BioInfoRx provides innovative cloud-based solutions for scientific information management and data analysis. Our web-based systems include powerful tools to manage general laboratory information, automate scientific process, and process biological data with bioinformatic or biostatistical methods.
Genomic Analysis Services
At BioInfoRx, we help scientists obtain biological insights from complex genomic data. We provide complete NGS analytic solutions including standard analysis of raw data, integration between multiple experiments, and online database for data mining and visualizations. We use best-practice open source tools to analyze your raw NGS data, and provide meaningful annotations and downstream data mining tools to help you infer functional insights.
As demonstrated by the numerous publications using our services or web-bases tools, our biology-centric approach has proven effective to decipher molecular mechanisms from genomic data.
Custom Scientific Information Systems
BioInfoRx provides custom-made, web-based solutions to meet special information management and data analysis needs from research labs in academia and industry. Based on BioInfoRx proprietary technology, BxAF™, we have built numerous advanced data management and processing systems for individual labs, core facilities, small biotech businesses, and large pharmaceutical companies.
Finally you can unleash the full potential of your ChIP-Seq data in a quick and easy way. With the biologist-friendly web interface powered by BxChIPSeq 2.0, you can focus on the biology without worrying about hardware, software, algorithms. Best of all, all the powerful analysis results are available to view in a browser, simple to understand and there is no steep learning curve.
Introducing BxChIPSeq 2.0: Analyzing ChIP-Seq Results Has Never Been This Easy!
Finally you can unleash the full potential of your ChIP-Seq data in a quick and easy way. With the biologist-friendly web interface powered by BxChIPSeq 2.0, you can focus on the biology without worrying about hardware, software, algorithms. Best of all, all the powerful analysis results are simple to use and there is no steep learning curve.
What is BxChIPSeq 2.0
You have spent lots of time to figure out the right conditions and antibody for chromatin immunoprecipitation, and you have paid precious grant money for the sequencing run. What's next? Your ChIP-Seq data contain rich biological information, but you are only looking at the tip of the iceberg if all you have is an Excel spreadsheet listing peaks with some annotations. You can do a lot more, including:
With BxChIPSeq 2.0, all you need to do is to send us your raw sequence data, and within a week you will have access to all the analysis mentioned above for your data in a secure website. You can log into your webpage anytime from anywhere, and you can share the results with your team members and collaborators by giving them access to your webpage.
And this convenient service is very affordable, about 10% of what you have already spent on running ChIP experiments and generating sequencing data. With this small investment, you can delve into deeper layers of your data, and easily get 5x or 10X more biological insights from your ChIP-Seq experiments.
We offer a variety of custom genomic analysis services. Our team has both strong biological and computational background, and we can tackle any questions for you.
-Custom genome browser
-Online genomic database
-Circo plots, pathway analysis
-Functional annotation of newly sequenced genomes
-Integrative analysis of RNA-Seq, ChIP-Seq, motif discovery, etc.
(see image in sidebar for representation of the experiment process)
Frustrated with genomic data? We can help!
You want straightforward answers, but instead you get a million data points which are hard to interpret. Current genomic data analysis solutions are often difficult to use, lack data mining capabilities, and require lengthy processing time.
The power of genomic data (when it's analyzed properly)
Rather than telling you that we offer RNA-Seq, ChIP-Seq, DNA-Seq, microarray and other analyses, we think it's more fun to demonstrate how real biological problems are answered with our approaches.
From Gene List to Functions
We make it easy to identify list of interested genes, and find out what common functions they have. Examples: Identify functions in genes involved in tumor metastasis (array or RNA-Seq); GO analysis for genes bound by a TCF7L2 transcription factor in liver cell line (ChIP-Seq).
Integral Analysis of Transcription Regulation
Our unique web-based database can easily combine results across experiments. With genome-wide motif analysis, expression profiling, and promoter occupancy, we can show that NR4A2 is a bona fide CREB target gene and view all results in a single web page.
Results with Meaningful Annotations
We make sure that all results are meaningful and easy to understand. For example, peaks from ChIP-Seq experiments will be mapped to genes, and enriched motifs, genomic features, and gene functions will be reported. Similarly, genetic variants from Exome sequencing will be annotated to help identify functional consequences.
