1347928375000

Cardiovascular Physiology Core Facility

Madison, Wisconsin, US

The Cardiovascular Physiology Core Facility provides University of Wisconsin (UW) and non-UW researchers with a central resource for creating and studying animal models of disease on a fee-for-service basis.

While the central focus of the facility is cardiovascular research, the techniques employed are often useful to investigators in other fields. Currently, the facility is conducting studies into diabetes, bone growth, drug toxicology, and gene therapy in liver and skeletal muscle, as well as cardiovascular disease. One of the most popular services provided by the facility is evaluation of the cardiovascular phenotype of transgenic mice.

Cardiovascular Physiology Core Facility has not listed any services.

Pulmonary Hypertension Animal Models
Price on request
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Animal Echocardiography
Price on request

Complete echocardiogram including B-mode, M-mode, aortic artery, pulmonary artery and mitral velocity. Additional services are available.

Pricing:
Mouse or Rat
• Echocardiography (2-D, M-mode, Doppler flows, TDI, and complete analysis) $120/animal

Pigs
• Echocardiography (available upon request)

Complete echocardiogram including B-mode, M-mode, aortic artery, pulmonary artery and mitral velocity. Additional services are available.

Pricing:
Mouse or Rat
• Echocardiography (2-D, M-mode, Doppler flows, TDI, and complete analysis) $120/animal

Pigs
• Echocardiography (available upon request)

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Animal Surgery
Price on request

Pressure overload
• Aortic banding
• Pulmonary artery banding
Myocardial infarction
Ischemia, Ischemia reperfusion
Hindlimb Ischemia
Vascular catheterization
Stem Cell Injections

Pressure overload
• Aortic banding
• Pulmonary artery banding
Myocardial infarction
Ischemia, Ischemia reperfusion
Hindlimb Ischemia
Vascular catheterization
Stem Cell Injections

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Custom Cardiovascular Animal Models
Price on request

Mice, rats and guinea pigs:
• Cardiovascular phenotype of transgenic animals
• Surgical models of chronic myocardial infarction, ischemia and reperfusion, heart failure and cardiac hypertrophy
• Echocardiographic and Doppler imaging
• Evaluation of cardiac mechanisms and function through non-invasive techniques
○... Show more »

Mice, rats and guinea pigs:
• Cardiovascular phenotype of transgenic animals
• Surgical models of chronic myocardial infarction, ischemia and reperfusion, heart failure and cardiac hypertrophy
• Echocardiographic and Doppler imaging
• Evaluation of cardiac mechanisms and function through non-invasive techniques
○ Echocardiographic and Doppler imaging
○ Assistance with other imaging including microPT, CT and MRI
• Ambulatory blood pressure and ECG recordings (telemetry) arrhythmias
• Exercise tolerance testing and exercise training
• Invasive hemodynamic measurements
○ Right and left heart Pressure-Volume analysis
○ Cardiac contractility, Cardiac output, ejection fraction, dp/dt, tau
○ RV, LV and aortic blood pressure
• Hindlimb ischemia model
• Assistance with drug studies, tissue collection, blood collection.


Dogs, pigs and non-human primates:
• Acute, open-chest or closed chest porcine models of myocardial ischemia, infarction and stunning
• Acute open- and closed-chest canine and porcine preparations for investigating coronary blood flow, myocardial metabolism and arrhythmias
• Chronic canine and porcine models of myocardial ischemia, stunning, hibernation and heart failure
• Complete echocardiographic and Doppler imaging
• Invasive hemodynamic measurements
○ Pulmonary wedge pressures, central venous oxygen saturation cardiac output, ejection fraction, Dp/dt, tau.
• X-ray guided catheters and myocardial injections
• Assistance with all non-invasive imaging (PET, MRI CT, Ultrasound)


Pricing:

Mouse or Rat
• Echocardiography (2-D, M-mode, Doppler flows, TDI, and complete analysis) $120/animal
• Chronic ECG or arterial blood pressure implantation and data analysis $250/animal
• Left ventricular Pressure: Volume loop measurement and data analysis $225/animal
• Pulmonary artery pressure measurement and analysis $125/animal
• Mouse maximal exercise capacity (treadmill familiarization and 3 max. tests) $100/animal
• Drug induced myocardial hypertrophy $75/animal
• Myocardial infarct $120/animal
• Aortic banding model of LV hypertrophy $100/animal


Pigs
Angiography (available upon request)
Pet scanning (available upon request)
MRI (available upon request)
Ameriod constrictors (available upon request)
Ischemia/reperfusion (available upon request)
Chronic procedures (available upon request)
Echocardiography (available upon request)
Gene therapy delivery (available upon request)


Dogs
Tachycardia pace heart failure $1,500/animal

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Animal Electrocardiography
Price on request

Mouse or Rat
• Echocardiography (2-D, M-mode, Doppler flows, TDI, and complete analysis) $120/animal

Pigs
• Echocardiography (available upon request)

Mouse or Rat
• Echocardiography (2-D, M-mode, Doppler flows, TDI, and complete analysis) $120/animal

Pigs
• Echocardiography (available upon request)

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Animal Exercise Testing
Price on request

Mouse maximal exercise capacity (treadmill familiarization and 3 max. tests)

Mouse maximal exercise capacity (treadmill familiarization and 3 max. tests)

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Animal Sonomicrometry
Price on request
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Animal Models and Studies
Price on request
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Respiratory Disease Animal Models
Price on request

Respiratory Disease Animal Models Services

Respiratory Disease Animal Models Services

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Animal Model in vivo Analyses
Price on request
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Animal Models of Disease
Price on request
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Cardiovascular Animal Models
Price on request
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Animal Physiology Analyses
Price on request
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Animal Cognition & Behavior Tests
Price on request
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Animal Motor Function Tests
Price on request
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Animal Imaging
Price on request
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November 19, 2014

Positive review received for Animal Exercise Testing:

"The Cardiovascular Physiology Core Facility was detail oriented, punctual and great to work with. I would highly recommend this lab."

October 27, 2014

Positive review received for Custom Cardiovascular Animal Models:

"I would highly recommend the Cardiovascular Physiology Core Facility. Jill and her team were able to contribute greatly to my project and the results were very well documented and presented. I would definitely work with Jill and her team again."

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