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Bioqual, Inc.

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Rockville, MARYLAND, US

About Bioqual, Inc.

BIOQUAL was established in 1981, and performs contract research services focused on in vivo models of human diseases including AIDS, influenza, RSV infection, Flavivirus infections including Zika and Dengue, malaria, hepatitis, and cancer. BIOQUAL has laboratories and vivariums under both BSL-2 and BSL-3... Show more »

BIOQUAL was established in 1981, and performs contract research services focused on in vivo models of human diseases including AIDS, influenza, RSV infection, Flavivirus infections including Zika and Dengue, malaria, hepatitis, and cancer. BIOQUAL has laboratories and vivariums under both BSL-2 and BSL-3 containment. In addition, BIOQUAL maintains CDC-approved BSL-3 containment laboratories for studies associated with Select Agents including highly pathogenic avian influenza.

BIOQUAL currently employs 160 personnel. Facilities: BIOQUAL, Inc. (Rockville, Maryland) has over 90,000 sq ft of dedicated BSL-2+ laboratory animal space and over 7,000 sq ft of laboratory space. Currently the laboratories are involved with SIV/SHIV and other viral disease of humans. Laboratories outfitted for molecular biology, special procedures and instrumentation are shared with other groups within the company. All laboratories are equipped with Class II, Type B laminar flow hoods, low speed centrifuges, dual chamber tissue culture incubators and refrigerator/freezers. Care and husbandry of all research animals will be provided in compliance with US federal laws and guidelines as well as in accordance with recommendations provided in the NIH guide and other accepted standards of laboratory animal care and use.

BIOQUAL’s laboratories are actively involved in the evaluation of vaccines, vaccine therapeutics, microbicides, and drug therapies. In vitro services are available for evaluation of immunologic, virologic, and molecular parameters. These services include sample processing, virus stock generation, quantitation of infectious virus, virus neutralization assays, hemagglutination inhibition assay, quantitative PCR, antigen and antibody ELISA detection assays, flow cytometry, lymphocyte proliferation, and other cell-based assays.

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Certifications & Qualifications

BSL-2 BSL-3 BSL-4

Our Services (52)


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Zika Virus Animal Models

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Mouse Non-human primates (NHP)

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HIV Animal Models

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Mouse Non-human primates (NHP)

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RSV Animal Models

Respiratory Syncytial Virus Animal Models
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Non-human primates (NHP)

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Viral Infection Animal Models

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Mouse Non-human primates (NHP)

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Malaria Animal Models

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Non-human primates (NHP)

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Influenza Animal Models

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Ferret Mouse Non-human primates (NHP)

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Infectious Disease Animal Models

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Select Agent models - pox virus, avian influenza, others as requested

Select Agent models - pox virus, avian influenza, others as requested

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RNA Extraction and Purification

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Genomic DNA Extraction

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Viral Vector Purification

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DNA Sequencing

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PCR

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qPCR

Quantitative PCR
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Virus Characterization

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Biochemistry & Molecular Biology

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Cell Cycle Analysis

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Cytokine Analysis

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Quantitation of cytokines and cytokine receptors

Quantitation of cytokines and cytokine receptors

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ELISpot Assays

Enzyme-Linked ImmunoSpot Assays
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ELISpot assays for macaque cytokines

ELISpot assays for macaque cytokines

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Immunostaining

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By ELISA or Western Blots

By ELISA or Western Blots

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Antigen Detection by Enzyme Immunoassay

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By ELISA or Western Blots

By ELISA or Western Blots

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T Cell Activation and Proliferation Assays

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Thymidine uptake or CFSE

Thymidine uptake or CFSE

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Flow Cytometry

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Mammalian Cell Culture

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Cytometry

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Immunoassays

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Cells and Tissues

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Protein Quantification

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Antibody Services

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Pharmacology & Toxicology

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Functional & Cell Type Specific Assays

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Biology

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DNA Extraction and Purification

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Clinical Chemistry

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Plasmids and Vectors

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Clinical Research

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Viral Assays

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Clinical Laboratory Services

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RNA Services

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In vitro Fertilization Models

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Pregnancy Animal Models

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In vitro Disease Models

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DNA Services

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Immune Cell Assays

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Antibody/Antigen Detection Based Testing

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Animal Models and Studies

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Nucleic Acid Services

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Protein Services

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Reproductive System Animal Models

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Microbiology

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Virology Services

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Animal Models of Disease

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Cell-Based Assays

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