Our mission is to provide best-in-class lead discovery solutions. Our proven teams of drug discovery professionals are passionate about unlocking the therapeutic potential of both genetically- and clinically-validated drug targets, and in developing new therapeutic modalities. We work in partnership with our clients to address the most difficult scientific and business challenges facing drug discovery, and to ultimately enable transformational health care outcomes.
Our integrated drug discovery services platform enables us to work across the entire pre-clinical research process. Our collaborations range from modular projects such as molecular engineering, biophysical screening, phenotypic screening or gene-to-structure as well as integrated drug-discovery programs where our partners utilize the full capability of the platform to develop drugs for challenging drug targets.
Our research team is diverse and deeply experienced in all aspects of drug discovery. As such, we start the process by hand-picking an internal Beryllium team for every single project – and ensure that the team is populated with the appropriate knowledge and expertise to ensure the success of the project. Depending on the scale, disciplines involved and duration of the project being planned, the team may be small or large, but always built appropriately for success. Our track record speaks for itself in collaborations with academia, virtual start-ups and large biopharma.
Efficiently sample target structure space
Obtain small molecule start points for your drug discovery program
Beryllium has a strong track record doing fragment screens by NMR.
Screening in-house collections
Screening external libraries
Pharma-Grade Facilities and Expertise:
Unleash the power of our NMR facility for superior structural insights
700 MHz Bruker Avance III:
500 MHz Varian Unity Inova
Unambiguously define your epitope-paratope interactions
Accelerate the development of your antibody therapeutic programs
We utilize our capacity to handle all projects- small and large. We deploy our extensive knowledge of target biology to overcome production challenges with even the most difficult targets. In addition to our experience, our project managers can custom design protocols for different types of protein targets, including specific gene families, membrane proteins, and difficult-to-fold proteins. We use a variety with innovative approaches, technologies and tools to enable proper expression, folding, purification, stability, and activity of challenging proteins and routinely achieve industry-leading levels of protein yield and purity needed for crystallization and other structural/functional biology applications.
Protein/Antibody Processing Capacity:
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