultivation of induced pluripotent stem cells (iPSCs)

Furthermore, our in-house genome editing team have specific experience in the creation of high value genetically modified pluripotent stem cell lines and work seamlessly with our cell production and... Show more »

Our dedicated pluripotent cell scientists are experts in the generation and cultivation of induced pluripotent stem cells (iPSCs)

Furthermore, our in-house genome editing team have specific experience in the creation of high value genetically modified pluripotent stem cell lines and work seamlessly with our cell production and quality control teams.

Censo provides all aspects of pluripotent cell culture services including:

  • iPSC generation
  • Genome editing
  • iPSC line expansion and banking
  • iPSC line characterisation and safety testing
  • Custom product testing with pluripotent cells
  • Cryo-storage and distribution
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Human Tissue Procurement

Price on request

At Censo, we support the development of new treatments for disease by creating iPSC lines from tissue samples procured from individuals with relevant genotypic or clinical backgrounds.

Using our capacity to generate large numbers of iPSC lines, we can create lines from individuals with a diverse variety of genetic backgrounds... Show more »

At Censo, we support the development of new treatments for disease by creating iPSC lines from tissue samples procured from individuals with relevant genotypic or clinical backgrounds.

Using our capacity to generate large numbers of iPSC lines, we can create lines from individuals with a diverse variety of genetic backgrounds and varying clinical histories. By doing so, we provide researchers with powerful resources to investigate variations in disease phenotype and variations in drug efficacy across the population as a whole.

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Assay Development

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For differentiated disease relevant human iPSCs to provide new approaches to drug development, it is essential that they can be used in relevant phenotypic assays suitable for compound screening.

Our assay development and compound screening resource is based at our Cambridge facility, and led by ex-pharma scientists with... Show more »

For differentiated disease relevant human iPSCs to provide new approaches to drug development, it is essential that they can be used in relevant phenotypic assays suitable for compound screening.

Our assay development and compound screening resource is based at our Cambridge facility, and led by ex-pharma scientists with extensive experience of cell based compound screening. Working seamlessly with our iPSC production, gene editing and cell differentiation resources, our assay development and compound screening teams offer a fully integrated service to clients who wish to be at the forefront of iPSC based drug discovery.

Using our human iPSC derived cells from healthy and specific disease populations we can custom build and validate iPSC-based cell models at scale to provide new insights and functional disease relevant understanding of our clients leads and drug candidates:

  • Wide range of endpoint detection systems available
  • Advice on best approaches to compound evaluation
  • Custom phenotypic assay development
  • Assay and target validation
  • Disease relevant compound characterisation

Our technology also enables the study of genotype-phenotype relationships in large populations, providing an understanding of patient population therapeutic response variability.

Our assay platform capabilities include:

  • Hamamatsu FDSS for compound activity on Calcium flux.
  • ThermoFisherArray Scan VTI for high-content imaging e.g. phagocytosis, neurite outgrowth.
  • Agilent Seahorse for energy metabolism e.g. mitochondrial function assessment.
  • Bio-tekSynergyHT for luminescent, fluorescent and absorbance plate based assays e.g. cytokine release, intracellular signaling readouts.
  • Guava easycyteHT for flow cytometry to measure surface marker expression
  • Li-COR odyssey for western blot quantification
  • Quant studio 7 for qPCR analysis

We can also offer electrophysiology, electrical field stimulation and MEA through collaborator network.

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Compound Profiling

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ZFN-Mediated Genome Editing

Zinc Finger Nuclease-Mediated Genome Editing
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3D Cell Culture Models

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CRISPR Modified Cell Lines

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Cell Co-Cultivation

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Stem Cell Differentiation

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Cell Line Generation

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Testing of Cell Lines

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Primary Cell Culture

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Tissue Processing

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Drug Discovery & Development

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Drug Discovery & Development Services

Drug Discovery & Development Services

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Drug Discovery

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Drug Discovery Services

Drug Discovery Services

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Lead Identification and Validation

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Lead Identification and Validation Services

Lead Identification and Validation Services

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Biology

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Biology Services

Biology Services

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Cells and Tissues

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Cells and Tissues Services

Cells and Tissues Services

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Biospecimens

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Biospecimens Services

Biospecimens Services

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Human Biospecimens

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Human Biospecimens Services

Human Biospecimens Services

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Human Tissue

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Human Tissue Services

Human Tissue Services

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Genetic Engineering

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Genetic Engineering Services

Genetic Engineering Services

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Cell and Tissue Culture

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Cell and Tissue Culture Services

Cell and Tissue Culture Services

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Mammalian Cell Culture

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Mammalian Cell Culture Services

Mammalian Cell Culture Services

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Induced Pluripotent Stem Cell (iPSC) Culture

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Embryonic Stem Cell (ESC) Culture

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Pluripotency Analysis

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Embryonic Stem Cell Culture Training

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Embryoid Body Formation

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Live Cell Assay Development

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Cell-Based Assays

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Cell Lines

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Kevin Bruce

Chief Operating Officer
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Simon MacKenzie

Chief Business Officer
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Suzy Purcell

Financial Controller

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