Aracari’s patented Vascularized Micro-Organ (VMO) and Vascularized Micro-Tumor (VMT) devices faithfully recreate complex 3D cellular structures embedded in a natural matrix, where oxygen and nutrients are transported through naturally-forming blood vessels. They are a much more effective platform for investigating the complexity of human organs and tumors in a highly reproducible and scalable way. Uniquely suited for preclinical screening of new drugs for: tissue uptake, including Blood-Brain Barrier permeability; efficacy; and, vascular toxicity. In addition, delivery of leukocytes through the vessels allows for screening of immuno-oncology reagents. Aracari technology has successfully recreated several micro organs, including heart, liver, pancreas and brain that we believe will speed the drug discovery process, while reducing costs, and herald a new era of precision medicine.
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