BrainXell, Inc.
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Madison, Wisconsin, US
BrainXell provides iPSC-derived human neurons to the pharmaceutical industry and other research organizations for CNS drug discovery and development. Utilizing proprietary technology developed over the last two decades by Professor Su-Chun Zhang at the University of Wisconsin-Madison, we generate high-purity, subtype-specific neurons that rapidly mature. Multiple neuron subtypes relevant to a range of disorders are available. Additionally, any of these neurons can be made in custom batches from 50 million to 10 billion neurons from iPSC or ESC lines selected by the customer.
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Have an iPSC or ESC line relevant to a specific disorder? BrainXell provides custom services to produce neurons from customer-supplied iPSC cell lines. We accelerate your research by rapidly producing desired neuronal subtypes of high purity that can be the basis of a dependable experimental system.
Subtype options include: Motor Neurons, Glutamatergic Neurons, GABAergic Neurons, Mixed Cortical Neurons, Dopaminergic Neurons, Serotonergic Neurons, and Astrocytes.
Flexible production scales available: 50 million to 10 billion neurons.
| Neuron Type | Neuronal Subtype Purity | Time to Use | Catalog Number |
|---|---|---|---|
| Spinal Motor Neurons | >70% | 5 - 10 days | BX-0100 |
| Midbrain Dopaminergic Neurons | >50% | 10 - 14 days | BX-0200 |
| Glutamatergic Neurons | >70% | 7 - 12 days | BX-0300 |
| GABAergic Neurons | >70% | 7-12 days | BX-0400 |
| Mixed Cortical Neurons | >90% | 7 - 12 days | BX-0500 |
| PV-Enriched GABAergic Neurons | >15%/>70% | 7-12 days | BX-0450 |
| Medium Spiny GABAergic Neurons | >70% | 7-12 days | BX-0700 |
| Serotonergic Neurons | >70% | 7-12 days | BX-0800 |
BrainFast Neuronal Maturation Supplement
BrainXell’s BrainFast Neuronal Maturation Supplement is a proprietary combination of small molecules that is used to accelerate the differentiation of neural progenitor cells to mature neurons. It is effective with a variety of neuronal subtypes including, but not limited to, motor neurons, glutamatergic neurons, and GABAergic neurons.
A range of fluorescence microscopy and plate reader based assays can be incorporated in custom projects to examine viability, toxicity, marker expression and more. Please inquire for assay and model specifics.
Custom production of neurons to fit your research goals.
Have an iPSC or ESC line relevant to a specific disorder? BrainXell provides custom services to produce neurons from customer-supplied iPSC cell lines and perform in-house neuronal assays. We accelerate your research by rapidly producing desired neuronal subtypes of high purity that can be the basis of a dependable experimental system.
Subtype options include: Motor Neurons, Glutamatergic Neurons, GABAergic Neurons, Mixed Cortical Neurons, Dopaminergic Neurons, Serotonergic Neurons, and Astrocytes.
Flexible production scales available: 50 million to 10 billion neurons
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