Qipvnoshr22etadjlhke biorxn logo white

BioRxn, LLC

ic No Reviews Yet
ic No Completed Orders
Chapel Hill, North Carolina, US

About BioRxn, LLC

BioRxn, LLC is a CRO that performs metabolomic analyses on biofluids and tissue extracts, and performs 2D and 3D cultures with flux analysis using 13C-labeled nutrients or xenobiotics added to culture mediums.

Our technology is a fluidized-bed bioreactor that combines alginate-encapsulation with... Show more »

BioRxn, LLC is a CRO that performs metabolomic analyses on biofluids and tissue extracts, and performs 2D and 3D cultures with flux analysis using 13C-labeled nutrients or xenobiotics added to culture mediums.

Our technology is a fluidized-bed bioreactor that combines alginate-encapsulation with fluidized-bed bioreactor to achieve the world’s densest liver cultures. With diameters of ~400 μm, the alginate-encapsulated tissues mimic the liver to achieve near-in vivo nutrient and oxygen gradients. These preparations can be maintained for months while preserving their Type 1 and Type 2 drug metabolizing functions.

Near tissue density permits physiological concentrations of paracrine factors to accumulate in media, and in conjunction with 31P and 13C NMR can be used to derive physiologically-relevant pharmacokinetic parameters.

Show less

Our Services (7)


ic

3D Cell Culture Models

Price on request
Request a quote for more information about this service.

ic

2D Cell Culture

Price on request
Request a quote for more information about this service.

ic

Mammalian Cell Culture

Price on request
Request a quote for more information about this service.

ic

Omics

Price on request
Request a quote for more information about this service.

ic

Metabolomics

Price on request
Request a quote for more information about this service.

ic

Cells and Tissues

Price on request
Request a quote for more information about this service.

ic

Biology

Price on request
Request a quote for more information about this service.

Not finding what you're looking for?

Get info on this provider's capabilities without requesting a quote.
Missing Avatar

Jeffrey Macdonald

President
FileType/PDF Created with Sketch.

Johnson_MRM2012.pdf

FileType/PDF Created with Sketch.

Keshari_2016.pdf

FileType/PDF Created with Sketch.

Lee_Chap13.pdf

FileType/PDF Created with Sketch.

Macdonald_Fluxomics_CMB_2013.pdf

FileType/PDF Created with Sketch.

TikunovEtAl_2017.pdf

FileType/PDF Created with Sketch.

Winnike_Metabolomics2012.pdf

BioRxn, LLC has not received any reviews.

BioRxn, LLC has not received any endorsements.