BioTools, Inc. is the world’s leading provider of instrumentation and services for structure determination for chiral and biological molecules.
For chiral molecules we specialize in determination of absolute configuration (AC) with our ground-breaking technique of vibrational circular dichroism (VCD). VCD analysis is performed in solution; it is fast, non-destructive and requires no crystallization or chromophore derivatization for AC.
For biologics (including peptides, proteins and conjugates) and other bio-based pharmaceuticals such as Saccharide-derived, nucleic acid-based, complex drugs, and conjugates, we use Raman, Raman Optical Activity (ROA) and FTIR for Higher Order Structure (HOS) and comparability studies.
Other molecules tested include cryopreservation media, cell culture media, protein-based food and supplements.
Our approach is to help you find a solution to your problem - so please ask us if we can help!
Determination of absolute configuration of chiral molecules in solution - without the need to grow a crystal or crystallography
Comparability, stability, secondary structure, higher order structure
Infrared spectroscopy services Services
Identify and quantify components in a mixture without the need for standards, calibration models, chemometrics or chromatography (separation). Replaces NMR & GC-MS. Can be done on-line, at-line or off-line.
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