Archer addresses the bottlenecks associated with using next-generation sequencing in translational research by offering a robust platform for targeted sequencing applications.
By combining proprietary Anchored Multiplexed PCR (AMP) chemistry and easy-to-use, lyophilized reagents, ArcherDX technology generates highly enriched sequencing libraries to detect gene fusions, SNPs, indels and CNVs. Complemented by the Archer suite of bioinformatics software and readily accessible reports, ArcherDX technology dramatically enhances complex mutation identification and discovery.
ArcherDX offers both catalog and custom panels for profiling mutations in RNA,DNA, and ctDNA as well as testing services and companion diagnostic development support.
ArcherDX, Inc. is headquartered in Boulder, Colorado.
Archer Anchored Multiplex PCR (AMP™) Chemistry
Developed by molecular pathologists, AMP is a rapid and scalable method to generate target-enriched libraries for next generation sequencing (NGS). AMP technology can be used for applications in targeted RNA sequencing, genomic DNA sequencing and genotyping applications, easily generating a sequencing library in a matter of hours. Designed for low nucleic acid input, this process delivers robust performance across a variety of sample types.
AMP is a robust platform to create target-enriched NGS libraries that excel over traditional PCR-based preparation methods. Unidirectional gene-specific primers (GSPs) enrich for both known and unknown mutations. Adapters that contain both molecular barcodes and sample indexes permit quantitative multiplex data analysis, read deduplication and accurate mutation calling.
Clinical Molecular Diagnostics Services
Next Generation Sequencing (NGS) Services
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