ArcherDX

Archer Anchored Multiplex PCR (AMP™) Chemistry

Developed by molecular pathologists, AMP is a rapid and scalable method to generate target-enriched libraries for next generation sequencing (NGS). AMP technology can be used for applications in targeted RNA sequencing, genomic DNA sequencing and genotyping applications, easily generating a sequencing library in a matter of hours. Designed for low nucleic acid input, this process delivers robust performance across a variety of sample types.

AMP is a robust platform to create target-enriched NGS libraries that excel over traditional PCR-based preparation methods. Unidirectional gene-specific primers (GSPs) enrich for both known and unknown mutations. Adapters that contain both molecular barcodes and sample indexes permit quantitative multiplex data analysis, read deduplication and accurate mutation calling.