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AvantiCell Science

1 Order Completed
Ayr, GB

About AvantiCell Science

Founded: 2006 Type: Privately Held Size: 11-50 employees

AvantiCell was founded on the principle that cell-based technologies offer valuable preclinical alternatives to animal testing. As a global provider of primary cell products and cell-based services, we offer the prospect of faster, more efficient progress towards better drugs and personalised medicine research.

As experts in primary cell culture, AvantiCell can successfully and ethically procure human tissue and isolate primary cells, with the aim to provide these as valuable tools for use in preclinical research.

By incorporating primary cells into novel, tailor-made 3D models, AvantiCell create physiologically-relevant and predictive platforms for preclinical analysis. The 3D printing of our primary cell models, together with their optimised extracellular matrix, provides a superior in vitro model for medium-throughput assay screening and access to more physiologically-relevant preclinical data.

We have dedicated experts immediately available to guide and shape your study - contact us anytime to begin detailed discussions on your research project.

Diversity Certificates

Small business

Our Services (12)


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3D Cell Culture Models

Price on request

- Customised options incorporating 3D cell models e.g. 3D human primary cancer models

- Barrier model incorporating human upper or lower respiratory airway primary cells 

Oncology Fibrotic Disease Respiratory Hepatology Colorectal cancer Breast cancer Human Non-human Cell culture Primary Cells Show 10 more tags Show less

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Cryopreservation

Price on request

- Application of AvantiCell's proprietary in situ cryopreservation technology CryotixTM to your cells

- User-friendly 2D/3D cryopreservation technology is successfully applicable to human primary cells, iPSC-derived cells with differentiated function and cell lines

Human Non-human Cell culture Primary Cells

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Human Primary Cell Isolation

Price on request

- Client-commissioned production of human primary cell types from client-specified donor criteria

- Production of working cell banks, including ultra-low freezer storage, until a time of your convenience

Human Cell culture Primary Cells

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Cell-Based Assays

Price on request

- Panel of standard 2D assays including viability, proliferation, cytotoxicity and apoptosis measurements

- Analysis of cell-type specific activities at protein or gene expression level

- Range of analytical readouts for example flourescence, luminescence, immunofluroescent staining, ELISA and qPCR

- Analytical targets customised according to client requirements 

Human Cell culture Primary Cells

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Custom Cell Model Development

Price on request

Do you require a specific and validated model for testing of your candidates? With years of experience in building cell-based models, AvantiCell's experts can develop the analytical model to suit your needs

Human Non-human Cell culture Primary Cells

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In vitro Biosafety Testing

Price on request

- Applicable in preclinical testing of candidate therapeutics

- Measured as cytotoxic damage to primary human cells relevant to tissues impacted by test materials or by damage to tissue repair mechanisms

Human Cell culture Primary Cells

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In vitro Wound Healing Assay

Price on request

- Evaluates candidate therapeutic promotion of wound healing activity by measuring cell migration into cleared cell-free “wound” area in vitro 

Human Cell culture Primary Cells

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In vitro Insulin Secretion Assay

Price on request

- Evaluates candidate therapeutic potential as enhancer of glucose-sensitive insulin secretion for Type I Diabetes treatment

- Measures pancreatic β-cell sensitivity in vitro to glucose-stimulated insulin secretion

- Analytical platform based upon human pancreatic islets exhibiting mobilisation of intracellular insulin stores in response to glucose challenge

- Test sample effect compared with known insulin secretory stimulants

Diabetes Human Metabolism and Endocrinology Cell culture Primary Cells

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Glucose Uptake Assays

Price on request

- Evaluates candidate therapeutic potential in terms of insulin sensitisation of peripheral tissues for Type II diabetes treatment

- Measures glucose uptake as intracellular accumulation of fluorescent non-metabolised glucose analogue

- Range of insulin-sensitive peripheral cell types available, including human primary adipocytes (from pre-adipocyte precursors) and myocytes (from myoblast precursors)

Diabetes Human Metabolism and Endocrinology Cell culture Primary Cells

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Anti-Inflammatory Drug Screening in Human Cells

Price on request

- Screening for inflammatory impact or anti-inflammatory potential measured as production of reactive oxygen species and/or induction of pro-inflammatory cytokines  

- Analysis options include medium-throughput whole human blood cell-based screening

- Single cytokine or multiplexed cytokine analyses available 

Inflammation Human Cell culture Primary Cells

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Drug Absorption Studies

Price on request

- Evaluates uptake of drugs, natural products or other materials across lung mucosal barrier

- Uptake measured as transport of fluorescently-tagged or biotinylated material across cell monolayers formed on permeable membranes 

Respiratory Gastroenterology Human Cell culture Primary Cells

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Antifibrotic Activity Assays

Price on request

- Evaluates test materials for potential to cause tissue damage by induction of fibrosis

- Analysis based upon fibroblast / myofibroblast conversion by cell population analysis or direct measurement of extracellular matrix deposition by collagen lattice assay

- Range of fibroblast cell types available representative of human organs with fibrotic susceptibility (kidney, lung and skin)

Fibrotic Disease Cell culture Human Primary Cells

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Sisely Parks

Sales Manager

FileType/PDF Created with Sketch. AvantiCell Product Catalogue Aug 2019.pdf

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FileType/PDF Created with Sketch. AvantiCell Science Contract Services Overview .pdf

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FileType/PDF Created with Sketch. Human Immune Cells Technology Overview.pdf

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