BioIVT, formerly BioreclamationIVT

Organotypic 3D Lung Model

Organotypic 3D Lung Model

Animal Biologicals

Animal matrices are collected at facilities located in the United States, using BioreclamationIVT Standard Operating Procedures. This allows us to customize every order according to your exact specifications, while maintaining the highest level of product quality.

BioreclamationIVT can collect samples that meet your study requirements and protocol. Inclusion and/or exclusion criteria can be specified.

Customization

• Lot Specifications
  
  • BioreclamationIVT can provide matrices from individual animals, pooled lots or large pools. The number of animals in each pool can also be specified.
    
• Aliquoting
  
  • BioreclamationIVT can aliquot all matrices into any volume or vial size.
    
• Filtration
  
  • A standard .2u filtration is offered for all products. Additional membrane sizes are also available.
    
• Anticoagulants / Vacutainers
  
  • Both blood and plasma samples can be collected with the anticoagulant of your choice and the use of specific vacutainers can be requested.
    
• Gender
  
  • BioreclamationIVT can provide gender specific samples.
    
• Processing/Labeling
  
  • Customized processing at the time of collection is available. Barcoded labels can also be customized and include client provided ID numbers.
    
• Validation and Reserve Lots
  
  • BioreclamationIVT can provide representative samples from pools or individual animals while holding additional volume on reserve.
    
• Matched Sets
  
  • BioreclamationIVT can collect multiple matrices or anticoagulant types from a single animal.
    
• Longitudinal Studies
  
  • BioreclamationIVT can collect samples from the same animal at multiple time points. Animals can be reserved for extended use for specific studies.
    

Custom Cells

• Custom preparations of whole tissue or bone extraction (animal only)

Human Biologicals

Normal human matrices are collected from consented donors under IRB approved protocols at facilities located in the United States, using BioreclamationIVT Standard Operating Procedures. This allows us to customize every order according to your exact specifications, while maintaining the highest level of product quality.

BioreclamationIVT can collect samples that meet your study requirements. Inclusion and/or exclusion criteria can be specified such as: age, gender, weight, ethnicity, smoking status, etc. Specific questions can also be added to the case report form for further screening.

BioreclamationIVT provides viral negative normal human samples as noted on the Certificate of Analysis included with each shipment. Samples are tested in accordance with FDA regulations and found negative for HBsAG, HIV 1/2 Ab, HCV Ab, HIV-1 RNA, HCV RNA and STS.

Customization

• Lot Specifications
  
  • BioreclamationIVT can provide matrices from individual donors, pooled lots or large pools. The number of individuals in each pool can also be specified.
    
• Aliquoting
  
  • BioreclamationIVT can aliquot all matrices into any volume or vial size.
    
• Filtration
  
  • A standard .2u filtration is offered for all products. Additional membrane sizes are also available.
    
• Anticoagulants / Vacutainers
  
  • Both blood and plasma samples can be collected with the anticoagulant of your choice and the use of specific vacutainers can be requested.
    
• Gender
  
  • BioreclamationIVT can provide gender specific samples.
    
• Processing/Labeling
  
  • Customized processing at the time of collection is available. Barcoded labels can also be customized and include client provided ID numbers.
    
• Validation and Reserve Lots
  
  • BioreclamationIVT can provide representative samples from pools or individual donors while holding additional volume on reserve.
    
• Matched Sets
  
  • BioreclamationIVT can collect multiple matrices or anticoagulant types from a single donor.
    
• Longitudinal Studies
  
  • BioreclamationIVT can collect samples from the same donor at multiple time points.
    

• LiverPool 10-Donor cryoplateable human hepatocytes
  
• LiverPool 5D, 10D, 20D, 50-Donor cryosuspension human hepatocytes
  
• Animal cryoplateable and cryosuspension hepatocytes
  
• Custom hepatocyte preparations from customer supplied animals
  
• Fresh Human & Animal Hepatocytes Available.
  

• Subcellular fractions from a variety of organs, tissues, and cell lines (as available)
  
• Homogenate, S9, cytosol, microsomes, mitochondria
  
• Human & Animal

Primary cell cultures from many different tissues and/or species
- Hepatocytes
- Human Renal Proximal Tubule Cells, Glomerural Cells
- Non-parenchymal cells
- PBMCs
- Bronchial Epithelial Cells

• Adherent or suspension animal hepatocyte cultures on customer-specified dates
  
• Sprague-Dawley Rat, Beagle Dog, Cynomolgus Monkey, ICR/CD-1 Mouse

• InVitroGRO™ hepatocyte medium
  
• DMEM
  
• Ham’s F-10
  
• RPMI
  
• BSA
  
• FBS
  
• Human AB Serum
  
• Antibiotics, Supplements
  
• Stem Cell Medium
  

• InVitroCYP Human Liver Microsomes - 50Donor - average metabolism activity
  
• InVitroCYP Human Liver Microsomes - 10Donor - high metabolism activity for IC50 studies
  
• Animal Microsomes: Sprague-Dawley Rat, Beagle Dog, Cynomolgus Monkey, ICR/CD-1 Mouse
  
• Custom preparations using customer supplied animals
  
• Genotyped human liver microsomes for various CYPs (2C9, 2C19)

• RNA extraction from normal and disease state tissues
  
• RNA extraction from primary cells

• DNA extraction from normal and disease state tissues
  
• DNA extraction from primary cells

Human Tissue Services

Cell and Tissue Culture Services