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Allotropic Tech

Halethorpe, Maryland, US

Allotropic Tech is a custom protein/enzyme production company. We are differentiated from traditional baculovirus expression; we utilize live whole insect larvae as our biomass instead of SF9 cells. Our system is a unique and powerful protein expression platform that combines well-established recombinant baculovirus technology with oral (via insect diet) infection of synchronous Trichoplusia ni larvae. The system is efficient and reproducible, which results in high level target protein expression. The core competitive advantages of Allotropic Tech's larval expression systems are speed, flexibility, scalability and low cost.

Additional key advantages of our proprietary larval system include:

  1. The tissue heterogeneity of larvae (compared to the homogeneity of cultured cells) can be a significant advantage for difficult to produce proteins: larvae can out-produce cultured cells by significant margins for... Show more »

Allotropic Tech is a custom protein/enzyme production company. We are differentiated from traditional baculovirus expression; we utilize live whole insect larvae as our biomass instead of SF9 cells. Our system is a unique and powerful protein expression platform that combines well-established recombinant baculovirus technology with oral (via insect diet) infection of synchronous Trichoplusia ni larvae. The system is efficient and reproducible, which results in high level target protein expression. The core competitive advantages of Allotropic Tech's larval expression systems are speed, flexibility, scalability and low cost.

Additional key advantages of our proprietary larval system include:

  1. The tissue heterogeneity of larvae (compared to the homogeneity of cultured cells) can be a significant advantage for difficult to produce proteins: larvae can out-produce cultured cells by significant margins for many proteins.
  2. High natural lipid content of larvae enables production and purification of many membrane-embedded and membrane-associated recombinant proteins which are not readily produced using other expression systems.
  3. Improved post-translational modifications and protein maturation including SS cleavage, N-glycosylation-S-S bonds formation.
  4. Ability to form dimers and tetramers.

We are a full service supplier; our offerings includes analyzing and modifying (if necessary) sequences to achieve customer’s expression goals, optimize design of baculovirus for insect expression, produce baculovirus, test expression, produce infected biomass and supply highly purify protein.

We welcome projects ranging from small exploratory projects to large scale production.

Allotropic Tech is located in Baltimore Maryland in close proximity to many of the largest government research laboratories and significant research universities. We have supplies proteins to many of these organizations.

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Protein Expression
Price on request

Insect based recombinant protein production – Pricing on request.
We are differentiated from traditional baculovirus expression; we utilize live whole insect larvae as our biomass instead of SF9 cells. This unique expression system provides many benefits.

Insect based recombinant protein production – Pricing on request.
We are differentiated from traditional baculovirus expression; we utilize live whole insect larvae as our biomass instead of SF9 cells. This unique expression system provides many benefits.

« Show less
Protein Purification and Quantification
Price on request

Insect based recombinant protein production – Pricing on request.
We are differentiated from traditional baculovirus expression; we utilize live whole insect larvae as our biomass instead of SF9 cells. This unique expression system provides many benefits.

Insect based recombinant protein production – Pricing on request.
We are differentiated from traditional baculovirus expression; we utilize live whole insect larvae as our biomass instead of SF9 cells. This unique expression system provides many benefits.

« Show less
Protein Purification
Price on request

Insect based recombinant protein production – Pricing on request.
We are differentiated from traditional baculovirus expression; we utilize live whole insect larvae as our biomass instead of SF9 cells. This unique expression system provides many benefits.

Insect based recombinant protein production – Pricing on request.
We are differentiated from traditional baculovirus expression; we utilize live whole insect larvae as our biomass instead of SF9 cells. This unique expression system provides many benefits.

« Show less
Biology
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Biochemistry & Molecular Biology
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Protein Services
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