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B2S Life Sciences

Franklin, Indiana, US

B2S Life Sciences is a biotherapeutic enablement company advancing improved analytical methods and outcomes for companies involved in the development of biotherapeutic drugs and diagnostics. Our mission is to leverage extensive expertise in bioanalytical methods development and statistical analysis to provide superior custom reagent products and services that are tailored to our clients’ needs, and to manage these products and services for clients throughout the drug development process. As a result, our combination of expertise, products, and services thereby uniquely qualifies us to better the development process for biotherapeutic drugs and diagnostics.

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Clinical Biomarkers
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Reagent Life Cycle Management
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Reagent Development
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Biostatistical Analysis
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PK/PD Data Analysis
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Preclinical PK/PD Studies
in vivo Pharmacokinetics/Pharmacodynamics
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Assay Development
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Biomarker Analysis
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I. Bioanalytical strategies
II. Assay Development & Validation
III. Exploratory Data Analysis & Mining
IV. BioMarker Reference Standard Generation & Characterization

  • Biomarker discovery from high-dimensional array data, such as genomics, imaging, proteomics, etc.
  • Biomarker qualification, study design,... Show more »

I. Bioanalytical strategies
II. Assay Development & Validation
III. Exploratory Data Analysis & Mining
IV. BioMarker Reference Standard Generation & Characterization

  • Biomarker discovery from high-dimensional array data, such as genomics, imaging, proteomics, etc.
  • Biomarker qualification, study design, etc.
  • Development of optimal multivariate biomarker signatures for various objectives, such as patient stratification, predicting treatment response, disease diagnostic and progression
  • In-vitro screening assay evaluations
  • Clinical interpretation and association of immunogenicity data
  • Predictive modeling of clinical/invivo data
  • High-dimensional data analysis
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Bioanalytical Assay Development and Optimization
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We have been at the forefront of the development of scientifically based method validation. As co-authors on many of the currently cited “white papers,” we understand validation is not just “checking boxes” but an integral part of assessment and application of methods. Our ultimate goal is to make the bioanalytical sections of... Show more »

We have been at the forefront of the development of scientifically based method validation. As co-authors on many of the currently cited “white papers,” we understand validation is not just “checking boxes” but an integral part of assessment and application of methods. Our ultimate goal is to make the bioanalytical sections of submission a non-issue and to allow regulators to focus on safety and efficacy data.

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Ligand Binding Assays
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Unlike many bioanalytical consultants, our primary expertise is in the development, validation and application of ligand binding assays. With our combined experience (well over 100 years), there are few issues we have not seen before. We not only have experience with various technologies, we likely were participants in developing... Show more »

Unlike many bioanalytical consultants, our primary expertise is in the development, validation and application of ligand binding assays. With our combined experience (well over 100 years), there are few issues we have not seen before. We not only have experience with various technologies, we likely were participants in developing the techniques. As such, we know the strengths and weaknesses of each technology and can therefore help you pick the right technology based on your projects needs as well as where the assays will be performed.

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Statistical Analysis
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Drug Discovery
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With over three decades of experience in the successful implementation of discovery research, our team offers the following services in a broad range of drug discovery areas, including assays for drug screening, genomics, cell culture, gene transfer/gene therapy, physiology, and pharmacology.

Experimental Design &... Show more »

With over three decades of experience in the successful implementation of discovery research, our team offers the following services in a broad range of drug discovery areas, including assays for drug screening, genomics, cell culture, gene transfer/gene therapy, physiology, and pharmacology.

Experimental Design & Implementation of Studies—We will help you design and carry out your research in any of the above areas. We will first discuss your research ideas with you and will work with you to develop an optimal plan of implementation. This includes developing one or more of the following strategies prior to starting the actual research:

  • Drug Screening Assays, Activity Assays, Cell Culture
  • Statistical support for Design of Experiments (DOE)
  • Creating research protocols
  • Crafting proposals for submission to extramural funding agencies, including writing the text, creating figures, generating the budget, etc.
  • Producing documents (including text and figures) for presentation to institutional peer review committees
  • Establishing SOP’s
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Project and Process Management
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Experimental Design
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Clinical Research
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Clinical Laboratory Services
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Clinical Chemistry
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Antibody/Antigen Detection Based Testing
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Biology
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Cells and Tissues
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Cell Culture Media and Reagents
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Biochemistry & Molecular Biology
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Biomolecular Interaction Analysis
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Chemistry and Materials
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Synthetic Chemistry
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Peptide Synthesis
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Pharmacology & Toxicology
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In vitro ADME Studies
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Bioanalysis
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Biomarkers
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ADME/DMPK Studies
Drug Metabolism and Pharmacokinetics
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Drug Discovery & Development
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Computational Modeling
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Biostatistics & Bioinformatics
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Bioanalytical Assays
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Bioanalytical Assays Services

Bioanalytical Assays Services

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