Ampersand Biosciences LLC

Ampersand Biosciences specializes in the development, manufacturing & validation of high quality immunoassays.

Publications

• Jani D, Allinson J, Berisha F, Cowan KJ, Devanarayan V, Gleason C, Jeromin A, Keller S, Khan MU, Nowatzke B, Rhyne P, Stephen L. Recommendations for Use and Fit-for-Purpose Validation of Biomarker Multiplex Ligand Binding Assays in Drug Development. AAPS J. 2016 18(1):1-14
• Srivastava AK, Jaganathan S, Stephen L, Hollingshead MG, Layhee A, Damour E, Govindharajulu JP, Donohue J, Esposito D, Mapes JP, Kinders RJ, Takebe N, Tomaszewski JE, Kummar S, Doroshow JH, Parchment RE. Effect of a Smac Mimetic (TL32711, Birinapant) on the Apoptotic Program and Apoptosis Biomarkers Examined with Validated Multiplex Immunoassays Fit for Clinical Use. Clin Cancer Res. 2016 22(4):1000-10.
• Khan MU, Bowsher RR, Cameron M, Devanarayan V, Keller S, King L, Lee J, Morimoto A, Rhyne P, Stephen L, Wu Y, Wyant T, Lachno DR. Recommendations for adaptation and validation of commercial kits for biomarker quantification in drug development. Bioanalysis. 2015;7(2):229-42.
• Kobayashi DT, Shi J, Stephen L, Ballard KL, Dewey R, Mapes J, Chung B, McCarthy K, Swoboda KJ, Crawford TO, Li R, Plasterer T, Joyce C; Biomarkers for Spinal Muscular Atrophy Study Group, Chung WK, Kaufmann P, Darras BT, Finkel RS, Sproule DM, Martens WB, McDermott MP, De Vivo DC; Walker MG, Chen KS. SMA-MAP: a plasma protein panel for spinal muscular atrophy. PLoS One. 2013;8(4):e60113.
• Casrouge A, Bisiaux A, Stephen L, Schmolz M, Mapes J, Pfister C, Pol S, Mallet V, Albert ML. Discrimination of agonist and antagonist forms of CXCL10 in biological samples. Clin Exp Immunol 2012 167:137-48.
• Yip P, Chen TH, Seshaiah P, Stephen LL, Michael-Ballard KL, Mapes JP, Mansfield BC, Bertenshaw GP. Comprehensive serum profiling for the discovery of epithelial ovarian cancer biomarkers. PLoS One. 2011;6(12):e29533.
  • Seshaiah, P., G.P. Bertenshaw, T.-H. Chen, K.J. Bergstrom, J. Zhao, J.M. Mapes, L.L. Stephen, S. Amonkar, M.E. McCollum, B.E. Miller, L.D. Roman, B.Y. Karlan, E. Chalas, P.A. DiSilvestro, J.F. Barter, J. Orr, J. W., G.E. Bigsby IV, R.W. Holloway, R.D. Alvarez, P.F. Yip, and B.C. Mansfield, Validation of a Multivariate Serum Profile for Epithelial Ovarian Cancer Using a Prospective Multi-Site Collection. Nature Precedings, 2010.
• Wittemann S., Eisinger, DP, Stephen, LL, and TO. Joos. (2007) Multiplexed immunoassays for protein profiling in human body fluids. In: V. Thongboonkerd, Ed. Proteomics of Human Body Fluids: Principles, methods and applications. New Jersey. The Human Press Inc.