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AUM BioTech, LLC

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Philadelphia, Pennsylvania, US

About AUM BioTech, LLC

AUM BioTech is a biotechnology company that offers solutions and products for genetic research using next generation RNA silencing technology in diverse life science verticals including biomedical research, medicine, and agriculture. AUM's next generation FANA Antisense Oligonucleotide (FANA ASO) technology... Show more »

AUM BioTech is a biotechnology company that offers solutions and products for genetic research using next generation RNA silencing technology in diverse life science verticals including biomedical research, medicine, and agriculture. AUM's next generation FANA Antisense Oligonucleotide (FANA ASO) technology is globally being used by biomedical scientists and researchers working on basic, transitional and preclinical research. FANA ASO technology can be used to silence or regulate RNA modalities such as – mRNA, microRNA and long non-coding RNA. AUM's next generation FANA technology provides alternatives to CRISPR, siRNA and shRNA approaches. FANA oligos are self-deliverable and do not need any transfection reagents or delivery agents and can work both in in vitro and in vivo models. AUM's FANA ASO technology also provides next generation solutions for genetic research in agriculture and entomology. AUM BioTech’s 300,000-plus customized and cutting-edge RNA silencing products can be used to target thousands of genetic targets.

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Our Services (11)


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FANA Antisense Oligonucleotides

Price on request

Silence or regulate mRNA, microRNA or long non-coding RNA. FANA technology provides superior alternatives to CRISPR, siRNA and shRNA approaches.

Key Attributes: FANA Antisense Oligonucleotides (FANA – ASOs)

  • Self-deliverable - do not need any formulations, conjugates, transfection or delivery agents.
  • Ideal for hard... Show more »

Silence or regulate mRNA, microRNA or long non-coding RNA. FANA technology provides superior alternatives to CRISPR, siRNA and shRNA approaches.

Key Attributes: FANA Antisense Oligonucleotides (FANA – ASOs)

  • Self-deliverable - do not need any formulations, conjugates, transfection or delivery agents.
  • Ideal for hard to transfect cells like primary cells including immunological cells (like PBMCs, T cells, B cells, macrophages), neuronal cells, endothelial cells etc.
  • FANAs can be self-delivered into very sensitive primary cells from diseased donors and silence the desired RNA. Such study models can more accurately mimic the biology of the disease.
  • Ideal for animal studies and can be used via multiple modes of injections including intravenous (IV), intraperitoneal (IP), intradermal (ID), intratumoral (IT), intranasal (IN), intratracheal, hydrodynamic tail injection, inhalation, or local organ delivery.
  • Ideal for bacterial, viral and fungal research.
  • Ideal for agriculture and entomology research.
  • Non-toxic and resistant to degradation by serum and cellular nucleases.
  • Provide sustained silencing and does not alter the biology of the cells.
  • Ideal for target discovery.
  • Ideal for high throughput gene screening.
  • Single step knockdown will help save time, resources and money for researchers.

FANAs have high intracellular stability as well as high binding affinity to the target RNA forming very stable heteroduplex structures. Unlike conventional technologies, FANAs have high fidelity for the RNA target and highly reduced off target effects (no RISC associated off target effects). These attributes represent a more potent, efficient, and cost effective solution in the RNA silencing and regulation space.

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siRNA-Mediated Gene Knockdown

Price on request

FANA Antisense Oligonucleotide (FANA – ASO) technology provides is a superior alternative to siRNA-mediated gene knockdown.

FANA Antisense Oligonucleotide (FANA – ASO) technology provides is a superior alternative to siRNA-mediated gene knockdown.

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shRNA-Mediated Gene Knockdown

Price on request

FANA Antisense Oligonucleotide (FANA – ASO) technology provides an alternative to shRNA-mediated gene knockdown.

FANA Antisense Oligonucleotide (FANA – ASO) technology provides an alternative to shRNA-mediated gene knockdown.

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Morpholino-Mediated Gene Knockdown

Price on request

FANA Antisense Oligonucleotide (FANA – ASO) technology provides an alternative to conventional oligo approaches.

FANA Antisense Oligonucleotide (FANA – ASO) technology provides an alternative to conventional oligo approaches.

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CRISPR sgRNA Libraries

Price on request

FANA Antisense Oligonucleotide (FANA – ASO) technology provides an alternative to CRISPR sgRNA Libraries.

FANA Antisense Oligonucleotide (FANA – ASO) technology provides an alternative to CRISPR sgRNA Libraries.

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Genome Editing

Price on request

FANA Antisense Oligonucleotide (FANA – ASO) technology provides alternatives to genome editing approaches.

FANA Antisense Oligonucleotide (FANA – ASO) technology provides alternatives to genome editing approaches.

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CRISPR/Cas9 Genome Editing

Price on request

FANA Antisense Oligonucleotide (FANA – ASO) technology provides an alternative to CRISPR/Cas9 Genome Editing.

FANA Antisense Oligonucleotide (FANA – ASO) technology provides an alternative to CRISPR/Cas9 Genome Editing.

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Genetic Engineering

Price on request

Genetic Engineering Services

Genetic Engineering Services

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Custom Gene Synthesis

Price on request
Request a quote for more information about this service.

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Oligonucleotide Probes

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DNA Synthesis and Probe Development

Price on request

DNA Synthesis and Probe Development Services

DNA Synthesis and Probe Development Services

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Veenu Aishwarya

Chief Executive Officer
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FANA vs. shRNA.jpg

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FANA vs. siRNA.jpg

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FANA:siRNA Compare.jpg

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in vitro protocol.pdf

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in vivo protocol.pdf

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lncRNA knockdown.pdf

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miRNA inhibition.pdf

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miRNA mimic.pdf

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Mode of Action.jpg

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mRNA knockdown.pdf

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