BioTools, Inc. is the world’s leading provider of instrumentation and services for structure determination for chiral and biological molecules.
Our ground-breaking techniques for chiral characterization consist of vibrational circular dichroism (VCD) for absolute configuration (AC) and Molecular Rotational Resonance (MRR) spectroscopy for diastereomer and impurity anlyses . VCD analysis is fast, non-destructive and requires no crystallization or chromophore derivatization for AC. MRR can identify and quantify all components in a complex mixture including diastereomers.
For biologics, we use Raman, Raman Optical Activity (ROA) and FTIR for Higher Order Structure (HOS) and comparability studies.
Determination of absolute configuration of chiral molecules in solution - without the need to grow a crystal or crystallography
Comparability, stability, secondary structure, higher order structure
Infrared spectroscopy services Services
Identify and quantify components in a mixture without the need for standards, calibration models, chemometrics or chromatography (separation). Replaces NMR & GC-MS. Can be done on-line, at-line or off-line.
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