Enhance your publication with a companion database
When you published a paper with omics data, the best way to publicize your results to the community is to build a searchable online database. The website will promote your publication, and get you more collaboration and funding opportunities! Below are some real publications where our team developed the companion websites. Contact us to learn how easy it is to build your own web database with BioInfoRx's unique technology.
How to Get Started
Simply contact us and tell us about your project, and our experts will work with you to figure out the best approach to obtain answers from your genomic data. We will provide a quote with timeline and cost, and you decide whether you want to proceed. With BioInfoRx, you will receive personal attention from our experts, who will work with you collaboratively to get biological meanings from your data quickly.
We process expression and ChIP-chip array data to help you answer biological questions. We also help you assess data quality and verify your experimental design, and deliver your data in an online database where you can perform additional data mining.
BxArrays™ is a web-based microarray data management and microarray analysis system for researchers who need to organize microarray data efficiently and get microarray data analyzed instantly. BxArrays™ supports all major microarray platforms, including Affymetrix, Agilent, NimbleGen, and more.
BxArrays™ organizes microarray data into projects for online microarray analysis with predefined or custom procedures. BxArrays™ integrates with Gene Expression Omnibus (GEO) and allows instantaneous re-analysis of published microarray data.
BxArrays Handles Your Microarray Data Management
It comes with integrated data management tools for contacts, projects, experiments, samples, and analysis results. It is an ideal system for both academic laboratories and biotechnology companies to manage samples and experimental details.
BxArrays Handles Your Microarray Data Analysis
Easy to use yet powerful analysis tools streamline this overwhelming process by taking millions of raw sequencing reads and transforming them into meaningful and easy-to-visualize data. All results can be visualized through our user friendly tools.
Designed with BxLIMS technology
BxArrays' excellent data management and sharing functions can manage microarray data including projects, samples, raw microarray data files, and analysis results. BxArrays™ comes with three highly automated and seamlessly integrated data analysis programs and a one-step data analysis tool. The microarray data can be from users’ own experiments (Custom Array Data), Gene Expression Omnibus (GEO) raw array data, or Gene Expression Omnibus (GEO) Curated DataSets.
BxArrays is a novel microarray data analysis and microarray data sharing system.
Its easy-to-use tools help both novice and experienced users perform initial analysis of their microarray data from the location of data storage. BxArrays™ tools are also valuable for re-analyzing published microarray data. BxArrays™ is a useful system for facilities with microarray services and laboratories involved with microarray data analysis.
BxArrays Key Features:
Control Microarray Data Files Visually
BxArrays contains built-in explorer-like online file management and group-based file sharing tools. While file owners have full control of their files (e.g. create new folders and files, rename or delete existing folders and files), group members can read, copy, and download others’ files, but are not allowed to make changes.
Organize and Find Your Data Easily
BxArrays contains a full-featured project and result search and browse tool. Users can browse project information page by page, update the viewing options, perform advanced searches, and download data in spreadsheet format.
Analyze All Published Microarray Data in a Few Clicks
Users can search for GEO DataSets, download CEL supplementary files, and create BxArrays™ projects to analyze previously published data. The sample information is automatically populated in the project based on the subset information stored in GEO GDS records.
Analyze All Sorts of Microarray Data FAST
Use Express Analysis to perform data analysis in minutes. Default analysis methods and parameters can be used directly due to our built-in logic. Experienced users have the option to select methods and enter specific analysis parameters.
BxArrays presents online directly. The resulting files, including executed scripts and execution logs, are classified, listed, hyper-linked, and compressed in one file for easy downloading.
We use a robust pipeline with flexible statistical models to identify differentially expressed genes (DEG) from raw RNA-Seq data. The list of DEG is only part of the results we delivery. We also help you assess data quality and verify your experimental design, and deliver your data in an online database where you can perform additional data mining:
We use best-practice method to map reads and make variant calls. We include robust quality control metrics for exome capture performance. The variants come with rich annotation regarding effects on genes and regulatory regions.
"I like their services, fast and reliable!"
"I would like to use the service of BioInfoRx for the next time. Their data analyses are fast and the pricing is economical. It is really excited to go with the team."
"Nice and quick analysis. Very satisfied with their service and will definitely work with them again."
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