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Analiza

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ic 21 Orders Completed
Cleveland, Ohio, US

About Analiza

Type: Privately Held Size: 11-50 employees

Analiza, Inc. is a privately held corporation dedicated to discovering, developing, and commercializing new technologies for the life sciences. Analiza provides integrated solutions to key applications in the pharmaceutical, biotechnology and diagnostics industries.

We provide access to our technologies... Show more »

Analiza, Inc. is a privately held corporation dedicated to discovering, developing, and commercializing new technologies for the life sciences. Analiza provides integrated solutions to key applications in the pharmaceutical, biotechnology and diagnostics industries.

We provide access to our technologies through contract research services:

  • High-quality, gold-standard assays for accurate determination of Physchem parameters, including LogD/LogP, solubility (aqueous and other), pKa and other information critical for understanding the interaction between the body and a drug candidate. We also pioneered fast, accurate measurements of physicochemical parameters such as solubility to provide key interpretation data obtained from in vitro biological assays. Our data are measured using patented, innovative robotic platforms that enable high-throughput, low-cost, and highly accurate results that mean the same throughout the drug discovery and early development process.
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Our Services (12)


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Solubility and Dissolution Testing

Price on request

We use miniaturized, gold standard shake flask assays to measure kinetic solubility from DMSO stock solutions (minimum 15 µl of 10mM DMSO stock solution required per sample) or thermodynamic solubility from dry powder (minimum 2 mg dry powder required per sample). Pricing varies with detection method (choice of chemiluminescent nitrogen detection (CLND), HPLC-UV, or HPLC-MS).

We use miniaturized, gold standard shake flask assays to measure kinetic solubility from DMSO stock solutions (minimum 15 µl of 10mM DMSO stock solution required per sample) or thermodynamic solubility from dry powder (minimum 2 mg dry powder required per sample). Pricing varies with detection method (choice of chemiluminescent nitrogen detection (CLND), HPLC-UV, or HPLC-MS).

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Antek Nitrogen Detector Agilent 6500 QTOF MS Agilent 1100

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pKa Measurement

Price on request

Using a parrallel capillary electrophoresis method, we are able to provide you pKa values using aqueous and cosolvent buffers with a minimum sample size of only 30 µl of 10mM DMSO stock solution.

Using a parrallel capillary electrophoresis method, we are able to provide you pKa values using aqueous and cosolvent buffers with a minimum sample size of only 30 µl of 10mM DMSO stock solution.

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Advanced Analytical pKa Pro 96XT

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Parallel Artificial Membrane Permeability Assay (PAMPA)

Parallel Artificial Membrane Permeability Assay
Price on request

Using the Corning Gentest™ pre-coated PAMPA plate system, we are able to generate data with only 20 µl of 10mM DMSO stock solution. Pricing varies with detection method (choice of chemiluminescent nitrogen detection (CLND), HPLC-UV, or HPLC-MS).

Using the Corning Gentest™ pre-coated PAMPA plate system, we are able to generate data with only 20 µl of 10mM DMSO stock solution. Pricing varies with detection method (choice of chemiluminescent nitrogen detection (CLND), HPLC-UV, or HPLC-MS).

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LogP/LogD Determination

Price on request

We have scaled down the gold standard shake-flask method to deliver accurate data from just 30 µl of 10mM DMSO stock solution. LogP is determined after using measured pKa data.

We have scaled down the gold standard shake-flask method to deliver accurate data from just 30 µl of 10mM DMSO stock solution. LogP is determined after using measured pKa data.

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Chemical Stability Testing

Price on request

Our automated short-term chemical stability assay mimics the short gastrointestinal transit time and in vitro biology conditions, delivering stability-pH profiles in as little as 72 hours. Minimum of 25 µl of 10mM DMSO stock solution per sample is required.

Our automated short-term chemical stability assay mimics the short gastrointestinal transit time and in vitro biology conditions, delivering stability-pH profiles in as little as 72 hours. Minimum of 25 µl of 10mM DMSO stock solution per sample is required.

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Agilent 1100

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CYP Inhibition Assay

Price on request

Minimum sample requirement of 10 µl of 10mM stock solution.

Minimum sample requirement of 10 µl of 10mM stock solution.

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Agilent 6500 QTOF MS

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Microsomal Stability Assay

Price on request

Minimum sample requirement of 10 µl of 10mM stock solution.

Minimum sample requirement of 10 µl of 10mM stock solution.

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Agilent 6500 QTOF MS

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In vitro ADME/DMPK Studies

Price on request

Founded in 1996 in Cleveland, OH, Analiza, Inc. is a leading US based provider of high quality, affordable analytical services for physicochemical and ADME properties for early drug discovery markets. Adapting gold standard methods for compatibility with early drug discovery (throughput, sample requirements, turnaround time, and... Show more »

Founded in 1996 in Cleveland, OH, Analiza, Inc. is a leading US based provider of high quality, affordable analytical services for physicochemical and ADME properties for early drug discovery markets. Adapting gold standard methods for compatibility with early drug discovery (throughput, sample requirements, turnaround time, and cost), Analiza developed the first automated, miniaturized, shake flask system for LogD in 1999. In 2005 this platform became the foundation of Analiza’s current Contract Research Organization operational base. Since 2005 Analiza has provided over 150,000 solubility measurements, 45,000 LogD measurements and 2,500 pKa measurements. Analiza extends the in-house physchem and ADME profiling capabilities of small and large pharma and biotech alike. We do the grunt work when you can’t.

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X-Ray Diffraction (XRD)

Price on request

We can determine whether a compound is in its crystalline or amorphous form using XRD. Minimum 2 mg dry powder required per sample and can also be used for subsequent solubility analysis.

We can determine whether a compound is in its crystalline or amorphous form using XRD. Minimum 2 mg dry powder required per sample and can also be used for subsequent solubility analysis.

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Bruker D8 Powder X-Ray Diffractometer

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Physicochemical Testing

Price on request
Request a quote for more information about this service.

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Analytical Chemistry Services

Price on request
Request a quote for more information about this service.

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Drug Discovery & Development

Price on request

Drug Discovery & Development Services

Drug Discovery & Development Services

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Kate Favre

Senior Account Manager

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